Patents by Inventor Jamie Simpson
Jamie Simpson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11975073Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: June 26, 2023Date of Patent: May 7, 2024Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Rishab R. Shyam, Jamie Simpson, Christopher John Porter, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Patent number: 11969553Abstract: A first part of a fluid connector system for delivery of pressurized breathing gas to a patient from a respiratory pressure therapy device. The first part has a connector portion with a first opening for a fluid flow, a sealing surface around a periphery of the first opening, and a retaining portion axially aligned with the sealing surface. The sealing surface is configured to axially receive a seal portion extending around a periphery of a second opening to form a face seal with a second part of the fluid connector system. The retaining portion is configured to be releasably engaged with a retaining portion of the second part of the fluid connector system.Type: GrantFiled: October 28, 2020Date of Patent: April 30, 2024Assignee: ResMed Pty LtdInventors: James McKensey Bencke, Justin John Formica, Richard Llewelyn Jones, Joseph Samuel Ormrod, Mark Simpson, Jamie Graeme Wehbeh
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Patent number: 11938137Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: January 27, 2022Date of Patent: March 26, 2024Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
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Publication number: 20240050573Abstract: The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that promote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.Type: ApplicationFiled: June 28, 2023Publication date: February 15, 2024Applicant: Monash UniversityInventors: Christopher John Porter, Jamie Simpson, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Patent number: 11883497Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: August 29, 2018Date of Patent: January 30, 2024Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, James T. Mutamba, Rishab R. Shyam, Jamie Simpson, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Natalie Trevaskis
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Publication number: 20230338552Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: June 26, 2023Publication date: October 26, 2023Applicants: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Rishab R. Shyam, Jamie Simpson, Christopher John Porter, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Patent number: 11738087Abstract: The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that pro mote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.Type: GrantFiled: September 8, 2016Date of Patent: August 29, 2023Assignee: Monash UniversityInventors: Chris Porter, Jamie Simpson, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Patent number: 11608345Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: December 19, 2018Date of Patent: March 21, 2023Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Sifei Han, Luojuan Hu, Ketki Karanam, Christopher John Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
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Publication number: 20230062834Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: December 19, 2018Publication date: March 2, 2023Inventors: Daniel Kenneth BONNER, Sifei HAN, Luojuan HU, Ketki KARANAM, Christopher John PORTER, Tim QUACH, Rishab R. SHYAM, Jamie SIMPSON, Natalie TREVASKIS
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Publication number: 20220395513Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: August 4, 2022Publication date: December 15, 2022Applicants: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Rishab R. Shyam, Jamie Simpson, Christopher John Porter, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Publication number: 20220211664Abstract: The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that promote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.Type: ApplicationFiled: March 17, 2022Publication date: July 7, 2022Applicant: Monash UniversityInventors: Chris Porter, Jamie Simpson, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Publication number: 20220143038Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: January 27, 2022Publication date: May 12, 2022Applicants: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
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Publication number: 20220125933Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: February 28, 2020Publication date: April 28, 2022Inventors: Joseph BOLEN, Daniel Kenneth BONNER, Ketki KARANAM, Christopher John PORTER, Jamie SIMPSON, Natalie TREVASKIS, Dan ZHENG, Nathania LEONG, Garima SHARMA, Mitchell MCINERNEY, Tim QUACH, Sifei HAN
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Patent number: 11311512Abstract: The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that promote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.Type: GrantFiled: August 12, 2015Date of Patent: April 26, 2022Assignee: Monash UniversityInventors: Chris Porter, Jamie Simpson, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Patent number: 11304954Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: December 19, 2018Date of Patent: April 19, 2022Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
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Patent number: 11273153Abstract: The present invention relates to certain novel substituted thiophene compounds and the finding that they display useful efficacy in the inhibition of the p38? MAPK enzyme. This provides for use of the compounds in various treatment methodologies related to MAPK inhibition, including the treatment of inflammation.Type: GrantFiled: June 12, 2018Date of Patent: March 15, 2022Assignee: EverBrilliant Pharma Pty LtdInventors: Henry Krum, Peter Scammells, Bing Wang, Natalie Vinh, Jamie Simpson, David Chalmers
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Publication number: 20220001015Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: August 29, 2018Publication date: January 6, 2022Inventors: Daniel Kenneth Bonner, Ketki Karanam, James T. Mutamba, Rishab R. Shyam, Jamie Simpson, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Natalie Trevaskis
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Publication number: 20210300962Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: August 2, 2019Publication date: September 30, 2021Inventors: Daniel Kenneth BONNER, Ketki KARANAM, Jamie SIMPSON, Christopher John PORTER, Natalie TREVASKIS, Tim QUACH, Sifei HAN, Luojuan HU
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Publication number: 20210268115Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: February 5, 2021Publication date: September 2, 2021Inventors: Daniel Kenneth BONNER, Rishab R. SHYAM, Jamie SIMPSON, Christopher John PORTER, Natalie TREVASKIS, Tim QUACH, Sifei HAN, Luojuan HU
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Publication number: 20200390777Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: December 19, 2018Publication date: December 17, 2020Inventors: Daniel Kenneth BONNER, Ketki KARANAM, Sifei HAN, Luojuan HU, Christopher John Hamilton PORTER, Tim QUACH, Rishab R. SHYAM, Jamie SIMPSON, Natalie TREVASKIS