Abstract: A sanitary cover for a telephone mouthpiece or earpiece has a central portion and side portions. The side portions have a retaining member formed thereon for engaging in a groove of a standard telephone mouthpiece. The retaining members allow the sanitary cover to be mounted and held securely on a telephone mouthpiece during use and are easily removed from the telephone mouthpiece when the cover is no longer needed. A method of forming a sanitary cover for a telephone mouthpiece involves cutting at least a first and second sheet of flexible material to have first and second physical dimensions, respectively. The first and second sheets are molded to the shape of a standard telephone mouthpiece and are mechanically bonded together. The difference in physical dimensions between the first and second sheets forming the cover allow the cover to retain its shape even though the covers are folded and stacked for storage and packaging.