Patents by Inventor James W. Ringer
James W. Ringer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10570114Abstract: Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.Type: GrantFiled: July 26, 2018Date of Patent: February 25, 2020Assignee: Dow AgroSciences LLCInventors: Jason S. Fisk, Xiaoyong Li, Mark Muehlfeld, Robert S. Bauman, Jossian Oppenheimer, Siyu Tu, Mark A. Nitz, Reetam Chakrabarti, Shawn D. Feist, James W. Ringer, Ronald B. Leng
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Patent number: 10544121Abstract: Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.Type: GrantFiled: July 26, 2018Date of Patent: January 28, 2020Assignee: Dow AgroSciences LLCInventors: Jason S. Fisk, Xiaoyong Li, Mark Muehlfeld, Robert S. Bauman, Jossian Oppenheimer, Siyu Tu, Mark A. Nitz, Reetam Chakrabarti, Shawn D. Feist, James W. Ringer, Ronald B. Leng
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Publication number: 20180334444Abstract: Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.Type: ApplicationFiled: July 26, 2018Publication date: November 22, 2018Applicant: Dow AgroSciences LLCInventors: Jason S. Fisk, Xiaoyong Li, Mark Muehlfeld, Robert S. Bauman, Jooossian Oppenheimer, Siyu Tu, Mark A. Nitz, Reetam Chakrabarti, Shawn D. Feist, James W. Ringer, Ronald B. Leng
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Publication number: 20180334445Abstract: Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.Type: ApplicationFiled: July 26, 2018Publication date: November 22, 2018Applicant: Dow AgroSciences LLCInventors: Jason S. F, Xiaoyong Li, Mark Muehlfeld, Robert S. Bauman, Jossian Oppenheimer, Siyu Tu, Mark A. Nitz, Reetam Chakrabarti, Shawn D. Feist, James W. Ringer, Ronald B. Leng
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Patent number: 10087164Abstract: Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This invention was expanded to include synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.Type: GrantFiled: May 19, 2017Date of Patent: October 2, 2018Assignee: Dow AgroSciences LLCInventors: Jason S. Fisk, Xiaoyong Li, Mark Muehlfeld, Robert S. Bauman, Jossian Oppenheimer, Siyu Tu, Mark A. Nitz, Reetam Chakrabarti, Shawn D. Feist, James W. Ringer, Ronald B. Leng
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Publication number: 20170334878Abstract: Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalky and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This invention was expanded to include synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.Type: ApplicationFiled: May 19, 2017Publication date: November 23, 2017Applicant: Dow AgroSciences LLCInventors: Jason S. Fisk, Xiaoyong Li, Mark Muehlfeld, Robert S. Bauman, Jossian Oppenheimer, Siyu Tu, Mark A. Nitz, Reetam Chakrabarti, Shawn D. Feist, James W. Ringer, Ronald B. Leng
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Patent number: 8318834Abstract: An epoxy resin reactive diluent composition comprises an epoxy resin diluent (A) and a resin compound (B), wherein the epoxy resin diluent (A) comprises a cis, trans-1,3- and -1,4-cyclohexanedimethylether moiety; and wherein the resin compound (B) comprises one or more epoxy resins other than the epoxy resin diluent (A). A curable epoxy resin composition comprises the epoxy resin reactive diluent composition and a curing agent and/or curing catalyst therefore. A cured epoxy resin is prepared by curing the curable epoxy resin composition.Type: GrantFiled: May 4, 2009Date of Patent: November 27, 2012Assignee: Dow Global Technologies LLCInventors: Robert E. Hefner, Jr., John W. Hull, Jr., James W. Ringer, John N. Argyropoulos
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Publication number: 20110054056Abstract: Thermoset polyurethanes comprising a cis, trans-1,3- and -1,4-cyclohexanedimethylether moiety. Adducts of epoxy resins comprising a cis, trans-1,3- and -1,4-cyclohexanedimethylether moiety are used to react with a polyisocyanate to produce the thermoset polyurethanes.Type: ApplicationFiled: May 4, 2009Publication date: March 3, 2011Inventors: Robert E. Hefner, JR., James W. Ringer
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Publication number: 20110046266Abstract: An epoxy resin reactive diluent composition comprises an epoxy resin diluent (A) and a resin compound (B), wherein the epoxy resin diluent (A) comprises a cis, trans-1,3- and -1,4-cyclohexanedimethylether moiety; and wherein the resin compound (B) comprises one or more epoxy resins other than the epoxy resin diluent (A). A curable epoxy resin composition comprises the epoxy resin reactive diluent composition and a curing agent and/or curing catalyst therefore. A cured epoxy resin is prepared by curing the curable epoxy resin composition.Type: ApplicationFiled: May 4, 2009Publication date: February 24, 2011Inventors: Robert E. Hefner, JR., John W. Hull, JR., James W. Ringer, John N. Argyropoulos
