Abstract: A tissue collection system for collection a sample from the body. The system may include an outer tubular member having a proximal end region and a distal end region and defining a lumen extending from the proximal end region to the distal end region, an inner tubular member slidably disposed within the lumen of the outer tubular member, the inner tubular member defining a lumen extending from a proximal end region to a distal end region of the inner tubular member and an expandable tissue collection device disposed adjacent to the distal end region of the inner tubular member.

Abstract: A tissue collection system for collecting a sample from the body. The system may comprise a tubular member having a proximal end region and a distal end region and defining a lumen extending from the proximal end region to the distal end region, an elongate shaft slidably disposed within the lumen of the tubular member, the elongate shaft extending from a proximal end region to a distal end region, a tissue collection device disposed adjacent to the distal end region of the elongate shaft, and a filter positioned proximal to a distal end region of the tissue collection device when the tissue collection device is in a use configuration.

Abstract: A tissue collection system for collecting a sample from the body. The tissue collection system may comprise a tubular member having a proximal end region and a distal end region and defining a lumen extending from the proximal end region to the distal end region, an elongate shaft slidably disposed within the lumen of the tubular member, the elongate shaft extending from a proximal end region to a distal end region, and a tissue collection member disposed adjacent to the distal end region. The tissue collection member may comprise a helically wound coil including a plurality of windings.

Abstract: Medical devices and related methods are described. The medical device may include a shaft, a handle housing a proximal portion of the shaft, and a lock having a first configuration and a second configuration. In the first configuration of the lock, the shaft may be rotatable about a longitudinal axis of the shaft relative to the handle, and, in the second configuration of the lock, the shaft may be stationary relative to the handle.

Abstract: A handle of a medical device may comprise an actuator; a lock movable relative to the actuator and having a feature movable relative to the actuator; and a rack having plurality of teeth separated from one another by a plurality of gaps. The lock may be configured to move the feature from (a) a first configuration, in which the feature is disposed in the gap, between two of the plurality of teeth, such that the two teeth inhibit the actuator from rotating; to (b) a second configuration, in which the feature is disposed outside of the gap, such that the actuator is rotatable. In the second configuration, the teeth may be disposed between the feature and the actuator.

Abstract: Various embodiments are generally directed to a flexible elongate member (e.g., endoscopic accessory tool) positionable into and/or through selected anatomies, such as by generating images to position components of a flexible elongate member or to localize anatomic features, for instance. Some embodiments are directed to generating images with a plurality of imaging techniques to localize anatomic features and/or components of a flexible elongate member for one or more of inspection, orientation, and/or facilitating access to body passageways or lumens.

Abstract: A system may include an expandable member, and a plurality of sensors disposed on an outer surface of the expandable member and circumferentially spaced apart from one another, wherein each of the plurality of sensors includes a first emitter configured to emit light of a first wavelength, and a detector configured to detect light, and a controller coupled to the plurality of sensors.

Abstract: A handle of a medical device may comprise an actuator; a lock movable relative to the actuator and having a feature movable relative to the actuator; and a rack having plurality of teeth separated from one another by a plurality of gaps. The lock may be configured to move the feature from (a) a first configuration, in which the feature is disposed in the gap, between two of the plurality of teeth, such that the two teeth inhibit the actuator from rotating; to (b) a second configuration, in which the feature is disposed outside of the gap, such that the actuator is rotatable. In the second configuration, the teeth may be disposed between the feature and the actuator.

Abstract: A medical device includes a tube comprising a lumen extending from a proximal end to a distal end of the tube, a cap at the distal end of the tube having a distal opening corresponding to the lumen, and an imaging system positioned on a distal-facing surface of the cap. The medical device also includes an instrument at least partially disposed in the lumen that is non-removable from the medical device, an instrument actuation mechanism for controlling the instrument, and a single handle connected to the proximal end of the tube and housing the instrument actuation mechanism. The instrument actuation mechanism, to which a proximal end of the instrument is affixed, may be configured to be moved between a first and second position on the single handle to control an extension and retraction of the instrument relative to the tube.

Abstract: Systems and methods for generating navigational guidance for a medical device within a body are disclosed. One computer-implemented method may include: receiving, at a computer server, image data associated with at least one anatomical object; determining, using a processor associated with the computer server and via application of a trained predictive navigational guidance model to the image data, navigational guidance for the medical device in relation to the at least one anatomical object; generating, based on the determining, at least one visual representation associated with the navigational guidance; and transmitting, to a user device in network communication with the computer server, instructions to display the at least one visual representation associated with the navigational guidance overtop of the image data on a display screen of the user device.

