Patents by Inventor James Vincent

James Vincent has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250154229
    Abstract: Provided herein is a method for reducing a lactate spike and increasing titer in a fed-batch process for producing a protein of interest, comprising reducing pyruvate (e.g., sodium pyruvate) concentration in one or more feeds to cells in a bioreactor in the fed-batch process.
    Type: Application
    Filed: January 31, 2023
    Publication date: May 15, 2025
    Inventors: James Vincent Price, Stefanie Berges-Vorsanger, Kevin Clark
  • Publication number: 20250114538
    Abstract: A method and system for detecting a limit of use of a medical device is disclosed. The method includes starting a timer of a medical device when said medical device is used for the first time, detecting the limit of use of the medical device and indicating the limit of use of the medical device. The limit of use is reached when at least one of a first criterion and a second criterion is met, wherein the first criterion is that the timer reaches or exceeds a time limit and wherein the second criterion is that at least one operation of a drive train of said medical device reaches or exceeds a limit.
    Type: Application
    Filed: May 22, 2024
    Publication date: April 10, 2025
    Inventors: Ilona Eggert, Michael Caspers, Richard James Vincent Avery, Shane Alistair Day
  • Publication number: 20250110139
    Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.
    Type: Application
    Filed: December 11, 2024
    Publication date: April 3, 2025
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
  • Publication number: 20250099685
    Abstract: A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.
    Type: Application
    Filed: December 9, 2024
    Publication date: March 27, 2025
    Inventors: Richard James Vincent Avery, Malcolm Stanley Boyd, Oliver Charles Gazeley, Gareth James Lewis, David Aubrey Plumptre, James Alexander Senior
  • Patent number: 12219985
    Abstract: Apparatus is disclosed for orientating a tobacco product containing a strip component. The apparatus comprises means for producing an image of the tobacco product, means for determining an apparent width of the strip component from the image, means for determining an amount of rotation of the tobacco product based on the apparent width, and means for rotating the tobacco product relative to the imaging means by the determined amount of rotation. This may allow the product to be rotated such that the strip component has a known orientation with respect to the imaging means.
    Type: Grant
    Filed: July 1, 2021
    Date of Patent: February 11, 2025
    Assignee: MPRD LTD
    Inventors: James Vincent, Ali Ramezani, Michele Cuppini
  • Patent number: 12201817
    Abstract: A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.
    Type: Grant
    Filed: May 9, 2022
    Date of Patent: January 21, 2025
    Assignee: Becton, Dickinson and Company
    Inventors: Richard James Vincent Avery, Malcolm Stanley Boyd, Oliver Charles Gazeley, Gareth James Lewis, David Aubrey Plumptre, James Alexander Senior
  • Publication number: 20250000555
    Abstract: Systems and methods of operating a tower extender in conjunction with a bone anchor housing can comprise positioning a plurality of deflectable members of a distal end of the tower extender proximate the bone anchor housing, pushing the distal end of the tower extender into engagement with the bone anchor housing to flex the plurality of deflectable members around the bone anchor housing to attach the tower extender relative to the bone anchor housing, rotating a knob to lock the plurality of deflectable members from deflecting away from the bone anchor housing, performing a portion of a surgical procedure with the tower extender, rotating the knob to deflect the plurality of deflectable members away from the bone anchor housing and pulling the tower extender away from the bone anchor housing.
    Type: Application
    Filed: September 11, 2024
    Publication date: January 2, 2025
    Inventors: Douglas Brooke, Heidi Farmer, Guillaume Quetier, James Vincent Eaton
  • Patent number: 12167876
    Abstract: Systems and methods of operating a tower extender in conjunction with a bone anchor housing can comprise positioning a plurality of deflectable members of a distal end of the tower extender proximate the bone anchor housing, pushing the distal end of the tower extender into engagement with the bone anchor housing to flex the plurality of deflectable members around the bone anchor housing to attach the tower extender relative to the bone anchor housing, rotating a knob to lock the plurality of deflectable members from deflecting away from the bone anchor housing, performing a portion of a surgical procedure with the tower extender, rotating the knob to deflect the plurality of deflectable members away from the bone anchor housing and puling the tower extender away from the bone anchor housing.
