Patents by Inventor James Zhou

James Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260092309
    Abstract: The present disclosure provides compositions with ultra sensitivity for detecting a biomarker and the method of use thereof. In one embodiment, the composition comprises (1) a capture probe capable of binding to a biomarker and comprising a nucleic acid having a tail polynucleotide sequence; (2) a poly-oligonucleotide conjugate comprising a carrier conjugated with a plurality of oligonucleotides, wherein each oligonucleotide comprises a first region comprising multiple repeating polynucleotide sequences, wherein at least one of the plurality of oligonucleotides comprises a second region capable of directly or indirectly associating with the tail polynucleotide sequence; and (3) a plurality of label probes, wherein each label probe capable of directly or indirectly associating with the repeating polynucleotide sequence, wherein the capture probe, the poly-oligonucleotide conjugate and the plurality of label probes form a complex.
    Type: Application
    Filed: June 12, 2025
    Publication date: April 2, 2026
    Inventors: Chang Liu, Rajan Giri, Guixi Li, James Zhou, Yijun Su
  • Patent number: 12589107
    Abstract: The present invention belongs to the medical and technical field and provides a medicine or health food composition of nicotinamide mononucleotide and mogroside. In addition, the present invention also provides the preparation method, formulation and application of the composition.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: March 31, 2026
    Assignees: Beijing Hebabiz Biotechnology Co., Inc., Beijing Hebabiz Management Co., Ltd.
    Inventors: James Zhou, Bai-Bo Xie, Xinyu Zang
  • Publication number: 20250302795
    Abstract: The invention pertains to the field of medical technology and health food, in particular, specifically providing a small molecule composition that exerts negative regulation on the Nrf2 signaling pathway. This composition comprises licorice chalcone A, licorice chalcone C, licorice chalcone D, licorice chalcone E, formononetin, glabrone and Licoflavone C, which can be utilized for the prevention or treatment of non-alcoholic fatty liver disease.
    Type: Application
    Filed: January 4, 2023
    Publication date: October 2, 2025
    Applicant: Beijing Hebabiz Biotechnology Co., Inc.
    Inventors: James Zhou, Bai-Bo Xie
  • Patent number: 11957726
    Abstract: A pharmaceutical composition or a health food composition for controlling blood sugar, raw materials of which include dioscoreae rhizome, medlar, and coconut oil. A preparation method for the composition includes: mixing dioscoreae rhizome and a decoction thereof with medlar for homogenization, pulverization and drying, and mixing the resultant product with coconut oil and water, followed by baking and drying. Further disclosed are a pharmaceutical preparation or a health food including the composition and an excipient, and a use of the composition in the preparation of a pharmaceutical preparation or a health food for reducing or eliminating diabetic conditions.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: April 16, 2024
    Assignee: BEIJING HEBABIZ BIOTECHNOLOGY CO., INC.
    Inventor: James Zhou
  • Patent number: 11731959
    Abstract: This invention provides synthesis method, crystallization method, etc. for troxacitabine, and also the crystal form and use of troxacitabine.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: August 22, 2023
    Assignees: BEIJING HEBABIZ BIOTECHNOLOGY CO., INC., GUANGXI HEBABIZ PHARMACEUTICAL TECHNOLOGY CO., LTD.
    Inventor: James Zhou
  • Publication number: 20220133763
    Abstract: The present invention belongs to the medical and technical field and provides a medicine or health food composition of nicotinamide mononucleotide and mogroside. In addition, the present invention also provides the preparation method, formulation and application of the composition.
    Type: Application
    Filed: March 14, 2019
    Publication date: May 5, 2022
    Applicants: Beijing Hebabiz Biotechnology Co., Inc., Beijing Hebabiz Management Co., Ltd.
    Inventors: James Zhou, Bai-Bo Xie, Xinyu Zang
  • Patent number: 11301969
    Abstract: Some implementations provide improved user experiences on head mounted devices (HMDs) that provide near eye viewing, e.g., HMDs that display distorted images and provide lenses that undistort the images for the user. The images are produced using distortion that is corrected dynamically based on context to conserve device resources. To do so, a context associated with a state of the user, the HMD, or content being viewed on the HMD is tracked during the user experience. For example, the device may predict pupil position, eye state, eye gaze direction, or eye fixation, content type, connection mode, and other context. The device uses the tracked context to determine how to correct distortion for the images at different points during the user experience. For example, new distortion corrections may be computed and used while the user's gaze is moving and previously-determined distortion corrections may be used while the user's gaze is fixed.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: April 12, 2022
    Assignee: Apple Inc.
