Patents by Inventor Jamie Raudensky Doyle

Jamie Raudensky Doyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bovine adrenal medulla peptide 8-22 compounds and methods of use thereof for treating pain
    Patent number: 11718646
    Abstract: The present disclosure relates to, among other things, compounds and methods for treating neuropathic pain, ocular pain, ocular inflammation, and/or dry eye and methods of detecting mutations in specific G-protein coupled receptors, such as missense mutations, and determining the extent to which these mutations alter the pharmacological response of the G-protein coupled receptor.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: August 8, 2023
    Assignees: Tufts Medical Center, Trustees of Tufts College
    Inventors: Alan S. Kopin, Krishna Kumar, Jamie Raudensky Doyle
  • METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS
    Publication number: 20220135633
    Abstract: The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest.
    Type: Application
    Filed: November 12, 2021
    Publication date: May 5, 2022
    Inventors: Charles COHEN, Krishna KUMAR, Jamie Raudensky DOYLE, Alan S. KOPIN
  • Methods and systems for designing and/or characterizing soluble lipidated ligand agents
    Patent number: 11254720
    Abstract: The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: February 22, 2022
    Assignees: On Target Therapeutics LLC, Trustees of Tufts College, Tufts Medical Center
    Inventors: Charles Cohen, Krishna Kumar, Jamie Raudensky Doyle, Alan S. Kopin
  • COMPOUNDS AND METHODS FOR TREATING PAIN
    Publication number: 20210101934
    Abstract: The present disclosure relates to, among other things, compounds and methods for treating neuropathic pain, ocular pain, ocular inflammation, and/or dry eye and methods of detecting mutations in specific G-protein coupled receptors, such as missense mutations, and determining the extent to which these mutations alter the pharmacological response of the G-protein coupled receptor.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Inventors: Alan S. KOPIN, Krishna KUMAR, Jamie Raudensky DOYLE
  • Compounds and methods for treating pain
    Patent number: 10899796
    Abstract: The present disclosure relates to, among other things, compounds and methods for treating neuropathic pain, ocular pain, ocular inflammation, and/or dry eye and methods of detecting mutations in specific G-protein coupled receptors, such as missense mutations, and determining the extent to which these mutations alter the pharmacological response of the G-protein coupled receptor.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: January 26, 2021
    Assignees: Tufts Medical Center, Trustees of Tufts College
    Inventors: Alan S. Kopin, Krishna Kumar, Jamie Raudensky Doyle
  • Methods and Systems for Designing and/or Characterizing Soluble Lipidated Ligand Agents
    Publication number: 20190135882
    Abstract: The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest.
    Type: Application
    Filed: January 11, 2019
    Publication date: May 9, 2019
    Inventors: Charles Cohen, Krishna Kumar, Jamie Raudensky Doyle, Alan S. Kopin
  • Methods and systems for designing and/or characterizing soluble lipidated ligand agents
    Patent number: 10233219
    Abstract: The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: March 19, 2019
    Assignees: Tufts Medical Center, Trustees of Tufts College, On Target Therapeutics LLC
    Inventors: Charles Cohen, Krishna Kumar, Jamie Raudensky Doyle, Alan S. Kopin
  • COMPOUNDS AND METHODS FOR TREATING PAIN
    Publication number: 20180319842
    Abstract: The present disclosure relates to, among other things, compounds and methods for treating neuropathic pain, ocular pain, ocular inflammation, and/or dry eye and methods of detecting mutations in specific G-protein coupled receptors, such as missense mutations, and determining the extent to which these mutations alter the pharmacological response of the G-protein coupled receptor.
    Type: Application
    Filed: November 9, 2016
    Publication date: November 8, 2018
    Inventors: Alan S. Kopin, Krishna Kumar, Jamie Raudensky Doyle
  • METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS
    Publication number: 20160052982
    Abstract: The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 25, 2016
    Inventors: Charles Cohen, Krishna Kumar, Jamie Raudensky Doyle, Alan S. Kopin