Patents by Inventor James W. Edinger

James W. Edinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120225484
    Abstract: The present invention provides compositions comprising human placental telopeptide collagen, methods of preparing the compositions, methods of their use and kits comprising the compositions. The compositions, kits and methods are useful, for example, for augmenting or replacing tissue of a mammal.
    Type: Application
    Filed: May 9, 2012
    Publication date: September 6, 2012
    Inventors: Mohit Bhatia, Christ Lugo, Qian Ye, James W. Edinger
  • Publication number: 20120201787
    Abstract: Provided herein are methods of treating spinal cord and traumatic brain injuries using cells from amnion, and populations of such cells, referred to herein as “amnion derived adherent cells” (“AMDACs”).
    Type: Application
    Filed: December 15, 2011
    Publication date: August 9, 2012
    Inventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Vladimir Jankovic, Aleksandr Kaplunovsky, Kristen Labazzo, Eric Law, Bitao Liang
  • Patent number: 8216566
    Abstract: The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations.
    Type: Grant
    Filed: January 14, 2010
    Date of Patent: July 10, 2012
    Assignee: Anthrogenesis Corporation
    Inventors: Casper Paludan, James W. Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri
  • Publication number: 20120164114
    Abstract: Provided herein are methods of using amnion derived adherent cells, and populations of, and compositions comprising, such cells, in the modulation of an immune response. In various embodiments, the immune response is graft-versus-host disease, an allergy, asthma, or an immune-related disease or disorder, e.g., an autoimmune disease.
    Type: Application
    Filed: December 15, 2011
    Publication date: June 28, 2012
    Inventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Vladimir Jankovic, Bitao Liang
  • Publication number: 20120156230
    Abstract: Provided herein are methods of treatment of individuals having an injury to the central nervous system, such as a spinal cord injury or a traumatic brain injury, using placental stem cells and placental multipotent stem cells described herein, and populations of such placental cells.
    Type: Application
    Filed: December 15, 2011
    Publication date: June 21, 2012
    Inventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Vladimir Jankovic, Aleksandr Kaplunovsky, Kristen Labazzo, Eric Law, Bitao Liang
  • Publication number: 20110311491
    Abstract: Provided herein are compositions and methods of treating individuals having sarcoidosis or a sarcoidosis-related disease or disorder, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein. Also provided herein are kits comprising said cells or a composition thereof.
    Type: Application
    Filed: April 6, 2011
    Publication date: December 22, 2011
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: James W. EDINGER, Steven Alan FISCHKOFF, Aleksander FRANCKI, Vladimir JANKOVIC, Bitao LIANG, Philippe MARTIN, Cynthia RAY, Xiaokui ZHANG
  • Publication number: 20110306755
    Abstract: The present invention provides compositions comprising human placental telopeptide collagen, methods of preparing the compositions, methods of their use and kits comprising the compositions. The compositions, kits and methods are useful, for example, for augmenting or replacing tissue of a mammal.
    Type: Application
    Filed: August 18, 2011
    Publication date: December 15, 2011
    Inventors: Mohit Bhatia, Chris Lugo, Qian Ye, James W. Edinger
  • Publication number: 20110280845
    Abstract: Provided herein are methods of treatment of individuals having an immune-related disease, disorder or condition, for example, inflammatory bowel disease, graft-versus-host disease, multiple sclerosis, rheumatoid arthritis, psoriasis, lupus erythematosus, diabetes, mycosis fungoides (Alibert-Bazin syndrome), or scleroderma using placental stem cells or umbilical cord stem cells.
    Type: Application
    Filed: May 13, 2011
    Publication date: November 17, 2011
    Inventors: James W. EDINGER, Robert J. Hariri, Jia-Lun Wang, Qian Ye, Herbert Faleck
  • Publication number: 20110280843
    Abstract: Provided herein are methods of treatment of individuals having an immune-related disease, disorder or condition, for example, inflammatory bowel disease, graft-versus-host disease, multiple sclerosis, rheumatoid arthritis, psoriasis, lupus erythematosus, diabetes, mycosis fungoides (Alibert-Bazin syndrome), or scleroderma using placental stem cells or umbilical cord stem cells.
    Type: Application
    Filed: May 13, 2011
    Publication date: November 17, 2011
    Inventors: James W. EDINGER, Robert J. Hariri, Jia-Lun Wang, Qian Ye, Herbert Faleck
  • Publication number: 20110250182
    Abstract: Provided herein are methods of treating individuals having diseases or disorders of the circulatory system, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein, and populations of such placental cells. The invention also provides methods of angiogenesis using such cells or populations of cells comprising such cells.