    Type: Grant
    Filed: August 12, 2022
    Date of Patent: December 17, 2024
    Assignee: Zimmer Biomet Spine, Inc.
    Inventors: Douglas Brooke, Heidi Farmer, Guillaume Quetier, James Vincent Eaton
  • Patent number: 12151087
    Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.
    Type: Grant
    Filed: December 28, 2021
    Date of Patent: November 26, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Christian Rehbein, Samuel Steel, Anthony Paul Morris, Matthew Meredith Jones, Robert Veasey, Richard James Vincent Avery, William Marsh
  • Patent number: 12133666
    Abstract: A reducer comprises a reducing shaft for engaging a stabilization member, a reducer body for engaging a pedicle screw extender and receiving the reducing shaft along an axis, and one or more of a three-pawl clutch mechanism, a three-stage locking mechanism and a closure mechanism. The clutch mechanism comprises a clutch housing comprising a central passage into which the reducing shaft extends and ports intersecting the central passage, a clutch knob surrounding the clutch housing, and clutch pawls disposed within the ports. The locking mechanism attaches the reducer body to the pedicle screw extender and comprises a first pivoting lever comprising a toothed end, a second pivoting lever comprising a socket for engaging the tooth, and a protrusion configured to engage the pedicle screw extender. The closure mechanism comprises a driver shaft extending through the reducing shaft and a biasing element to bias the driver shaft to a retracted position.
    Type: Grant
    Filed: August 12, 2022
    Date of Patent: November 5, 2024
    Assignee: Zimmer Biomet Spine, Inc.
    Inventors: Douglas Brooke, Heidi Farmer, Guillaume Quetier, James Vincent Eaton, Larry T. Khoo
  • Patent number: 12119639
    Abstract: An integrated circuit (IC) heater circuit comprises a drive circuit configured to increase the temperature of the IC when consuming power; a temperature sensor coupled to a control node of the drive circuit to activate and deactivate the drive circuit to provide an ambient temperature for the IC, wherein current of the temperature sensor varies with temperature; and a control circuit coupled to the temperature sensor and configured to adjust variation in the temperature sensitivity of the current of the temperature sensor.
    Type: Grant
    Filed: June 26, 2023
    Date of Patent: October 15, 2024
    Assignee: Analog Devices International Unlimited Company
    Inventors: Aref Kahaei, James Vincent Sousae, Carl T. Nelson, Robert Dobkin
  • Publication number: 20240327197
    Abstract: A horse whip (1) comprising a handle portion (2) and a contact portion (3), wherein the contact portion comprises a substantially cylindrical portion at a far end region and a round tapered portion adjacent to said substantially cylindrical portion, which round tapered portion tapers away from the substantially cylindrical portion.
    Type: Application
    Filed: November 7, 2023
    Publication date: October 3, 2024
    Inventors: Robert Paul Victor LeMieux, James Vincent Crowley
  • Publication number: 20240228948
    Abstract: Materials and methods to control a nutrient feed in a cell culture process is provided. A sample is received from a bioreactor comprising a cell culture. A viable cell density and a residual nutrient measurement are determined from the received sample. A daily nutrient feeding target is calculated based on the viable cell density and the residual nutrient measurement. The nutrient is fed to the bioreactor according to the calculated daily nutrient feeding target.
    Type: Application
    Filed: October 16, 2020
    Publication date: July 11, 2024
    Applicant: JANSSEN BIOTECH, INC.
    Inventors: James Vincent PRICE, Stefanie BERGES-VORSANGER, Amalie LEVY, Steven SAVAGE, Abbey WEITH
  • Publication number: 20240216266
    Abstract: A topical probiotic delivery system comprised of (a) at least one quiescent desiccated probiotic, (b) at least one wax, and (c) at least one polymer having a plurality of ionic or ionizable pendant groups.
