Patents by Inventor James W. Wheeler

James W. Wheeler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240075069
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: August 31, 2023
    Publication date: March 7, 2024
    Inventors: Philip Stewart LOW, Haiyan CHU, Yingjuan June LU, Christopher Paul LEAMON, Leroy W. WHEELER, II, Michael C. JENSEN, James MATTHAEI
  • Patent number: 5262054
    Abstract: The salt passage of a reverse osmosis membrane is increased by: (a) contacting the membrane with ions to form a membrane-ion complex; (b) treating the membrane-ion complex with an aqueous solution of an alkali metal permanganate to form manganese dioxide crystals in the membrane; and (c) dissolving the manganese dioxide crystals. The process can be repeated any number of times to further open the membrane.
    Type: Grant
    Filed: December 30, 1992
    Date of Patent: November 16, 1993
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: James W. Wheeler
  • Patent number: 5141797
    Abstract: An ink jet recording sheet comprising a sheet support, e.g., paper, bearing a surface coating comprising (a) a water soluble organic polymeric binder, (b) a titanium chelate crosslinking agent as defined, and (c) an inorganic filler, the weight ratio of (c) to (a) preferably being about 7 to 1 to about 1 to 2. The ink jet recording sheet is useful for ink jet printing.
    Type: Grant
    Filed: June 6, 1991
    Date of Patent: August 25, 1992
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: James W. Wheeler
  • Patent number: 4724960
    Abstract: A package for containing relatively long and relatively heavy rolls of polymeric film or the like comprising a container of a predetermined size and shape made of corrugated paper board or similar inexpensive materials with one or more fillets of a predetermined size and shape made of corrugated paper board, Styrofoam, foamed plastic or the like suitably affixed to the container at an appropriate place so as to provide a package which has the shape of a rectangular box and has vertical integrity when a plurality of the containers are stacked one upon the other.The container may be a rectangularly shaped box or hollow hexahedron with fillets affixed to the internal surfaces thereof, a tubular shaped cylinder with fillets affixed to the exterior surface thereof or alternatively a triangularly shaped box or hollow pentahedron.
    Type: Grant
    Filed: October 7, 1982
    Date of Patent: February 16, 1988
    Assignee: Ethyl Corporation
    Inventors: Richard W. Goodrum, James W. Wheeler
  • Patent number: 4701398
    Abstract: A new group of cyanine and merocyanine spectral sensitizing dyes based on derivatives of 3-indolizine carboxaldehyde is particularly useful in sensitizing a direct positive silver halide emulsion to orange and red.
    Type: Grant
    Filed: March 14, 1986
    Date of Patent: October 20, 1987
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: James W. Wheeler
  • Patent number: 4614801
    Abstract: A new group of cyanine and merocyanine spectral sensitizing dyes based on derivatives of 3-indolizine carboxaldehyde is particularly useful in sensitizing a direct positive silver halide emulsion to orange and red.
    Type: Grant
    Filed: April 2, 1985
    Date of Patent: September 30, 1986
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: James W. Wheeler
  • Patent number: 4355098
    Abstract: Direct positive photographic elements with improved spectral sensitivity in the green and red portion of the visible spectrum are obtained from emulsions containing a supersensitizing amount of a spectral sensitizing dye (a) having a solution absorption maximum less than 495 nm and the lowest vacant energy band less than -3.7 eV, and a sensitizing amount of a spectral sensitizing dye (b) having a lowest vacant energy band between -3.7 eV and 0.3 eV below the lowest vacant energy band of said spectral sensitizing dye (a) and with the highest occupied energy band between -5.9 eV and 0.3 eV above the highest occupied energy level of dye (a).
    Type: Grant
    Filed: February 11, 1981
    Date of Patent: October 19, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: James W. Wheeler
  • Patent number: 3994090
    Abstract: A marking and splicing aid for cables utilized in the splicing of telephone cables and the like where particular wires of cables to be spliced must be joined. The aid employs a multiplicity of color-coded wires each having opposite ends and a binder interconnecting the wires intermediate their opposite ends in predetermined ordered arrangement, said binder bearing color and numerical indicia corresponding to the color coding and ordered arrangement of the wires.
    Type: Grant
    Filed: August 18, 1975
    Date of Patent: November 30, 1976
    Inventor: James W. Wheeler