Patents by Inventor James W. Polarek

James W. Polarek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCING DOUBLE-CROSSLINKED COLLAGEN
    Publication number: 20110207671
    Abstract: The present invention relates to double-crosslinked collagen materials, methods for preparing double-crosslinked collagen materials, and methods of using double-crosslinked
    Type: Application
    Filed: August 21, 2009
    Publication date: August 25, 2011
    Applicant: FibroGen, Inc.
    Inventors: Robert C. Chang, David R. Olsen, Jame W. Polarek, Kim E. Williams
  • Recombinant gelatins
    Publication number: 20090143568
    Abstract: The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.
    Type: Application
    Filed: May 15, 2008
    Publication date: June 4, 2009
    Applicant: FibroGen, Inc.
    Inventors: Robert C. Chang, Kari Kivirikko, Thomas B. Neff, David R. Olsen, James W. Polarek
  • Recombinant gelatins
    Patent number: 7393928
    Abstract: The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.
    Type: Grant
    Filed: May 27, 2005
    Date of Patent: July 1, 2008
    Assignee: FibroGen, Inc.
    Inventors: Robert C. Chang, Kari I. Kivirikko, Thomas B. Neff, David R. Olsen, James W. Polarek
  • Recombinant gelatins
    Patent number: 6992172
    Abstract: The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.
    Type: Grant
    Filed: November 10, 2000
    Date of Patent: January 31, 2006
    Assignee: FibroGen, Inc.
    Inventors: Robert C. Chang, Kari I. Kivirikko, Thomas B. Neff, David R. Olsen, James W. Polarek
  • Bovine collagens and gelatins
    Publication number: 20040018592
    Abstract: The present invention provides animal collagens and gelatins and compositions thereof, and methods of producing the same.
    Type: Application
    Filed: March 26, 2003
    Publication date: January 29, 2004
    Applicant: FibroGen, Inc.
    Inventors: Marcum P. Bell, Thomas B. Neff, James W. Polarek, Todd W. Seeley
  • Porcine collagens and gelatins
    Publication number: 20040005663
    Abstract: The present invention provides animal collagens and gelatins and compositions thereof, and methods of producing the same.
    Type: Application
    Filed: March 26, 2003
    Publication date: January 8, 2004
    Inventors: Marcum P. Bell, Thomas B. Neff, James W. Polarek, Todd W. Seeley
  • Recombinant gelatins in vaccines
    Publication number: 20030064074
    Abstract: The present invention relates to vaccines comprising recombinant gelatin, to methods of producing and using such vaccines, and to vaccination kits.
    Type: Application
    Filed: August 30, 2002
    Publication date: April 3, 2003
    Inventors: Robert C. Chang, Kari I. Kivirikko, Thomas B. Neff, David R. Olsen, James W. Polarek
  • Type III collagen compositions
    Publication number: 20030008831
    Abstract: Polymerized type I collagen based compositions for medical use as vascular sealants and wound dressings, the preparation thereof, are described. Prior to polymerization, the collagen monomers are prepared recombinantly whereby chemical modifications of the collagen are not needed to form such monomers. The type I collagen and/or type III collagen compositions, which include gelatin comprised of type I collagen and type III collagen, are useful as medical adhesives for bonding soft tissues and as sealants for a variety of medical uses. In a further aspect of the present invention, the polymerized type I collagen and/or type III collagen compositions include agents which induce wound healing or provide for additional beneficial characteristics desired in a tissue sealant or wound dressing. The compositions of the present invention are also useful in non-adhesive form.
    Type: Application
    Filed: August 2, 2002
    Publication date: January 9, 2003
    Inventors: Chunlin Yang, James W. Polarek, Thomas B. Neff
  • COLLAGEN TYPE I AND TYPE III HEMOSTATIC COMPOSITIONS FOR USE AS A VASCULAR SEALANT AND WOUND DRESSING
    Publication number: 20020015724
    Abstract: Polymerized type I and/or III collagen based compositions for medical use as vascular sealants and wound dressings, and the preparation thereof, are described. Prior to polymerization, the collagen monomers are prepared recombinantly whereby chemical modifications of the collagen are not needed to form such monomers. The type I and/or III collagen compositions, which include gelatin comprised of type I and type III collagens, are useful as medical adhesives for bonding soft tissues and as sealants for a variety of medical uses. In a further aspect of the present invention, the polymerized type I and/or III collagen compositions include agents which induce wound healing or provide for additional beneficial characteristics desired in a tissue sealant or wound dressing. The compositions of the present invention are also useful in non-adhesive form.
    Type: Application
    Filed: August 10, 1999
    Publication date: February 7, 2002
    Inventors: CHUNLIN YANG, JAMES W. POLAREK, THOMAS B. NEFF
  • Polypeptide-polymer conjugates active in wound healing
    Patent number: 5955578
    Abstract: A conjugate of a synthetic polypeptide containing RGD or (dR) GD and a biodegradable polymer, such as hyaluronic acid or chondroitin sulfate is disclosed. Methods of making the conjugate and using it to aid wound healing by providing a temporary matrix are disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 21, 1999
    Assignee: La Jolla Cancer Research Foundation
    Inventors: Michael D. Pierschbacher, James W. Polarek, Marianne P. Petrica, Erkki I. Ruoslahti
  • Immobilization of peptides to hyaluronate
    Patent number: 5677276
    Abstract: The present invention provides novel conjugates of a synthetic polypeptide containing RGD or (dR)GD and a biodegradable polymer, hyaluronate. The conjugates are prepared by any one of three different methods provided by the present invention: (1) an epoxide method (2) a sodium periodate method, and (3) a tresyl chloride method. The conjugates prepared by these methods are useful to aid in wound healing and tissue regeneration by providing a temporary matrix for tissue repair. The invention also provides novel RGD-peptides.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: October 14, 1997
    Assignee: La Jolla Cancer Research Foundation
    Inventors: Kenneth T. Dickerson, James R. Glass, Lin-Shu Liu, James W. Polarek, William S. Craig, Daniel G. Mullen, Soan Cheng