Abstract: Mid-infrared spectroscopic analysis of tissue specimens can include training a learning model and using the trained learning model to classify tissue into at least two (or more than two) categories such as a tumor category, a non-tumor category, and a histology category. Resulting richer diagnostic indication can be provided and can optionally be mapped to a schema for RGB or other display. Efficient and accurate classification can employ an efficient linear SVM model representation. The model representation can include a ? spectrum including the fuller wavelength set, a central tendency indicator (?) of the training set, a spread indicator (?) of the training set, and a scaling factor. Various types of illuminators and response detectors can include one or more Quantum Cascade Lasers, broadband light source configured to permit spectral separation, a thermal or other imaging array, among others.

Abstract: Mid-infrared spectroscopic analysis of tissue specimens can include training a learning model and using the trained learning model to classify tissue into at least two (or more than two) categories such as a tumor category, a non-tumor category, and a histology category. Resulting richer diagnostic indication can be provided and can optionally be mapped to a schema for RGB or other display. Efficient and accurate classification can employ an efficient linear SVM model representation. The model representation can include a ? spectrum including the fuller wavelength set, a central tendency indicator (?) of the training set, a spread indicator (?) of the training set, and a scaling factor. Various types of illuminators and response detectors can include one or more Quantum Cascade Lasers, broadband light source configured to permit spectral separation, a thermal or other imaging array, among others.

Abstract: Signal processing techniques that can include an embedded software low-noise response pulse detection, which can help provide an enhanced signal-to-noise characteristic, such as can help permit highly specific fast IR spectroscopic tissue analysis. Using a difference between (1) response signal values during a first time period duration of a response pulse from a tissue sample illuminated by illumination pulse, and (2) response signal values for a similar first time period duration between response pulses, for a low duty cycle (e.g., less than 50%, 10% or even at about 5% duty cycle) illumination pulse, accumulation of noise in the response signal between electromagnetic illumination pulses can be limited. In particular, the described signal pre-processing techniques can help extract meaningful information for performing spectroscopic analysis and characterization of the tissue sample despite amplitude and temporal variations that can be encountered when using the system.

Abstract: A coated metallic mesh having a molecular layer thereon comprising: (1) a metallic mesh comprising at least one aperture; (2) a coating disposed on the metallic mesh that at least partially fills at least one aperture so as to form a partially-filled aperture; and (3) a molecular layer comprising at least one molecule having a hydrophilic region and a hydrophobic region, wherein the hydrophilic region at least partially extends into the partially-filled aperture. Also, provided are coated metallic meshes having bilayers and a method of providing a molecular layer to a coated mesh.

Abstract: A method for electrodepositing a uniformly thick coating on a metallic mesh is provided, the method comprises the steps of: (1) providing a metallic mesh having a plurality of apertures having at least one dimension greater than nanometer scale sizes; (2) subjecting the metal mesh to a relatively fast deposition of an electrodeposited material so as to substantially uniformly coat said mesh with electrodeposited material; and (3) subjecting the product of the relatively fast deposition step to a relatively slow deposition of an electrodeposited material so as to reduce at least one dimension greater than nanometer scale size to a size of nanometer scale. Also provided are metallic meshes so prepared and spectral filters.

Abstract: The invention relates to an improved synthesis of fullerene (C.sub.60) films, whereby improved purity and adhesion to a substrate are achieved. The invention is not limited to C.sub.60 molecules and other fullerenes and fullerene based materials, including for example, metallofullerenes, fluorinated fullerenes, and codeposition of fullerene and other solid lubricants. The invention also relates to the use of these fullerene materials in oils, greases, polymers and other materials, both organic and inorganic, for improving lubrication and wear life. The invention further relates to a process for the ion bombardment of fullerene materials, including but not limited to, C.sub.60 fullerene materials to improve their tribological properties.