Abstract: A heat exchanger module configured for use in a vapor compression based climate control system including a suction line heat exchanger having a plurality of stacked plates configured to accommodate two separate fluid flow paths for heat exchange therebetween. The heat exchanger also includes a first inlet for flow of a high pressure subcooled fluid from a condenser to the module along a first fluid flow path, a first outlet for flow of a low pressure superheated fluid from the module to a compressor along a second fluid flow path, a second outlet for flow of the subcooled fluid from the module to an evaporator along a third fluid flow path, and a second inlet for flow of the low pressure superheated fluid from the evaporator to the module along a fourth fluid flow path. The module also includes a port block with a first conduit for the third fluid flow path and a second conduit for the fourth fluid flow path.

Abstract: The invention is directed to an isolated genomic polynucleotide fragment that encodes human soluble (cytosolic) aminopeptidase P, vectors and hosts containing the fragment and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human soluble aminopeptidase P and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments that encode human carboxypeptidase M and human mouse double minute 2 homolog, vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human carboxypeptidase M and human mouse double minute 2 homolog and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments that encode human SNARE YKT6, human glucokinase, human adipocyte enhancer binding protein (AEBP1) and DNA directed 50 kD regulatory subunit (POLD2), vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain SNARE YKT6, human glucokinase, AEBP1 protein and POLD2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments that encode human SNARE YKT6, human glucokinase, human adipocyte enhancer binding protein (AEBP1) and DNA directed 50 kD regulatory subunit (POLD2), vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain SNARE YKT6, human glucokinase, AEBP1 protein and POLD2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments that encode human SNARE YKT6, human glucokinase, human adipocyte enhancer binding protein (AEBP1) and DNA directed 50kD regulatory subunit (POLD2), vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain SNARE YKT6, human glucokinase, AEBP1 protein and POLD2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments that encode human SNARE YKT6, human glucokinase, human adipocyte enhancer binding protein (AEBP1) and DNA directed 50 kD regulatory subunit (POLD2), vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain SNARE YKT6, human glucokinase, AEBP1 protein and POLD2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments that encode human resistin and human syntaxin binding protein 2, vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human resistin and human syntaxin binding protein 2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2, vectors and hosts containing the fragment and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human lipoprotein-associated phospholipase A2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to an isolated genomic polynucleotide fragment that encodes human soluble (cytosolic) aminopeptidase P, vectors and hosts containing the fragment and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human soluble aminopeptidase P and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2, vectors and hosts containing the fragment and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human lipoprotein-associated phospholipase A2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments that encode human SNARE YKT6, human liver glucokinase, human adipocyte enhancer binding protein (AEBP1) and DNA directed 50 kD regulatory subunit (POLD2), vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain SNARE YKT6, human liver glucokinase, AEBP1 protein and POLD2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Abstract: The invention is directed to isolated genomic polynucleotide fragments from the p15 arm of chromosome 11.

Abstract: Disclosed are the human aminopeptidase P cDNA and genomic DNA. Also disclosed is the human aminopeptidase P protein and antibodies reactive with human aminopeptidase P. These molecules, and derivatives of these molecules, are useful for assay for detecting aminopeptidase polymorphisms, protein variants, and activity, and identifying compounds that inhibit expression of aminopeptidase genes and activity of aminopeptidase protein.

Abstract: A fire extinguishing device to reduce or extinguish a fire in a specific localized area such as a room or a hallway within a burning building. A base with a disbursement container fixed to the base is provided to hold an explosive charge and a volume of fire extinguishing agent. When the explosive charge is detonated, the extinguishing agent is forced out of the disbursement container in an upward direction to subsequently shower down upon a fire in the vicinity of the detonated fire extinguishing device to at least in part extinguish the fire in the localized area.

Abstract: There is provided a cylindrical link and armor for electrical, electronic, or fiber-optic cables, hoses, conduits and the like. The armor comprises links which can either rigidly or flexibly interlock and can support their own weight.

Abstract: Novel inhibitors of angiotensin coverting enzyme having the general formula R - A - S - Z are disclosed as potent inhibitors of angiotensin converting enzyme and are useful anti-hypertensive agents.

Abstract: Methods for the alkylation of substituted amines with trifluorate esters is disclosed.

Abstract: Novel inhibitors of angiotensin converting enzyme are disclosed which have the general formula ##STR1## wherein R.sub.1 and/or R.sub.3 form complex amides and imides thereof, R.sub.4 and R.sub.5 form with --N--C-- a 4-6 membered ring structure as described and the other R substituents are selected from a variety of disclosed groups.

Abstract: A new and useful method for assaying proteases, in which an excess of tagged proteinaceous inhibitor of a protease is mixed in solution with a sample containing the protease to form a mixture of a tagged inhibitor-protease complex and free tagged inhibitor. The complex is separated from the tagged inhibitor and the tag measured. Alternatively, anti-protease antibody may be added to bind the complex so that assay specificity and/or separation is enhanced. The method of this invention is applicable to assaying minute quantities of clinically significant proteases e.g. renin, kallikrein, thrombin occurring in serum, plasma, urine and other tissues.