Abstract: A medical device may comprise a sheath configured to be inserted into a body lumen of a patient. A distal end of the sheath may include an elevator for changing an orientation of a medical device. A handle may include an actuator. The actuator may be operably connected to the elevator. Activation of the actuator may cause movement of the elevator. An engaging portion may, in at least one configuration of the handle, protrude from a surface of a handle body toward the actuator. A force exerted by the user on at least one of the actuator or the engaging portion may cause the handle to transition between (a) a first configuration in which the engaging portion interacts with the actuator to inhibit movement of the actuator relative to the engaging portion and (b) a second configuration in which the actuator is movable relative to the engaging portion.

Abstract: According to one aspect, a device may include a shaft having a distal end and a lumen, the lumen terminating in a distally-facing opening. An instrument may be inserted through the shaft and may extend through the lumen and out of opening. The device may further include an elevator for engaging the instrument. The elevator may include an actuator extending through at least a portion of the shaft; and a body may be coupled to the actuator. A portion of the body may be configured to extend within the lumen and to apply a force to the instrument and move the instrument into contact with a surface of the lumen when the actuator is moved.

Abstract: A medical system includes a first medical device and a second medical device. The first medical device includes a handle and a shaft. The shaft includes a lumen. A distal portion of the shaft includes an articulation joint, and the lumen extends through at least a portion of the articulation joint. The second medical includes a control device and a rod. The rod is configured to be positioned within at least a portion of the lumen of the shaft within the articulation joint. The control device is configured to control a position of the rod within the shaft. The position of the rod within the shaft controls an articulation angle of the articulation joint.

Abstract: A medical device including an expandable tool configured to extend from a distal end of the medical device. The expandable tool includes a plurality of wires extending from a proximal end of the expandable tool to a distal end of the expandable tool, a plurality of fins extending outwardly from each of the wires of the plurality of wires, and a plurality of projections extending outwardly from each of the fins of the plurality of fins.

Abstract: A medical device may comprise a sheath configured to be inserted into a body lumen of a patient. A distal end of the sheath may include an elevator for changing an orientation of a medical device. A handle may include an actuator. The actuator may be operably connected to the elevator. Activation of the actuator may cause movement of the elevator. An engaging portion may, in at least one configuration of the handle, protrude from a surface of a handle body toward the actuator. A force exerted by the user on at least one of the actuator or the engaging portion may cause the handle to transition between (a) a first configuration in which the engaging portion interacts with the actuator to inhibit movement of the actuator relative to the engaging portion and (b) a second configuration in which the actuator is movable relative to the engaging portion.

Abstract: Medical devices and related methods are described. The medical device may include a shaft, a handle housing a proximal portion of the shaft, and a lock having a first configuration and a second configuration. In the first configuration of the lock, the shaft may be rotatable about a longitudinal axis of the shaft relative to the handle, and, in the second configuration of the lock, the shaft may be stationary relative to the handle.

Abstract: A medical system includes a first medical device and a second medical device. The first medical device includes a handle and a shaft. The shaft includes a lumen. A distal portion of the shaft includes an articulation joint, and the lumen extends through at least a portion of the articulation joint. The second medical includes a control device and a rod. The rod is configured to be positioned within at least a portion of the lumen of the shaft within the articulation joint. The control device is configured to control a position of the rod within the shaft. The position of the rod within the shaft controls an articulation angle of the articulation joint.

Abstract: Various embodiments are generally directed to a flexible elongate member (e.g., endoscopic accessory tool) positionable into and/or through selected anatomies, such as by generating images to position components of a flexible elongate member or to localize anatomic features, for instance. Some embodiments are directed to generating images with a plurality of imaging techniques to localize anatomic features and/or components of a flexible elongate member for one or more of inspection, orientation, and/or facilitating access to body passageways or lumens.

Abstract: A tissue collection system for collecting a sample from the body. The tissue collection system may comprise a tubular member having a proximal end region and a distal end region and defining a lumen extending from the proximal end region to the distal end region, an elongate shaft slidably disposed within the lumen of the tubular member, the elongate shaft extending from a proximal end region to a distal end region, and a tissue collection member disposed adjacent to the distal end region. The tissue collection member may comprise a helically wound coil including a plurality of windings.

Abstract: A tissue collection system for collecting a sample from the body. The system may comprise a tubular member having a proximal end region and a distal end region and defining a lumen extending from the proximal end region to the distal end region, an elongate shaft slidably disposed within the lumen of the tubular member, the elongate shaft extending from a proximal end region to a distal end region, a tissue collection device disposed adjacent to the distal end region of the elongate shaft, and a filter positioned proximal to a distal end region of the tissue collection device when the tissue collection device is in a use configuration.

