Abstract: A method for using a defoaming formulation useful as an antifoaming agent, a foam controlling agent, or a defoaming agent. The method comprises adding the defoaming formulation that comprises one or more alkoxylate species to a system, wherein the one or more alkoxylate species is characterized as Acc-[(Ox)i]n, wherein Acc is an acceptor having a functionality of n ranging between 1 and about 100. (Ox)i are oxide blocks, each oxide block having a composition comprising from 1 to 150,000 units of oxide species selected from ethylene oxide, propylene oxide, butylene oxide or combinations thereof and i ranges between 1 and about 10. The composition of adjacent oxide blocks is different and the average molecular weight of the one or more alkoxylate species is greater than about 2500 gmole?1. Some embodiments of the present inventions have mixtures of alkoxylate species having average molecular weights between about 5000 and about 3,000,000 gmole?1.