Abstract: A progress tracking system 100 for displaying progress of at least one student by way of a graphical user interface (GUI) is disclosed. The system 100 comprises a server 130 and at least one user device 110. The server 130 is configured to store information comprising at least an identity of the student, at least one goal of the student and progress data of the student towards achieving the goal. The user device 110 is configured to launch a progress tracking application that tracks the progress of the student towards the achievement the goal based on the progress data of that student. The progress tracking application generates and displays at least one indicator providing a visual indication of the progress of the student.

Abstract: A semiconductor device includes a metal base, a wall, a lid, a semiconductor die, and at least one capacitor. The wall is placed on the metal base, and provides an opening portion inside of the wall. The lid is placed on the wall. The semiconductor die is placed on the metal base. The semiconductor die is surrounded with the wall to be placed in the opening portion. The capacitor is placed on the wall. A first end of the capacitor is electrically connected to the semiconductor die, and a second end of the capacitor is electrically connected to the metal base.

Abstract: Implementations describe systems and methods for manufacturing and performing quality assessment of dental appliances. In one embodiment, a method of manufacturing a dental appliance comprises receiving, at a holder, a feature of the dental appliance, the feature comprising a first surface having a first shape, wherein the holder holds the feature of the dental appliance at a reference position. The method further includes automatically placing an object against the feature at the reference position using a robot arm, wherein the object comprises a second surface having a second shape that mates with the first shape. The method further includes applying pressure to press the object against the feature of the dental appliance and bonding the object to the feature of the dental appliance while applying the pressure.

Abstract: Described in various embodiments herein are tiled amplification nucleic acid detection systems and uses thereof. In some embodiments, the nucleic acids amplified and detected are cell free DNA (cfDNA).

Abstract: A pressure regulating or pressure relief device comprises an inlet and an outlet chamber with an outlet. The inlet is in fluid communication with the outlet chamber. A valve seat is located between the inlet and the outlet. A valve member is biased to seal against the valve seat, and displaces from the valve seat by an inlet pressure at the inlet increasing above a pressure threshold to allow a flow of gases from the inlet to the outlet via the outlet chamber. The flow of gases through the outlet causes an outlet pressure in the outlet chamber to act on the valve member together with the inlet pressure to displace the valve member from the valve seat.

Abstract: The present disclosure relates to methods and intermediates useful for preparing a compound of formula I: or a co-crystal, solvate, salt or combination thereof.

Abstract: A semiconductor device according to the present disclosure includes a source electrode provided on a substrate, a gate electrode provided-on the substrate and surrounding a part of the source electrode, a drain electrode provided on the substrate and surrounding the gate electrode, and a gate wiring provided on the substrate, wherein a first end of the gate wiring is connected to only one portion of the gate electrode and a second end of the gate wiring is connected to a first gate bus bar.

Abstract: The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents such as siRNAs, able to Inhibin Subunit Beta E (INHBE) gene expression. Also disclosed are pharmaceutical compositions that include INHBE RNAi agents and methods of use thereof. The INHBE RNAi agents disclosed herein may be conjugated to targeting ligands to facilitate the delivery to cells, including to hepatocytes. Delivery of the INHBE RNAi agents in vivo provides for inhibition of INHBE gene expression. The RNAi agents can be used in methods of treatment of diseases, disorders, or symptoms mediated in part by INHBE gene expression, such as obesity, diabetes, liver inflammation, dyslipidemia, or metabolic disease.

Abstract: This invention allows an end user (“client”) to access one of any number of devices via a server (or cluster of server instances). Each device may be in a different physical location and different location on the Internet or other network. Each device might also be behind a router or firewall that makes direct access to the device impossible. Clients may optionally be authenticated to ensure they are authorized to access a particular device, and devices may also be authenticated to verify their identity to prevent spoofing. Access to a device is achieved by tunneling network requests over a persistent connection that the device establishes when it first comes online.

Abstract: Disclosed herein are methods and systems utilizing CRISPR effector systems for assays and diagnostics. Embodiments herein provide tile probes in systems and methods for detection of multiple targets across a given genome or group of genomes, including in circulating nucleic acid samples.

Abstract: Methods and apparatus for a lift pin mechanism for substrate processing chambers are provided herein. In some embodiments, the lift pin mechanism includes a lift pin comprising a shaft with a top end, a bottom end, and a coupling end at the bottom end; a bellows assembly disposed about the shaft. The bellows assembly includes an upper bellows flange having an opening for axial movement of the shaft; a bellows having a first end coupled to a lower surface of the upper bellows flange such that the shaft extends into a central volume surrounded by the bellows; and a bellows guide assembly coupled to a second end of the bellows to seal the central volume. The shaft is coupled to the bellows guide assembly at the coupling end. The bellows guide assembly is axially movable to move the lift pin with respect to the upper bellows flange.

