Patents by Inventor James V. Bacus
James V. Bacus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7792338Abstract: A method and apparatus for creating a magnified composite image of a microscope specimen comprises making error corrections for imprecise movements of the specimen relative to an objective lens when capturing data for first and second images. A correction offset is computed based on a comparison of data for overlapped portions of the first and second images and then the specimen is moved through a distance modified by the correction offset for capture of a subsequent tiled image. Image center portions are retained as the data structure tile. The area about the center portion is used to align images and to compensate for stage inaccuracies and to provide a feedback signal for a drive system. Differences in X, Y coordinates for macro and micro view images may be used as navigation offsets to view a selected point for the micro image marked on the macro image.Type: GrantFiled: August 11, 2005Date of Patent: September 7, 2010Assignee: Olympus America Inc.Inventors: James V. Bacus, James W. Bacus
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Publication number: 20100074489Abstract: A virtual microscope slide includes images of a specimen for a given level of optical magnification which are associated and stored in a data structure. The forming of the data structure having the multiple Z-plane images preferably includes automatically focusing at a principal reference focal plane and capturing and digitizing an optically magnified reference Z-image and then shifting the specimen relative to the lens system by a predetermined increment to capture and digitize another Z-plane image. Preferably, a multiple sequence of Z-plane images above and below the reference image and captured and digitized. For ease of retrieval and use, each reference image has its associated Z-plane images are formed in a stack that is sent over the Internet, or Intranet to a local computer storage for quick retrieval when a viewer wants to mimic a focusing up or down to better view a detail in an image.Type: ApplicationFiled: August 28, 2009Publication date: March 25, 2010Applicant: Olympus America Inc.Inventors: James V. Bacus, James W. Bacus
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Patent number: 7596249Abstract: A virtual microscope slide includes images of a specimen for a given level of optical magnification which are associated and stored in a data structure. The forming of the data structure having the multiple Z-plane images preferably includes automatically focusing at a principal reference focal plane and capturing and digitizing an optically magnified reference Z-image and then shifting the specimen relative to the lens system by a predetermined increment to capture and digitize another Z-plane image. Preferably, a multiple sequence of Z-plane images above and below the reference image and captured and digitized. For ease of retrieval and use, each reference image has its associated Z-plane images are formed in a stack that is sent over the Internet, or Intranet to a local computer storage for quick retrieval when a viewer wants to mimic a focusing up or down to better view a detail in an image.Type: GrantFiled: February 24, 2003Date of Patent: September 29, 2009Assignee: Olympus America Inc.Inventors: James V. Bacus, James W. Bacus
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Publication number: 20090210809Abstract: A method of and apparatus for viewing microscopic images include transmitting tiled microscopic images from a server to a client. The client assembles the tiled images into a seamless virtual slide or specimen image and provides tools for manipulating image magnification and viewpoint. The method and apparatus also provides a virtual multi-headed microscope function which allows scattered viewers to simultaneously view and interact with a coherent magnified microscopic image.Type: ApplicationFiled: April 29, 2009Publication date: August 20, 2009Inventors: James W. Bacus, James V. Bacus
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Patent number: 7542596Abstract: A method of and apparatus for viewing microscopic images include transmitting tiled microscopic images from a server to a client. The client assembles the tiled images into a seamless virtual slide or specimen image and provides tools for manipulating image magnification and viewpoint. The method and apparatus also provides a virtual multi-headed microscope function which allows scattered viewers to simultaneously view and interact with a coherent magnified microscopic image.Type: GrantFiled: March 22, 2006Date of Patent: June 2, 2009Assignee: Olympus America Inc.Inventors: James W. Bacus, James V. Bacus
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Patent number: 7149332Abstract: A method of and apparatus for viewing microscopic images include transmitting tiled microscopic images from a server to a client. The client assembles the tiled images into a seamless virtual slide or specimen image and provides tools for manipulating image magnification and viewpoint. The method and apparatus also provides a virtual multi-headed microscope function which allows scattered viewers to simultaneously view and interact with a coherent magnified microscopic image.Type: GrantFiled: January 5, 2004Date of Patent: December 12, 2006Assignee: Bacus Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus
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Patent number: 7146372Abstract: A method and apparatus are disclosed for making and using a virtual microscope slide data structure having data for an overall image of the specimen or a substantial portion thereof along with data for higher magnification images of selected areas within the overall image and along with data useable for correlating, linking and/or coherently assembling low magnification, overall image segments with the higher image segments. This latter data may comprise a control program for manipulating images to allow zooming different, higher magnification images into view, scrolling adjacent high magnification images into view or marking the location of a displayed higher magnification view on the overall image to assist in navigation by a viewer to locate and quickly display suspicious areas within the specimen. The data structure may be sent over the Internet.Type: GrantFiled: June 16, 2004Date of Patent: December 5, 2006Assignee: Olympus America Inc.Inventors: James W. Bacus, James V. Bacus