    Type: Application
    Filed: April 6, 2011
    Publication date: October 13, 2011
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: Stewart ABBOT, James W. EDINGER, Aleksandar FRANCKI, Robert J. HARIRI, Vladimir JANKOVIC, Aleksandr KAPLUNOVSKY, Kristen LABAZZO, Eric LAW, Neerav D. PADLIYA, Jennifer PAREDES, Jia-Lun WANG
  • Publication number: 20110250185
    Abstract: The present invention provides methods of suppression of tumor cell proliferation and tumor growth using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of tumor suppression, and compositions comprising such cells and cell populations.
    Type: Application
    Filed: June 20, 2011
    Publication date: October 13, 2011
    Inventors: Casper Paludan, James W. Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri, Qian Ye
  • Patent number: 7993918
    Abstract: The present invention provides methods of suppression of tumor cell proliferation and tumor growth using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of tumor suppression, and compositions comprising such cells and cell populations.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: August 9, 2011
    Assignee: Anthrogenesis Corporation
    Inventors: Casper Paludan, James W. Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri, Qian Ye
  • Publication number: 20100291679
    Abstract: The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem cell collection composition comprising an apoptosis inhibitor and, optionally, an enzyme such as a protease or mucolytic enzyme, vasodilator, necrosis inhibitor, oxygen-carrying perfluorocarbon, or an organ preserving compound. The invention provides methods of using the stem cell collection composition to collect stem cells and to preserve populations of stem cells.
    Type: Application
    Filed: July 29, 2010
    Publication date: November 18, 2010
    Inventors: James W. Edinger, Mohammad Heidaran, Wolfgang Hofgartner
  • Publication number: 20100124569
    Abstract: Provided herein are novel angiogenic cells from amnion, referred to as amnion derived adherent cells, and populations of, and compositions comprising, such cells. Further provided herein are methods of obtaining such cells and methods of using the cells in the treatment of individuals.
    Type: Application
    Filed: November 19, 2009
    Publication date: May 20, 2010
    Inventors: Stewart ABBOT, James W. Edinger, Aleksandar Francki, Aleksandr Kaplunovsky, Vladimir Jankovic, Kristen Labazzo, Eric Law, Neerav D. Padliya, Jennifer Paredes, Jia-Lun Wang
  • Publication number: 20080226595
    Abstract: Provided herein are methods of treatment of individuals having an immune-related disease, disorder or condition, for example, inflammatory bowel disease, graft-versus-host disease, multiple sclerosis, rheumatoid arthritis, psoriasis, lupus erythematosus, diabetes, mycosis fungoides (Alibert-Bazin syndrome), or scleroderma using placental stem cells or umbilical cord stem cells.
    Type: Application
    Filed: February 12, 2008
    Publication date: September 18, 2008
    Inventors: James W. Edinger, Robert J. Hariri, Jia-Lun Wang, Qian Ye, Herbert Faleck
  • Publication number: 20080213228
    Abstract: Provided herein are methods of using adherent placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. Also provided herein are methods of differentiating the placental stem cells. Further provided herein are methods of using the placental stem cells to formulate implantable or injectable compositions suitable for administration to a subject. Still further provided herein are provides methods for treating bone defects with stem cells and compositions comprising stem cells.
    Type: Application
    Filed: October 23, 2007
    Publication date: September 4, 2008
    Applicant: Anthrogenesis Corporation
    Inventors: James W. Edinger, Robert J. Hariri, Jia-Lun Wang, Qian Ye, Kristen S. Labazzo, Marian Pereira, Sascha Dawn Abramson
  • Publication number: 20080206343
    Abstract: Provided herein are methods and compositions for the production of hepatocytes from placenta stem cells. Further provided herein is the use of such hepatocytes in the treatment of, and intervention in, for example, trauma, inflammation, and degenerative disorders of the liver. Also provided herein are compositions and methods relating to combinations of nanofibrous scaffolds and adherent placental stem cells and methods of using the same in cartilage repair. Finally, provided herein are compositions and methods relating to nonadherent, CD34+CD45? stem cells from placenta.
    Type: Application
    Filed: February 12, 2008
    Publication date: August 28, 2008
    Inventors: James W. Edinger, Robert J. Hariri, Jia-Lun Wang, Qian Ye, Marian Pereira, Sascha Dawn Abramson, Kristen S. Labazzo
  • Publication number: 20080181935
    Abstract: The present invention provides compositions comprising human placental telopeptide collagen, methods of preparing the compositions, methods of their use and kits comprising the compositions. The compositions, kits and methods are useful, for example, for augmenting or replacing tissue of a mammal.
    Type: Application
    Filed: October 9, 2007
    Publication date: July 31, 2008
    Inventors: Mohit Bhatia, Chris Lugo, Qian Ye, James W. Edinger
  • Publication number: 20080152624
    Abstract: The present invention provides methods of suppression of tumor cell proliferation and tumor growth using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of tumor suppression, and compositions comprising such cells and cell populations.
    Type: Application
    Filed: August 3, 2007
    Publication date: June 26, 2008
    Inventors: Casper Paludan, James W. Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri, Qian Ye