Patents by Inventor James W. Darnowski

James W. Darnowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR TREATING BREAST CANCER AND OVARIAN CANCER
    Publication number: 20120237502
    Abstract: The present invention relates to a method for the prevention or treatment of certain breast cancers or ovarian cancer comprising administering to a patient in need thereof of a therapeutically effective amount of a 17,20-lyase inhibitor, wherein the breast cancer or ovarian cancer is estrogen receptor (ER) negative.
    Type: Application
    Filed: November 18, 2011
    Publication date: September 20, 2012
    Applicant: Takeda Pharmaceutical Company Limited
    Inventor: James W. Darnowski
  • Drug cominbations containing AZT
    Patent number: 6365578
    Abstract: Combinations of 3′-azido-3′-deoxythymidine (AZT) with 5-fluorouracil (FUra) or its precursor 5-fluoro-2′-deoxyuridine (FUDR) or methoxtrexate (MTX) exhibit increased cytotoxicity and increased therapeutic index in treatment of carcinomas.
    Type: Grant
    Filed: July 6, 1993
    Date of Patent: April 2, 2002
    Assignee: Roger Williams General Hospital
    Inventors: Paul Calabresi, James W. Darnowski
  • Drug combinations containing AZT
    Patent number: 5116823
    Abstract: Combinations of 3'-azido-3'-deoxythymidine (AZT) with 5-fluorouracil (FUra) or its precursor 5-fluoro-2'-deoxyuridine (FUDR) or methoxtrexate (MTX) exhibit increased cytotoxicity and increased therapeutic index in treatment of carcinomas.
    Type: Grant
    Filed: February 27, 1990
    Date of Patent: May 26, 1992
    Assignee: Roger Williams General Hospital
    Inventors: Paul Calabresi, James W. Darnowski
  • Reduction of the severity of 3'-azido-3'-deoxythymidine-induced anemia using a combination of benzylacyclouridine and dipyridamole
    Patent number: 4950466
    Abstract: The invention is directed to a method of inhibiting anemia caused by the administration of AZT to a patient which comprises administering to said patient an effective anemia-inhibiting amount of a combination of dipyridamole and 5-benzylacyclouridine. The invention is further directed to a pharmaceutical composition comprising as the active pharmaceutical agent a combination of dipyridamole and 5-benzylacyclouridine in association with a pharmaceutically acceptable carrier or diluent.
    Type: Grant
    Filed: June 22, 1988
    Date of Patent: August 21, 1990
    Inventors: Paul Calabresi, James W. Darnowski, Michael C. Wiemann