    Inventors: Moinul Khan, Simon Fortin-Deschenes, Yanli Zhang, Bennett S. Wilburn, Sterling G. Orsten, Nan Zhu, James Zhou
  • Patent number: 11160842
    Abstract: A traditional Chinese medicine composition for protecting the liver and kidney and a preparation method and use thereof. The composition is composed of 100-200 parts of Polygonatum odoratum, 100-200 parts of fructus lycii, 80-160 parts of radix ophiopogonis, 70-130 parts of Angelica sinensis, 70-130 parts of semen cassiae, 70-130 parts of white peony root, 70-130 parts of dried orange peel, 70-130 parts of prepared rehmannia root, 70-130 parts of chrysanthemum, 30-70 parts of rhizome chuanxiong, 20-40 parts of Irkutsk anemone rhizome, and 10-20 parts of bupleurum by weight.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: November 2, 2021
    Assignee: GUANGXI HEBABIZ PHARMACEUTICAL TECHNOLOGY CO., LTD
    Inventor: James Zhou
  • Patent number: 10894070
    Abstract: A pharmaceutical composition includes an alcohol-soluble, water insoluble, extract of Radix Glycyrrhizae; and wolfberry. A weight ration of the extract and wolfberry is 0.01˜5:15˜25. The composition is useful for controlling blood glucose and blood lipids, and for weight control. Health food products containing the recited combination are also provided.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: January 19, 2021
    Inventors: James Zhou, Dong Chen
  • Publication number: 20200276258
    Abstract: A pharmaceutical composition or a health food composition for controlling blood sugar, raw materials of which include Dioscoreae rhizome, medlar, and coconut oil. A preparation method for the composition includes: mixing Dioscoreae rhizome and a decoction thereof with medlar for homogenization, pulverization and drying, and mixing the resultant product with coconut oil and water, followed by baking and drying. Further disclosed are a pharmaceutical preparation or a health food including the composition and an excipient, and a use of the composition in the preparation of a pharmaceutical preparation or a health food for reducing or eliminating diabetic conditions.
    Type: Application
    Filed: September 8, 2017
    Publication date: September 3, 2020
    Applicant: BEIJING HEBABIZ BIOTECHNOLOGY CO., Inc.
    Inventor: James Zhou
  • Publication number: 20200247787
    Abstract: This invention provides synthesis method, crystallization method, etc. for troxacitabine, and also the crystal form and use of troxacitabine.
    Type: Application
    Filed: April 18, 2016
    Publication date: August 6, 2020
    Applicants: BEIJING HEBABIZ BIOTECHNOLOGY CO., LTD., GUANGXI HEBABIZ PHARMACEUTICAL TECHNOLOGY CO.,LTD.
    Inventor: James Zhou
  • Patent number: 10548940
    Abstract: The invention provides a traditional Chinese medicine composition for the control of blood lipids and/or weight of body, which includes Poria and Paeoniae Radix Alba, etc. the traditional Chinese medicine composition can be applied in reducing the total cholesterol level, triacylglycerol level, and low density lipoprotein cholesterol level in the body; increasing body high density lipoprotein cholesterol level, reducing uric acid level, and/or reducing symptoms of fatty liver. The invention also provides preparation methods and applications of this traditional Chinese medicine composition.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: February 4, 2020
    Assignee: BEIJING HEBABIZ BIOTECHNOLOGY CO., Inc.
    Inventor: James Zhou
  • Publication number: 20190336882
    Abstract: The present disclosure provides processes and systems for ethanol production. In one embodiment, a first beer column receives a first portion of a feed mixture including ethanol and water to form a first beer column bottom stream and a first beer column vaporous overhead stream. A beer column receives a second portion of the feed mixture. A first portion of the first beer column bottom stream is forwarded to a first beer column reboiler. A second portion of the first beer column bottom stream is forwarded to a plurality of evaporators. A condensed portion of the first beer column vaporous overhead stream is forwarded to a stripper column. The stripper column forms a feed stream, which is contacted with a separation system, thereby forming a permeate and a retentate. The permeate is forwarded directly to at least one selected from the first beer column and the stripper column.