    Type: Application
    Filed: June 14, 2022
    Publication date: July 4, 2024
    Applicant: Jeen International Corp
    Inventors: James Vincent Gruber, Juan R. Mateu, Adam Perle, Jed Riemer
  • Patent number: 12017053
    Abstract: A method and system for detecting a limit of use of a medical device is disclosed. The method includes starting a timer of a medical device when said medical device is used for the first time, detecting the limit of use of the medical device and indicating the limit of use of the medical device. The limit of use is reached when at least one of a first criterion and a second criterion is met, wherein the first criterion is that the timer reaches or exceeds a time limit and wherein the second criterion is that at least one operation of a drive train of said medical device reaches or exceeds a limit.
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: June 25, 2024
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Ilona Eggert, Michael Caspers, Richard James Vincent Avery, Shane Alistair Day
  • Publication number: 20240132835
    Abstract: Materials and methods to control a nutrient feed in a cell culture process is provided. A sample is received from a bioreactor comprising a cell culture. A viable cell density and a residual nutrient measurement are determined from the received sample. A daily nutrient feeding target is calculated based on the viable cell density and the residual nutrient measurement. The nutrient is fed to the bioreactor according to the calculated daily nutrient feeding target.
    Type: Application
    Filed: October 15, 2020
    Publication date: April 25, 2024
    Applicant: JANSSEN BIOTECH, INC.
    Inventors: James Vincent PRICE, Stefanie BERGES-VORSANGER, Amalie LEVY, Steven SAVAGE, Abbey WEITH
  • Patent number: 11948438
    Abstract: An event detection unit (EDU) for detecting an explosive event is provided. The EDU includes different types of sensors for measuring characteristics of an explosive event. The EDU includes an event notification component. The EDU also includes a processor that receives a measurement from the sensors and generates a combined non-event probability and a combined event probability based on that measurement that indicates a likelihood that an explosive event has not occurred or has occurred. The processor determines whether an explosive event has occurred based on the non-event probabilities and event probabilities. When an explosive event has been determined to occur, the processor directs the event notification component to output a notification that an explosive event has occurred.
    Type: Grant
    Filed: November 30, 2022
    Date of Patent: April 2, 2024
    Assignees: Lawrence Livermore National Security, LLC
    Inventors: James Vincent Candy, Karl Albert Fisher, Christopher Roland Candy
  • Publication number: 20240094227
    Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.
    Type: Application
    Filed: October 12, 2023
    Publication date: March 21, 2024
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
  • Patent number: 11904141
    Abstract: A coding system for a drug reservoir, where the drug reservoir is intended for use with a reservoir holder of a drug delivery device. The coding system includes a collar fitted around the drug reservoir. The collar includes a coding feature that is configured to pass through a corresponding coding feature provided by the reservoir holder of the drug delivery device.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: February 20, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Richard James Vincent Avery, Joseph Butler
  • Patent number: 11854333
    Abstract: Existing currency validation (CVAL) devices, systems, and methods are too slow, costly, intrusive, and/or bulky to be routinely used in common transaction locations (e.g., at checkout, at an automatic teller machine, etc.). Presented herein are devices, systems, and methods to facilitate optical validation of documents, merchandise, or currency at common transaction locations and to do so in an obtrusive and convenient way. More specifically, the present invention embraces a validation device that may be used alone or integrated within a larger system (e.g., point of sale system, kiosk, etc.). The present invention also embraces methods for currency validation using the validation device, as well as methods for improving the quality and consistency of data captured by the validation device for validation.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: December 26, 2023
    Assignee: Hand Held Products, Inc.
    Inventors: Erik Van Horn, Gennady Germaine, Christopher Allen, David J. Ryder, Paul Poloniewicz, Kevin Saber, Sean Philip Kearney, Edward Hatton, Edward C. Bremer, Michael Vincent Miraglia, Robert Pierce, William Ross Rapoport, James Vincent Guiheen, Chirag Patel, Patrick Anthony Giordano, Timothy Good, Gregory M. Rueblinger