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Publication number: 20110039982Abstract: Epoxy resins comprising a cis, trans-1,3- and -1,4-cyclohexanedimethylether moiety and processes for preparing the epoxy resins. The process of preparation of the epoxy resins comprises reacting (a) a mixture of a cis-1,3-cyclohexanedimethanol, a trans-1,3-cyclohexanedimethanol, a cis-1,4-cyclohexanedimethanol, and a trans-1,4-cyclohexanedimethanol, (b) an epihalohydrin, (c) a basic acting substance, (d) optionally, a solvent, (e) optionally, a catalyst, and/or (f) optionally, a dehydrating agent. The process may be a slurry epoxidation process, an anhydrous epoxidation process, or a Lewis acid catalyzed coupling and epoxidation process.Type: ApplicationFiled: May 4, 2009Publication date: February 17, 2011Inventors: Robert E. Hefner, JR., John W. Hull, JR., James W. Ringer, John N. Argyropoulos
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Publication number: 20110040046Abstract: An adduct comprises at least one reaction product of (i) an epoxy resin material (A) and (ii) a reactive compound (B). The epoxy resin material (A) comprises a cis, trans-1,3- and -1,4-cyclohexanedimethylether moiety and the reactive compound (B) comprises a compound having two or more reactive hydrogen atoms per molecule, wherein the reactive hydrogen atoms are reactive with epoxide groups. A curable epoxy resin composition comprises the adduct described above. A cured epoxy resin is prepared by a process of curing the curable epoxy resin composition.Type: ApplicationFiled: May 4, 2009Publication date: February 17, 2011Inventors: Robert E. Hefner, JR., James W. Ringer
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Patent number: 6921834Abstract: In general the present invention relates to a continuous process for manufacturing (N-phosphonomethyl) glycine, glyphosate, by the catalyzed oxidation of N-phosphonomethyliminodiacetic acid. Glyphosate can be provided in high yield and in a cost efficient process by minimizing the competing side reactions and by-products. The process includes conducting the oxidation reaction and selecting an appropriate catalyst to maximize the rate of the oxidation of N-phosphonomethyliminodiacetic acid while at the same time minimizing the rate of oxidation of glyphosate in the same reaction.Type: GrantFiled: November 21, 2002Date of Patent: July 26, 2005Assignee: Dow Agrosciences LLCInventors: Daniel A. Hickman, James W. Ringer
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Publication number: 20030229245Abstract: In general the present invention relates to a continuous process for manufacturing (N-phosphonomethyl) glycine, glyphosate, by the catalyzed oxidation of N-phosphonomethyliminodiacetic acid. Glyphosate can be provided in high yield and in a cost efficient process by minimizing the competing side reactions and by-products. The process includes conducting the oxidation reaction and selecting an appropriate catalyst to maximize the rate of the oxidation of N-phosphonomethyliminodiacetic acid while at the same time minimizing the rate of oxidation of glyphosate in the same reaction.Type: ApplicationFiled: November 21, 2002Publication date: December 11, 2003Inventors: Daniel A. Hickman, James W. Ringer
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Publication number: 20010008948Abstract: Aliphatic primary alcohols, including aliphatic primary alcohols possessing one or more oxygen, nitrogen and/or phosphorus heteroatoms that may be atoms substituting for carbon atoms in the alkyl group or component atoms of substituents on the alkyl group, were converted into salts of carboxylic acids by contacting an alkaline aqueous solution of the primary alcohol with a catalyst comprising cobalt, copper, and at least one of cerium, iron, zinc, and zirconium. Diethanolamine, for example, was converted to sodium iminodiacetate by treatment in an aqueous medium containing sodium hydroxide with a catalyst that was obtained by reducing a mixture of cobalt, copper, and zirconium oxides with hydrogen.Type: ApplicationFiled: February 5, 2001Publication date: July 19, 2001Inventors: James W. Ringer, David C. Molzahn, Dennis A. Hucul
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Patent number: 6229045Abstract: Aliphatic primary alcohols, including aliphatic primary alcohols possessing one or more oxygen, nitrogen and/or phosphorus heteroatoms that may be atoms substituting for carbon atoms in the alkyl group or component atoms of substituents on the alkyl group, were converted into salts of carboxylic acids by contacting an alkaline aqueous solution of the primary alcohol with a catalyst comprising cobalt, copper, and at least one of cerium, iron, zinc, and zirconium. Diethanolamine, for example, was converted to sodium iminodiacetate by treatment in an aqueous medium containing sodium hydroxide with a catalyst that was obtained by reducing a mixture of cobalt, copper, and zirconium oxides with hydrogen.Type: GrantFiled: September 14, 1999Date of Patent: May 8, 2001Assignee: Dow AgroSciences LLCInventors: James W. Ringer, Dennis A. Hucul, David C. Molzahn
