Patents by Inventor Jamie Talisman

Jamie Talisman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8222218
    Abstract: Disclosed are cyclopropanated carbohydrate compounds of formulas I and II: Also disclosed are methods of treating or preventing a central nervous system ailment by administering to an organism in need thereof an effective amount of a cyclopropanated carbohydrate compound of formula I or II and pharmaceutical compositions containing a cyclopropanated carbohydrate compound of formula I or II.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: July 17, 2012
    Assignee: Seton Hall University
    Inventors: Cecilia H. Marzabadi, Ian Jamie Talisman
  • Patent number: 8198313
    Abstract: This invention is directed to indolone derivatives which are antagonists for the GALR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: June 12, 2012
    Assignee: H. Lundbeck A/S
    Inventors: Michael Konkel, John M. Werzel, Jamie Talisman
  • Publication number: 20110178125
    Abstract: This invention is directed to indolone derivatives which are antagonists for the GALR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: January 10, 2011
    Publication date: July 21, 2011
    Inventors: Michael Konkel, John M. Werzel, Jamie Talisman
  • Patent number: 7868034
    Abstract: This invention is directed to indolone derivatives which are antagonists or the GALR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: June 17, 2008
    Date of Patent: January 11, 2011
    Assignee: H. Lundbeck A/S
    Inventors: Michael Konkel, John M. Werzel, Jamie Talisman
  • Publication number: 20090318504
    Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Application
    Filed: December 15, 2008
    Publication date: December 24, 2009
    Inventors: Thomas P. Blackburn, Michael J. Konkel, Lakmal W. Boteju, Ian Jamie Talisman, John M. Wetzel, Mathivanan Packiarajan, Heidi Chen, Hermo Jimenez
  • Publication number: 20090281046
    Abstract: Disclosed are cyclopropanated carbohydrate compounds of formulas I and II: Also disclosed are methods of treating or preventing a central nervous system ailment by administering to an organism in need thereof an effective amount of a cyclopropanated carbohydrate compound of formula I or II and pharmaceutical compositions containing a cyclopropanated carbohydrate compound of formula I or II.
    Type: Application
    Filed: March 27, 2009
    Publication date: November 12, 2009
    Inventors: Cecilia H. Marzabadi, Ian Jamie Talisman
  • Publication number: 20090176840
    Abstract: This invention is directed to indolone derivatives which are antagonists or the GALR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: June 17, 2008
    Publication date: July 9, 2009
    Inventors: Michael Konkel, John M. Werzel, Jamie Talisman
  • Patent number: 7465750
    Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: December 16, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Thomas P. Blackburn, Michael J. Konkel, Lakmal W. Boteju, Ian Jamie Talisman, John M. Wetzel, Mathivanan Packiarajan, Heidi Chen, Hermo Jimenez
  • Publication number: 20070054910
    Abstract: This invention is directed to indolone derivatives which are antagonists for the GALR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: March 23, 2006
    Publication date: March 8, 2007
    Inventors: Michael Konkel, John Wetzel, Jamie Talisman
  • Patent number: 7166635
    Abstract: This invention is directed to indolone derivatives which are selective antagonists for the GalR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: January 23, 2007
    Assignee: H. Lundbeck A/S
    Inventors: Michael Konkel, John M. Wetzel, Jamie Talisman
  • Publication number: 20060172989
    Abstract: This invention is directed to aminoalkoxyphenyl indolone derivatives which are ligands at the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by admixing a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/ or anxiety which comprises administering to the subject an amount of a compound of the subject invention.
    Type: Application
    Filed: February 2, 2005
    Publication date: August 3, 2006
    Inventors: Michael Konkel, Mathivanan Packiarajan, Heidi Chen, Upendra Topiwala, Hermogenes Jimenez, Jamie Talisman
  • Publication number: 20060173180
    Abstract: This invention is directed to aminoalkoxyphenyl indolone derivatives, which are ligands at the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by admixing a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the subject invention.
    Type: Application
    Filed: January 31, 2006
    Publication date: August 3, 2006
    Inventors: Michael Konkel, Mathivanan Packiarajan, Heidi Chen, Upendra Topiwala, Hermogenes Jimenez, Jamie Talisman
  • Patent number: 7081470
    Abstract: This invention is directed to indolone derivatives which are antagonists for the GALR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: July 25, 2006
    Assignee: H. Lundbeck A/S
    Inventors: Michael Konkel, John M. Werzel, Jamie Talisman
  • Publication number: 20050148635
    Abstract: This invention is directed to indolone derivatives which are selective antagonists for the GalR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Application
    Filed: February 28, 2005
    Publication date: July 7, 2005
    Inventors: Michael Konkel, John Wetzel, Jamie Talisman
  • Publication number: 20040127502
    Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Application
    Filed: November 26, 2003
    Publication date: July 1, 2004
    Applicant: Synaptic Pharmaceutical Corporation
    Inventors: Thomas P. Blackburn, Michael J. Konkel, Lakmal W. Boteju, Ian Jamie Talisman, John M. Wetzel, Mathivana Packiarajan, Heidi Chen, Hermo Jimenez
  • Publication number: 20040102507
    Abstract: This invention is directed to indolone derivatives which are antagonists for the GALR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 16, 2003
    Publication date: May 27, 2004
    Inventors: Michael Konkel, John M. Werzel, Jamie Talisman
  • Publication number: 20040082615
    Abstract: This invention is directed to indolone derivatives which are selective antagonists for the GalR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Application
    Filed: August 7, 2003
    Publication date: April 29, 2004
    Inventors: Michael Konkel, John M. Wetzel, Jamie Talisman
  • Publication number: 20030078271
    Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
    Type: Application
    Filed: January 31, 2002
    Publication date: April 24, 2003
    Inventors: Thomas P. Blackburn, Michael J. Konkel, Lakmal W. Boteju, Ian Jamie Talisman, John M. Wetzel, Mathivanan Packiarajan, Heidi Chen, Hermo Jimenez