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Patent number: 7110586Abstract: An apparatus and method acquires and stores multiple resolution images from a specimen on a support and provides to the user a low magnification, reconstructed macro image of the entire specimen, or a large portion thereof, to aid the person in selecting points of interest to be viewed or analyzed at higher magnifications and resolution. The reconstructed image is formed of a large number of tiled, stored images which are coordinated and assembled to form the macro image of the specimen which is displayed on a monitor. Preferably, the stored, reconstructed image is reduced further in size by a software system before it is displayed to the user. The display may be on a local monitor over a local area network or sent over the Internet to the user who is typically a pathologist. The user selects by a marker such as a cursor the defined area of interest or region and then views higher magnification images or has them analyzed.Type: GrantFiled: January 5, 2004Date of Patent: September 19, 2006Assignee: Bacus Laboratories, Inc.Inventors: James V. Bacus, James W. Bacus
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Patent number: 7031507Abstract: A method and apparatus for processing an image of a tissue sample microarray include placing a plurality of tissue samples in an array on a microscope slide. The tissue samples are then simultaneously and uniformly treated, as by staining. Images of the tissue making up the microarray are captured and stored together with identifying information related thereto. The images may be displayed from the digital storage medium using a programmed processor which can select various magnifications for display. The images also can be accessed by network and remotely.Type: GrantFiled: October 15, 2002Date of Patent: April 18, 2006Assignee: Bacus Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus
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Publication number: 20040236773Abstract: A method and apparatus are disclosed for constructing a virtual microscope slide comprised of digitally scanned images from a microscope specimen. The digitally scanned images are arranged in a tiled format convenient for viewing without a microscope, and for transferring the tiled images for viewing by another at a remote location. Several original microscope views at a low magnification are digitized and stored as digitized images coherently seamed together to provide an overall virtual, macro image of the specimen at a lower resolution. Several original microscope views at higher magnifications are digitized and stored as digitized images coherently seamed together to provide virtual micro images at higher resolution. A data structure is formed with these virtual macro and micro digitized images along with their mapping coordinates. Preferably, a generic viewing program is also provided in the data structure that allows remote users to manipulate and interpret the tiled images on the user's monitor.Type: ApplicationFiled: June 16, 2004Publication date: November 25, 2004Applicant: Bacus Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus
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Patent number: 6775402Abstract: A method and apparatus are disclosed for constructing a virtual microscope slide comprised of digitally scanned images from a microscope specimen. The digitally scanned images are arranged in a tiled format convenient for viewing without a microscope, and for transferring the tiled images for viewing by another at a remote location. Several original microscope views at a low magnification are digitized and stored as digitized images coherently seamed together to provide an overall virtual, macro image of the specimen at a lower resolution. Several original microscope views at higher magnifications are digitized and stored as digitized images coherently seamed together to provide virtual micro images at higher resolution. A data structure is formed with these virtual macro and micro digitized images along with their mapping coordinates. Preferably, a generic viewing program is also provided in the data structure that allows remote users to manipulate and interpret the tiled images on the user's monitor.Type: GrantFiled: February 12, 2003Date of Patent: August 10, 2004Assignee: Bacus Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus
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Publication number: 20040141637Abstract: A method of and apparatus for viewing microscopic images include transmitting tiled microscopic images from a server to a client. The client assembles the tiled images into a seamless virtual slide or specimen image and provides tools for manipulating image magnification and viewpoint. The method and apparatus also provides a virtual multi-headed microscope function which allows scattered viewers to simultaneously view and interact with a coherent magnified microscopic image.Type: ApplicationFiled: January 5, 2004Publication date: July 22, 2004Applicant: Bacus Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus
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Publication number: 20040136582Abstract: An apparatus and method acquires and stores multiple resolution images from a specimen on a support and provides to the user a low magnification, reconstructed macro image of the entire specimen, or a large portion thereof, to aid the person in selecting points of interest to be viewed or analyzed at higher magnifications and resolution. The reconstructed image is formed of a large number of tiled, stored images which are coordinated and assembled to form the macro image of the specimen which is displayed on a monitor. Preferably, the stored, reconstructed image is reduced further in size by a software system before it is displayed to the user. The display may be on a local monitor over a local area network or sent over the Internet to the user who is typically a pathologist. The user selects by a marker such as a cursor the defined area of interest or region and then views higher magnification images or has them analyzed.Type: ApplicationFiled: January 5, 2004Publication date: July 15, 2004Applicant: Bacus Laboratories, Inc.Inventors: James V. Bacus, James W. Bacus
