Patents by Inventor James W. Yockman

James W. Yockman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cleavable modifications to reducible poly(amido ethylenimine)s to enhance nucleotide delivery
    Patent number: 8829109
    Abstract: Improved poly(amido ethylenimine) copolymers for gene delivery are disclosed. One illustrative embodiment includes polyethylene glycol (PEG) covalently bonded to a branched poly(triethyenetetramine/cystamine bisacrylamide) copolymer (poly(TETA/CBA)). The polyethylene glycol can be linear or branched. Another illustrative embodiment includes an RGD peptide covalently bonded to the poly(TETA/CBA)-PEG conjugate. Still another illustrative embodiment includes a method of using these compositions for transfecting a cell with a nucleic acid.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: September 9, 2014
    Assignee: University of Utah Research Foundation
    Inventors: James W. Yockman, Jonathan Brumbach, Lane V. Christensen, Sung Wan Kim
  • CLEAVABLE MODIFICATIONS TO REDUCIBLE POLY(AMIDO ETHYLENIMINE)S TO ENHANCE NUCLEOTIDE DELIVERY
    Publication number: 20090142842
    Abstract: Improved poly(amido ethylenimine) copolymers for gene delivery are disclosed. One illustrative embodiment includes polyethylene glycol (PEG) covalently bonded to a branched poly(triethyenetetramine/cystamine bisacrylamide) copolymer (poly(TETA/CBA)). The polyethylene glycol can be linear or branched. Another illustrative embodiment includes an RGD peptide covalently bonded to the poly(TETA/CBA)-PEG conjugate. Still another illustrative embodiment includes a method of using these compositions for transfecting a cell with a nucleic acid.
    Type: Application
    Filed: November 7, 2008
    Publication date: June 4, 2009
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: James W. Yockman, Jonathan Brumbach, Lane V. Christensen, Sung Wan Kim