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Patent number: 6114580Abstract: N-arylsulfilimine compounds, such as S,S-dimethyl-N-(2,6-dichlorophenyl)sulfilimine, were prepared and found to catalyze the reaction of aromatic sulfonyl chloride compounds, such as 2-chlorosulfonyl-7-fluoro-5-ethoxy[1,2,4]triazolo[1,5-c]pyrimidine, with aromatic amine compounds, such as 2,6-dichloroaniline, to form N-arylarylsulfonamide compounds, such as N-(2,6-dichlorophenyl)-7-fluoro-5-ethoxy[1,2,4]triazolo[1,5-c]pyrimidine-2 -sulfonamide. The aryl moiety of the N-arylsulfilimine catalyst and the aryl moiety of the aromatic amine compound were generally chosen to be identical.Type: GrantFiled: November 13, 1997Date of Patent: September 5, 2000Assignee: Dow AgroSciences LLCInventors: James W. Ringer, Douglas L. Pearson, Carmen A. Scott, Anne P. Wallin
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Patent number: 6066734Abstract: Chloropyrimidine compounds, such as 4,6-dichloro-2-ethoxypyrimidine, were prepared in good yield and good purity from the corresponding hydroxypyrimidine compounds in the absence of organic solvents and with a reduced amount of phosphorus oxychloride by carrying out the reaction in the presence of a trialkylamine compound and phosphorus trichloride. The additions of hydroxypyrimidine compound and trialkylamine compound could be made in segments. The chloropyrimidine compounds produced were recovered in an improved manner by adding chlorine to convert the chlorophosphoric acid by-products and phosphorus trichloride to phosphorus oxychloride, diluting the mixture with additional chloropyrimidine compound and removing the phosphorus oxychloride by distillation, combining the residue with water and a base, distilling the trialkylamine compound from the resulting mixture, and removing the aqueous phase.Type: GrantFiled: December 18, 1998Date of Patent: May 23, 2000Assignee: Dow AgroSciences LLCInventors: Ronald B. Leng, Julie L. Maurer, James W. Ringer
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Patent number: 5973148Abstract: N-arylsulfilimine compounds, such as S,S-dimethyl-N-(2,6-dichlorophenyl)sulfilimine, were prepared and found to catalyze the reaction of aromatic sulfonyl chloride compounds, such as 2-chlorosulfonyl-7-fluoro-5-ethoxy[1,2,4]triazolo[1,5-c]pyrimidine, with aromatic amine compounds, such as 2,6-dichloroaniline, to form N-arylarylsulfonamide compounds, such as N-(2,6-dichlorophenyl)-7-fluoro-5-ethoxy[1,2,4]triazolo[1,5-c]-pyrimidine- 2-sulfonamide. The aryl moiety of the N-arylsulfilimine catalyst and the aryl moiety of the aromatic amine compound were generally chosen to be identical.Type: GrantFiled: December 23, 1998Date of Patent: October 26, 1999Assignee: Dow AgroSciences LLCInventors: James W. Ringer, Carmen A. Scott, Douglas L. Pearson, Anne P. Wallin
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Patent number: 5488109Abstract: 2-Chlorosulfonyl-5-alkoxy[1,2,4]triazolo-[1,5-c]pyrimidine compounds, such as 2-chlorosulfonyl-5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidine, that are useful for the preparation of 5-alkoxy[1,2,4]triazolo [1,5-c]pyrimidine-2-sulfonamide herbicides, were prepared in an improved manner from 5-alkoxy[1,2,4]triazolo [1,5-c]pyrimidine-2(3H)-thione compounds, such as 5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thione, by oxidation with hydrogen peroxide to obtain novel 2,2'-dithiobis(5-alkoxy[1,2,4]triazolo[1,5-c]pyrimidine) compounds, such as 2,2'-dithiobis (5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidine), and subsequent chloroxidation of these intermediate compounds.Type: GrantFiled: November 5, 1993Date of Patent: January 30, 1996Assignee: DowElancoInventors: Thomas A. Olmstead, Michael A. Gonzalez, Jon A. Orvik, Douglas L. Pearson, James W. Ringer, Dawn Shiang, Jimmy J. Tai, Anne P. Wallin
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Patent number: 5214144Abstract: 4-Haloquinazolines can be prepared by the halogenation of the corresponding 4-hydroxyquinazolines with a phosphoryl, thionyl or carbonyl halide in the presence of a catalytically effective amount of a N,N-dialkylformamide. The reaction is catalyzed by the addition of soluble organic halide salts.Type: GrantFiled: October 7, 1991Date of Patent: May 25, 1993Assignee: DowElancoInventors: Jimmy J. Tai, James W. Ringer, Karl L. Krumel, Richard C. Krauss