Patents by Inventor Jamie O'Brien

Jamie O'Brien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240092882
    Abstract: The present invention provides methods for treating an allergy by administering one or more antibodies that bind specifically to the allergen. In certain embodiments, the antibodies useful for treating an allergen, bind specifically to the cat allergen, Fel d1. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to Fel d1. The antibodies of the invention are useful for binding to the Fel d1 allergen in vivo, thus preventing binding of the Fel d1 allergen to pre-formed IgE on the surface of mast cells or basophils. In doing so, the antibodies act to prevent the release of histamine and other inflammatory mediators from mast cells and/or basophils, thus ameliorating the untoward response to the cat allergen in sensitized individuals.
    Type: Application
    Filed: September 6, 2023
    Publication date: March 21, 2024
    Inventors: Meagan O'BRIEN, Gary HERMAN, Allen RADIN, Michelle DEVEAUX, Lorah PERLEE, Jamie M. ORENGO
  • Publication number: 20240037345
    Abstract: Systems, methods, and computer-readable storage media for receiving data at a computer system, wherein the data has a plurality of rows; receiving, from a user at the computer system, a description of a task associated with the data; receiving, from the user at the computer system, a plurality of example transformations; combining, via at least one processor of the computer system, the task description together with the plurality of example transformations and input and output labels, resulting in a prompt; executing, via the at least one processor, a machine learning model, wherein the prompt is an input to the machine learning model, and wherein output of the machine learning model comprises an algorithm for executing the task; and executing, via the at least one processor, the task on the data using the algorithm.
    Type: Application
    Filed: July 28, 2022
    Publication date: February 1, 2024
    Applicant: Yext, Inc.
    Inventors: Jamie O'Brien, Maxwell Shaw, Michael Misiewicz, Pierce Stegman, Andrew Lauria, Vinay Ramkrishnan, Amichai Z. Berman, Steven Sanshwe, Diana Keung, Jesse Sharps, Jesse Shatsky, Rachel Adler
  • Publication number: 20240028585
    Abstract: Implementations of the disclosure provide a system for managing data suggestions processed by multiple different source systems. A first suggestion associated with first data associated with an entity system is received from a first system. A second suggestion associated with the first data associated with the entity system is received from a second system. An indication of an acceptance of the first suggestion is received from the entity system. The first suggestion is applied to the first data to generate updated first data. The updated first data is transmitted to the first system and the second system.
    Type: Application
    Filed: October 3, 2023
    Publication date: January 25, 2024
    Inventors: Steven Sanshwe, Rajeev Rajagopalan Krithivasan, Jamie O'Brien, Jesse Shatsky, Bryan Reed, Catherine Frailey, Sanket Alekar
  • Patent number: 11809411
    Abstract: Implementations of the disclosure provide a system for managing data suggestions processed by multiple different source systems. The system includes a memory to store data associated with one or more entities; and a processing device coupled to the memory to identify a first indication associated with a first source system, the first indication corresponding to a first data suggestion associated with a first portion of entity data associated with an entity system. A second indication associated with a second source system is identified, the second indication corresponding to a second data suggestion associated with the first portion of the entity data. An interface including an integrated set of data suggestions is generated, the integrated set of data suggestions includes the first data suggestion and the second data suggestion. The interface is configured to receive input data from the entity system, wherein the input data indicates an acceptance of the first data suggestion.
    Type: Grant
    Filed: March 19, 2021
    Date of Patent: November 7, 2023
    Assignee: Yext, Inc.
    Inventors: Steven Sanshwe, Rajeev Rajagopalan Krithivasan, Jamie O'Brien, Jesse Shatsky, Bryan Reed, Catherine Frailey, Sanket Alekar
  • Publication number: 20210294792
    Abstract: Implementations of the disclosure provide a system for managing data suggestions processed by multiple different source systems. The system includes a memory to store data associated with one or more entities; and a processing device coupled to the memory to identify a first indication associated with a first source system, the first indication corresponding to a first data suggestion associated with a first portion of entity data associated with an entity system. A second indication associated with a second source system is identified, the second indication corresponding to a second data suggestion associated with the first portion of the entity data. An interface including an integrated set of data suggestions is generated, the integrated set of data suggestions includes the first data suggestion and the second data suggestion. The interface is configured to receive input data from the entity system, wherein the input data indicates an acceptance of the first data suggestion.
    Type: Application
    Filed: March 19, 2021
    Publication date: September 23, 2021
    Inventors: Steven Sanshwe, Rajeev Rajagopalan Krithivasan, Jamie O'Brien, Jesse Shatsky, Bryan Reed, Catherine Frailey, Sanket Alekar
  • Publication number: 20200311673
    Abstract: The systems and methods provided herein are directed to a delivery system for orders from a variety of businesses located along a transport route of an aerial vehicle. Fresh food, geographically unique goods, customized goods, and other retail items are ordered by passengers while in transit over ground-based locations. Scheduled in-flight deliveries provide the ordered goods to the passengers.
    Type: Application
    Filed: March 29, 2019
    Publication date: October 1, 2020
    Inventors: Michael T. SAILER, Annika E. Nordlund-Swenson, Nathan G. Brown, Jamie O'Brien
  • Patent number: 9012439
    Abstract: The present invention is directed to a method of inducing platelet production that includes contacting a megakaryocyte with an electrophilic compound under conditions effective to induce platelet production by the contacting megakaryocyte. Methods of treating a patient for low platelet levels, increasing the circulating half-life of platelets, and improving the quality (activity) of platelets are also disclosed herein, which involve administering the electrophilic compound to a patient an effective amount to achieve the desired effect. Pharmaceutical compositions and therapeutic systems are also disclosed for carrying out these therapeutic treatments.
    Type: Grant
    Filed: October 29, 2008
    Date of Patent: April 21, 2015
    Assignee: University of Rochester
    Inventors: Richard P. Phipps, Jamie O'Brien
  • Publication number: 20110027223
    Abstract: The present invention is directed to a method of inducing platelet production that includes contacting a megakaryocyte with an electrophilic compound under conditions effective to induce platelet production by the contacting megakaryocyte. Methods of treating a patient for low platelet levels, increasing the circulating half-life of platelets, and improving the quality (activity) of platelets are also disclosed herein, which involve administering the electrophilic compound to a patient an effective amount to achieve the desired effect. Pharmaceutical compositions and therapeutic systems are also disclosed for carrying out these therapeutic treatments.
    Type: Application
    Filed: October 29, 2008
    Publication date: February 3, 2011
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Richard P. Phipps, Jamie O'Brien