Abstract: A treatment delivery system includes a fluid delivery system connected to a first fluid reservoir and a second fluid reservoir. The system directs a first fluid from the first fluid reservoir to a treatment site and directs a second fluid from the second fluid reservoir to the treatment site and a control unit to control the fluid delivery system according to a treatment process comprising a flow of the first fluid and the second fluid, the treatment process including multiple phases. A first phase includes a controlled delivery of the first fluid from the first fluid reservoir to the treatment site. A second phase of the plurality of phases includes a controlled delivery of the second fluid from the second fluid reservoir to the treatment site, the control unit automatically activating a transition from at least the first phase to the second phase.

Abstract: Methods, compositions, and kits are provided for the detection of Influenza A in a test sample. The presence or absence of Influenza A in the sample is determined by nucleic acid based assays using primers and/or probes with excellent sensitivity, specificity and inclusivity for detecting Influenza A strains and/or subtypes Detection strategies may utilize loop mediated isothermal amplification (LAMP) and molecular beacon hybridization.

Abstract: A micro-light emitting diode (uLED) device comprises: a mesa comprising: a plurality of semiconductor layers including an n-type layer, an active layer, and a p-type layer; a p-contact layer contacting the p-type layer; a cathode contacting the first sidewall of the n-type layer; a first region of dielectric material that insulates the p-contact layer, the active layer, and a first sidewall of the p-type layer from the cathode; an anode contacting the top surface of the p-contact layer; and a second region of dielectric material that insulates the active layer, a second sidewall of the p-type layer, and the second sidewall of the n-type layer from the anode. The top surface of the p-contact layer has a different planar orientation compared to the first and second sidewalls of the n-type layer. Methods of making and using the uLED devices are also provided.

Abstract: A Doherty amplifier includes a substrate, a first transistor provided on the substrate and including first gate electrodes, first drain electrodes, a first gate bus bar and a first drain bus bar, a second transistor provided on the substrate and including second gate electrodes, second drain electrodes, a second gate bus bar having a first end, and a second drain bus bar, a combining node provided on the substrate and combining a first signal amplified by the first transistor and a second signal amplified by the second transistor, a first line provided on the substrate and connecting the first drain bus bar and the combining node, and a second line provided on the substrate, connecting the second drain bus bar and the combining node, and connected to a second end of the second drain bus bar located diagonally across the second transistor with respect to the first end.

Abstract: A micro-light emitting diode (uLED) device comprises: a mesa comprising: a plurality of semiconductor layers including an n-type layer, an active layer, and a p-type layer; a p-contact layer contacting the p-type layer; a cathode contacting the first sidewall of the n-type layer; a first region of dielectric material that insulates the p-contact layer, the active layer, and a first sidewall of the p-type layer from the cathode; an anode contacting the top surface of the p-contact layer; and a second region of dielectric material that insulates the active layer, a second sidewall of the p-type layer, and the second sidewall of the n-type layer from the anode. The top surface of the p-contact layer has a different planar orientation compared to the first and second sidewalls of the n-type layer. Methods of making and using the uLED devices are also provided.

Abstract: An interactive graphic design system design interface is described to enable design users to create a variant component that links multiple design elements as variants, where each variant represents a state or version of a run-time object, feature or user-interface.

Abstract: A micro-light emitting diode (uLED) device comprises: a mesa comprising: a plurality of semiconductor layers including an n-type layer, an active layer, and a p-type layer; a p-contact layer contacting the p-type layer; a cathode contacting the first sidewall of the n-type layer; a first region of dielectric material that insulates the p-contact layer, the active layer, and a first sidewall of the p-type layer from the cathode; an anode contacting the top surface of the p-contact layer; and a second region of dielectric material that insulates the active layer, a second sidewall of the p-type layer, and the second sidewall of the n-type layer from the anode. The top surface of the p-contact layer has a different planar orientation compared to the first and second sidewalls of the n-type layer. Methods of making and using the uLED devices are also provided.

Abstract: A semiconductor device includes a source bus bar provided on a first surface of a substrate and overlapping with a first via hole penetrating through the substrate, a plurality of first transistors arranged in a second direction intersecting a first direction, each of the first transistors including a first source finger, a first drain finger and a first gate finger which extend in the first direction on the first surface, the first source finger being electrically connected to the source bus bar, and a plurality of second transistors arranged in the second direction, each of the second transistors including a second source finger, a second drain finger and a second gate finger which extend in the first direction on the first surface, the second source finger being electrically connected to the source bus bar, the first transistors and the second transistors sandwiching the source bus bar.