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Publication number: 20040004614Abstract: A virtual microscope slide includes images of a specimen for a given level of optical magnification which are associated and stored in a data structure. The forming of the data structure having the multiple Z-plane images preferably includes automatically focusing at a principal reference focal plane and capturing and digitizing an optically magnified reference Z-image and then shifting the specimen relative to the lens system by a predetermined increment to capture and digitize another Z-plane image. Preferably, a multiple sequence of Z-plane images above and below the reference image and captured and digitized. For ease of retrieval and use, each reference image has its associated Z-plane images are formed in a stack that is sent over the Internet, or Intranet to a local computer storage for quick retrieval when a viewer wants to mimic a focusing up or down to better view a detail in an image.Type: ApplicationFiled: February 24, 2003Publication date: January 8, 2004Applicant: Bacus Laboratories, Inc.Inventors: James V. Bacus, James W. Bacus
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Patent number: 6674881Abstract: A method of and apparatus for viewing microscopic images include transmitting tiled microscopic images from a server to a client. The client assembles the tiled images into a seamless virtual slide or specimen image and provides tools for manipulating image magnification and viewpoint. The method and apparatus also provides a virtual multi-headed microscope function which allows scattered viewers to simultaneously view and interact with a coherent magnified microscopic image.Type: GrantFiled: December 14, 2001Date of Patent: January 6, 2004Assignee: Bacus Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus
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Patent number: 6674884Abstract: An apparatus and method acquires and stores multiple resolution images from a specimen on a support and provides to the user a low magnification, reconstructed macro image of the entire specimen, or a large portion thereof, to aid the person in selecting points of interest to be viewed or analyzed at higher magnifications and resolution. The reconstructed image is formed of a large number of tiled, stored images which are coordinated and assembled to form the macro image of the specimen which is displayed on a monitor. Preferably, the stored, reconstructed image is reduced further in size by a software system before it is displayed to the user. The display may be on a local monitor over a local area network or sent over the Internet to the user who is typically a pathologist. The user selects by a marker such as a cursor the defined area of interest or region and then views higher magnification images or has them analyzed.Type: GrantFiled: November 13, 2001Date of Patent: January 6, 2004Assignee: Bacus Laboratories, Inc.Inventors: James V. Bacus, James W. Bacus
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Publication number: 20030123717Abstract: A method and apparatus are disclosed for constructing a virtual microscope slide comprised of digitally scanned images from a microscope specimen. The digitally scanned images are arranged in a tiled format convenient for viewing without a microscope, and for transferring the tiled images for viewing by another at a remote location. Several original microscope views at a low magnification are digitized and stored as digitized images coherently seamed together to provide an overall virtual, macro image of the specimen at a lower resolution. Several original microscope views at higher magnifications are digitized and stored as digitized images coherently seamed together to provide virtual micro images at higher resolution. A data structure is formed with these virtual macro and micro digitized images along with their mapping coordinates. Preferably, a generic viewing program is also provided in the data structure that allows remote users to manipulate and interpret the tiled images on the user's monitor.Type: ApplicationFiled: February 12, 2003Publication date: July 3, 2003Applicant: Bacus Research Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus
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Publication number: 20030039384Abstract: A method and apparatus for processing an image of a tissue sample microarray include placing a plurality of tissue samples in an array on a microscope slide. The tissue samples are then simultaneously and uniformly treated, as by staining. Images of the tissue making up the microarray are captured and stored together with identifying information related thereto. The images may be displayed from the digital storage medium using a programmed processor which can select various magnifications for display. The images also can be accessed by network and remotely.Type: ApplicationFiled: October 15, 2002Publication date: February 27, 2003Applicant: Bacus Research Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus
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Patent number: 6522774Abstract: A method and apparatus are disclosed for constructing a virtual microscope slide comprised of digitally scanned images from a microscope specimen. The digitally scanned images are arranged in a tiled format convenient for viewing without a microscope, and for transferring the tiled images for viewing by another at a remote location. Several original microscope views at a low magnification are digitized and stored as digitized images coherently seamed together to provide an overall virtual, macro image of the specimen at a lower resolution. Several original microscope views at higher magnifications are digitized and stored as digitized images coherently seamed together to provide virtual micro images at higher resolution. A data structure is formed with these virtual macro and micro digitized images along with their mapping coordinates. Preferably, a generic viewing program is also provided in the data structure that allows remote users to manipulate and interpret the tiled images on the user's monitor.Type: GrantFiled: May 19, 2000Date of Patent: February 18, 2003Assignee: Bacus Research Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus
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Patent number: 6466690Abstract: A method and apparatus for processing an image of a tissue sample microarray include placing a plurality of tissue samples in an array on a microscope slide. The tissue samples are then simultaneously and uniformly treated, as by staining. Images of the tissue making up the microarray are captured and stored together with identifying information related thereto. The images may be displayed from the digital storage medium using a programmed processor which can select various magnifications for display. The images also can be accessed by network and remotely.Type: GrantFiled: December 19, 2000Date of Patent: October 15, 2002Assignee: Bacus Research Laboratories, Inc.Inventors: James W. Bacus, James V. Bacus