Abstract: A tissue collection system for collection a sample from the body. The system may include an outer tubular member having a proximal end region and a distal end region and defining a lumen extending from the proximal end region to the distal end region, an inner tubular member slidably disposed within the lumen of the outer tubular member, the inner tubular member defining a lumen extending from a proximal end region to a distal end region of the inner tubular member and an expandable tissue collection device disposed adjacent to the distal end region of the inner tubular member.

Abstract: Medical devices and related methods are described. The medical device may include a shaft, a handle housing a proximal portion of the shaft, and a lock having a first configuration and a second configuration. In the first configuration of the lock, the shaft may be rotatable about a longitudinal axis of the shaft relative to the handle, and, in the second configuration of the lock, the shaft may be stationary relative to the handle.

Abstract: A handle of a medical device may comprise an actuator; a lock movable relative to the actuator and having a feature movable relative to the actuator; and a rack having plurality of teeth separated from one another by a plurality of gaps. The lock may be configured to move the feature from (a) a first configuration, in which the feature is disposed in the gap, between two of the plurality of teeth, such that the two teeth inhibit the actuator from rotating; to (b) a second configuration, in which the feature is disposed outside of the gap, such that the actuator is rotatable. In the second configuration, the teeth may be disposed between the feature and the actuator.

Abstract: Various embodiments are generally directed to a flexible elongate member (e.g., endoscopic accessory tool) positionable into and/or through selected anatomies, such as by generating images to position components of a flexible elongate member or to localize anatomic features, for instance. Some embodiments are directed to generating images with a plurality of imaging techniques to localize anatomic features and/or components of a flexible elongate member for one or more of inspection, orientation, and/or facilitating access to body passageways or lumens.

Abstract: A system may include an expandable member, and a plurality of sensors disposed on an outer surface of the expandable member and circumferentially spaced apart from one another, wherein each of the plurality of sensors includes a first emitter configured to emit light of a first wavelength, and a detector configured to detect light, and a controller coupled to the plurality of sensors.

Abstract: A handle of a medical device may comprise an actuator; a lock movable relative to the actuator and having a feature movable relative to the actuator; and a rack having plurality of teeth separated from one another by a plurality of gaps. The lock may be configured to move the feature from (a) a first configuration, in which the feature is disposed in the gap, between two of the plurality of teeth, such that the two teeth inhibit the actuator from rotating; to (b) a second configuration, in which the feature is disposed outside of the gap, such that the actuator is rotatable. In the second configuration, the teeth may be disposed between the feature and the actuator.

Abstract: A medical device includes a tube comprising a lumen extending from a proximal end to a distal end of the tube, a cap at the distal end of the tube having a distal opening corresponding to the lumen, and an imaging system positioned on a distal-facing surface of the cap. The medical device also includes an instrument at least partially disposed in the lumen that is non-removable from the medical device, an instrument actuation mechanism for controlling the instrument, and a single handle connected to the proximal end of the tube and housing the instrument actuation mechanism. The instrument actuation mechanism, to which a proximal end of the instrument is affixed, may be configured to be moved between a first and second position on the single handle to control an extension and retraction of the instrument relative to the tube.

Abstract: Systems and methods for generating navigational guidance for a medical device within a body are disclosed. One computer-implemented method may include: receiving, at a computer server, image data associated with at least one anatomical object; determining, using a processor associated with the computer server and via application of a trained predictive navigational guidance model to the image data, navigational guidance for the medical device in relation to the at least one anatomical object; generating, based on the determining, at least one visual representation associated with the navigational guidance; and transmitting, to a user device in network communication with the computer server, instructions to display the at least one visual representation associated with the navigational guidance overtop of the image data on a display screen of the user device.

Abstract: A system may include an expandable member, and a plurality of sensors disposed on an outer surface of the expandable member and circumferentially spaced apart from one another, wherein each of the plurality of sensors includes a first emitter configured to emit light of a first wavelength, and a detector configured to detect light, and a controller coupled to the plurality of sensors.

Abstract: A medical device may comprise a sheath configured to be inserted into a body lumen of a patient. A distal end of the sheath may include an elevator for changing an orientation of a medical device. A handle may include an actuator. The actuator may be operably connected to the elevator. Activation of the actuator may cause movement of the elevator. An engaging portion may, in at least one configuration of the handle, protrude from a surface of a handle body toward the actuator. A force exerted by the user on at least one of the actuator or the engaging portion may cause the handle to transition between (a) a first configuration in which the engaging portion interacts with the actuator to inhibit movement of the actuator relative to the engaging portion and (b) a second configuration in which the actuator is movable relative to the engaging portion.