Abstract: A test system is presented for validating and calibrating an active electronically scanned array (AESA) with multiple distinct transceiver elements and associated RF channels. The test system includes a static mount for the AESA, and a test probe fixedly located relative to the static mount. The system also includes a network analyzer connected to the AESA and the test probe, and a test processor connected to the network analyzer. The network analyzer provides RF evaluations of amplitudes and phases/time delays to the test processor, which estimates far field (FF) patterns of the AESA based on these inputs and assessments of free space path losses and propagation delays between the AESA and the test probe. The test processor calculates FF figures of merit (FoMs) for the AESA as a function of frequency, beam scan, and environmentals based on the estimated FF patterns, and validates the AESA based on these FF FoMs.

Abstract: Compounds for use in methods of treating, preventing, or ameliorating pulmonary hypertension; reducing glutamine metabolism in a patient in need thereof, and/or increasing SIRT3 activity in a patient in need thereof.

Abstract: A monopulse active electronically scanned array (AESA) system includes a phased array of RF channels each having an associated emitter element. A method of operating this system includes identifying a desired nulling location, and computationally optimizing theoretical aperture patterns for the AESA system to align geographically coincident nulls of multiple beams of the AESA system with the desired nulling location, the theoretical aperture patterns including nominal values of gain and a time-based parameter (e.g., phase or time delay) for each of the RF channels. Actual values of the gain and time-based parameter for each RF channel corresponding to these nominal values are calibrated by iteratively bisecting gain and time-based parameter tables, respectively, through successively narrower rangers converging on nominal values. The RF channels are then driven according to these calibrated actual time-based parameter and gain values.

Abstract: A method is presented for maximizing equivalent isotropic radiated power (EIRP) of an active electronically scanned array (AESA) system. This AESA system includes a phased array of radio-frequency (RF) channels each having an associated emitter element. A desired nulling location is first identified, constituting a spatial location for transmission nulling relative to the phased array. Theoretical aperture patterns for the AESA system are computed to maximize radiated power while aligning a geographical null of a beam of the AESA system with the desired nulling location. These theoretical aperture patterns include nominal values of gain and a time-based parameter (e.g. phase or time delay) for each RF channel.

Abstract: A method is provided for operating a monopulse active electronically scanned array (AESA) radar system on an aircraft. This system includes multiple emitter elements each with corresponding radio frequency (RF) channels including beamforming integrated circuits (BFICs). The method includes defining multiple modes, with each mode defining an effective aperture by specifying a different plurality of the emitter elements, and determining a preferred state of the AESA system based on a flight phase or environment of the aircraft. One of the plurality of modes is identified as corresponding to the preferred state, and beam steering is calibrated via a beam steering controller (BCM) to produce sum, azimuth difference, and elevation difference beams under the constraint of illuminating all of and only the plurality of the emitter elements corresponding to the selected one of the plurality of modes. BFICs of the emitter elements are then energized according to this calibrated beam steering.

Abstract: An aerial monopulse active electronically scanned array (AESA) radar system includes a phased array of independently controllable radio frequency (RF) channels, a beamforming module, and a transmit/receive module. The beamforming module is configured to cause the phased array to produce a radiation pattern with intercardinal sidelobes oriented along a shortest axis to ground, during flight. The transmit/receive module is configured to half-duplex operation of the phased array by switching between left-hand circular polarization and right-hand circular polarization.

Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating systemic sclerosis, by administration of a therapeutically effective amount of ifetroban or a pharmaceutically acceptable salt thereof.

Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof.

Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed are device implementations for a hybrid energy harvesting device and methods for harvesting mechanical energy from the ambient. The various device implementations utilize a combination of electrostatic energy conversion and piezoelectric energy conversion elements. The method simultaneously converts mechanical energy into electrical charge by electrostatic and piezoelectric energy harvesting. The devices include a piezoelectric harvester including a pair of electrodes and piezoelectric nanocomposite polymer, an electrostatic harvester including an electret film and a pair of electrostatic electrodes.

Abstract: A system for releasing analytes contained within a sample. The system comprises a housing enclosing an interior space. The system additionally comprises a sample holder having at least one receptacle configured to receive a sample containing analytes bound within the sample. The system further includes at least one light emitting diode configured to generate light sufficient to separate photo-cleavable bonds binding the analytes within the sample.

Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating systemic sclerosis, by administration of a therapeutically effective amount of ifetroban or a pharmaceutically acceptable salt thereof.

Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are methods and compositions for high efficiency homologous repair-based gene editing. The methods and compositions of the subject invention can be useful in producing gene-edited livestock and improving human medicine.

Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating systemic sclerosis, by administration of a therapeutically effective amount of ifetroban or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed are device implementations for a hybrid energy harvesting device and methods for harvesting mechanical energy from the ambient. The various device implementations utilize a combination of electrostatic energy conversion and piezoelectric energy conversion elements. The method simultaneously converts mechanical energy into electrical charge by electrostatic and piezoelectric energy harvesting. The devices include a piezoelectric harvester including a pair of electrodes and piezoelectric nanocomposite polymer, an electrostatic harvester including an electret film and a pair of electrostatic electrodes.

Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof.

Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof.

Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating systemic sclerosis, by administration of a therapeutically effective amount of ifetroban or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are material and methods for changing gene expression in select sex chromosomes. The materials and methods of the subject invention can be used to produce non-human transgenic animals that produce progeny of a predetermined gender and to generate non-human transgenic animals that produce single-sexed semen.