    Type: Application
    Filed: May 7, 2019
    Publication date: November 7, 2019
    Inventors: Virginia Andrade, James Zhou, Stephan Rudiger Blum
  • Publication number: 20190167752
    Abstract: A traditional Chinese medicine composition for protecting the liver and kidney and a preparation method and use thereof. The composition is composed of 100-200 parts of Polygonatum odoratum, 100-200 parts of fructus lycii, 80-160 parts of radix ophiopogonis, 70-130 parts of Angelica sinensis, 70-130 parts of semen cassiae, 70-130 parts of white peony root, 70-130 parts of dried orange peel, 70-130 parts of prepared rehmannia root, 70-130 parts of chrysanthemum, 30-70 parts of rhizome chuanxiong, 20-40 parts of Irkutsk anemone rhizome, and 10-20 parts of bupleurum by weight.
    Type: Application
    Filed: April 29, 2015
    Publication date: June 6, 2019
    Inventor: James Zhou
  • Patent number: 9943560
    Abstract: The invention provides drug compositions with synergistic effects, which includes alcohol-soluble and water-insoluble liquorices extracts and at least one kind of anti-tumor or glucose-and-lipid-lowering drug/eatable substance, and can be used to treat tumor or lower blood glucose and lipid. Besides, the invention also provides pharmaceutical preparation, pharmaceutical application, therapeutic and preparation methods, etc. related to this drug compositon.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: April 17, 2018
    Inventors: James Zhou, Dong Chen
  • Patent number: 9736456
    Abstract: A method of converting two-dimensional image data to three-dimensional image data includes dividing the image data into blocks, performing motion estimation on the blocks to produce block-based motion vectors, applying a global motion analysis and a local motion analysis to the block-based motion vectors to generate motion-based depth, applying a global image model and a local image model to the block-based motion vectors to generate image-based depth, and generating a three-dimensional view by fusing the motion-based depth and the image-based depth. Other conversion methods are also included.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: August 15, 2017
    Assignee: PIXELWORKS, INC.
    Inventors: Tao Chen, Bob Zhang, Junhua Chen, Ji Zhao, Neil D. Woodall, James Zhou
  • Patent number: 9648347
    Abstract: A method of generating new views for a multi-view display system includes receiving a block-based disparity estimate between left image data and right image data for a frame of image data at a processor, upscaling the block-based disparity estimate to a pixel-based disparity for each pixel in the image date, performing motion vector based disparity interpolation and image interpolation simultaneously to produce left and right side interpolated data, and generating at least one new view using left and right side interpolated data.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: May 9, 2017
    Assignee: PIXELWORKS, INC.
    Inventors: Guohua Cheng, Neil D. Woodall, James Zhou, Yue Ma
  • Publication number: 20170080043
    Abstract: The invention provides a traditional Chinese medicine composition for the control of blood lipids and/or weight of body, which includes Poria and Paeoniae Radix Alba, etc. the traditional Chinese medicine composition can be applied in reducing the total cholesterol level, triacylglycerol level, and low density lipoprotein cholesterol level in the body; increasing body high density lipoprotein cholesterol level, reducing uric acid level, and/or reducing symptoms of fatty liver. The invention also provides preparation methods and applications of this traditional Chinese medicine composition.
    Type: Application
    Filed: November 4, 2014
    Publication date: March 23, 2017
    Inventor: James Zhou
  • Patent number: 9524008
    Abstract: An apparatus includes a display device having a pixel and vector storage, and a by-pass mode and an interpolation mode, wherein the interpolation mode converts input data from an input frame rate to a display refresh rate based on pixel and vector data stored in the storage. A method includes determining a selected interpolation mode to be employed by a frame interpolator, retrieving pixel data and vector data received from a host system from a storage, and generating interpolated frames of display data according to the selected interpolation mode.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: December 20, 2016
    Assignee: PIXELWORKS, INC.
    Inventors: Neil D. Woodall, James Zhou, Bob Zhang, Richard Miller
  • Publication number: 20140127334
    Abstract: This invention provides compound health food compound containing licorice extract, which is made by alcohol-soluble and water-insoluble Radix Glycyrrhizae extracts and wolfberry. The compound can be used for the prevention and/or treatment of high blood sugar, high cholesterol and/or obesity. Besides, this invention also provides pharmaceutical preparation, pharmaceutical application, therapeutic preparation methods, etc. related to this drug compound.
    Type: Application
    Filed: March 26, 2012
    Publication date: May 8, 2014
    Inventors: James Zhou, Dong Chen