Abstract: A system may include an expandable member, and a plurality of sensors disposed on an outer surface of the expandable member and circumferentially spaced apart from one another, wherein each of the plurality of sensors includes a first emitter configured to emit light of a first wavelength, and a detector configured to detect light, and a controller coupled to the plurality of sensors.

Abstract: According to an example, a handle assembly for a medical device may comprise a handle body, and a first knob for controlling movement of a distal portion of the medical device, the first knob may comprise a first rotational axis, and a second knob for controlling movement of the distal portion of the medical device, the second knob may comprise a second rotational axis, wherein the first rotational axis may be spaced from the second rotational axis.

Abstract: A medical device may comprise a sheath configured to be inserted into a body lumen of a patient. A distal end of the sheath may include an elevator for changing an orientation of a medical device. A handle may include an actuator. The actuator may be operably connected to the elevator. Activation of the actuator may cause movement of the elevator. An engaging portion may, in at least one configuration of the handle, protrude from a surface of a handle body toward the actuator. A force exerted by the user on at least one of the actuator or the engaging portion may cause the handle to transition between (a) a first configuration in which the engaging portion interacts with the actuator to inhibit movement of the actuator relative to the engaging portion and (b) a second configuration in which the actuator is movable relative to the engaging portion.

Abstract: Steerable medical devices display systems including a handle and an elongate shaft extending distally from the handle to a distal tip, a motor control assembly including a motor control housing configured to detachably interface with the handle, a first deflection mechanism disposed within the handle, the first deflection mechanism being configured to deflect the distal tip in a first plane, and a work station in electronic communication with the motor control assembly, the work station including at least a display screen. The work station may be configured to display a dashboard including visual information of a position of the distal tip.

Abstract: A steerable medical device includes a handle and an elongate shaft extending distally from the handle to a distal tip. A motor control assembly including a motor control housing is configured to detachably interface with the handle. The motor control assembly includes a first drive assembly and a second drive assembly disposed within the motor control housing. The motor control assembly includes an input device and a controller that is operably coupled with the first drive assembly, the second drive assembly and the input device. The controller is configured to control operation of the first drive assembly and/or the second drive assembly in order to move the distal tip, receive one or more user inputs from a user via the input device, and to modify operation of the first drive assembly and/or the second drive assembly in accordance with the received one or more inputs.

Abstract: A handle assembly for a medical device including a handle body, and an actuator for controlling an elevator at a distal portion of the medical device, the actuator including a contact portion including a first portion positioned exterior to the handle body and a second portion positioned within an interior portion of the handle body, and an interior body coupled to (i) the contact portion and (ii) a shaft within the handle body, wherein the actuator is configured to move across an exterior surface of the handle body between a first position and a second position, and the actuator is configured to move the elevator to a third position when the user moves the actuator to the first position, and move the elevator to a fourth position when the user moves the actuator to the second position.

Abstract: According to one aspect, a connector assembly for a medical device may comprise a sleeve configured to fixedly couple to a shaft of the medical device and rotatably couple to a handle of the medical device; a collar positioned around the sleeve and configured to couple to the sleeve such that collar (i) may move in a proximal and distal direction relative to sleeve and (ii) may rotate sleeve about a central longitudinal axis when the collar is rotated about the central longitudinal axis; and a biasing member. The connector assembly may be configured to transition between a neutral position and an engaged position.

Abstract: A handle assembly for a medical device is disclosed. The handle assembly may comprise a handle body including a first central longitudinal axis, a first connector portion coupled to a distal end of the handle body, and a shaft extending distally from the first connector portion, wherein a second central longitudinal axis of the shaft is offset from the first central longitudinal axis of the handle body.

Abstract: A medical device may comprise a sheath configured to be inserted into a body lumen of a patient. A distal end of the sheath may include an elevator for changing an orientation of a medical device. A handle may include an actuator. The actuator may be operably connected to the elevator. Activation of the actuator may cause movement of the elevator. An engaging portion may, in at least one configuration of the handle, protrude from a surface of a handle body toward the actuator. A force exerted by the user on at least one of the actuator or the engaging portion may cause the handle to transition between (a) a first configuration in which the engaging portion interacts with the actuator to inhibit movement of the actuator relative to the engaging portion and (b) a second configuration in which the actuator is movable relative to the engaging portion.

Abstract: A medical system includes a first medical device and a second medical device. The first medical device includes a handle and a shaft. The shaft includes a lumen. A distal portion of the shaft includes an articulation joint, and the lumen extends through at least a portion of the articulation joint. The second medical includes a control device and a rod. The rod is configured to be positioned within at least a portion of the lumen of the shaft within the articulation joint. The control device is configured to control a position of the rod within the shaft. The position of the rod within the shaft controls an articulation angle of the articulation joint.