Patents by Inventor Jamil A. Mashni

Jamil A. Mashni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cleavable agents
    Patent number: 11834416
    Abstract: The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon. Also disclosed herein is a method of cleaving the cleavable agent for enhanced magnetic resonance.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: December 5, 2023
    Assignees: Board of Trustees of Southern Illinois University, Vanderbilt University
    Inventors: Boyd M. Goodson, Eduard Y. Chekmenev, Bryce E. Kidd, Jamil A. Mashni, Miranda Limbach, Yuqing Hou, Fan Shi
  • CLEAVABLE AGENTS
    Publication number: 20230150943
    Abstract: The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon. Also disclosed herein is a method of cleaving the cleavable agent for enhanced magnetic resonance.
    Type: Application
    Filed: January 4, 2023
    Publication date: May 18, 2023
    Applicants: Board of Trustees of Southern Illinois University, Vanderbilt University
    Inventors: Boyd M. Goodson, Eduard Y. Chekmenev, Bryce E. Kidd, Jamil A. Mashni, Miranda Limbach, Yuqing Hou, Fan Shi
  • CLEAVABLE AGENTS
    Publication number: 20200172493
    Abstract: The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon. Also disclosed herein is a method of cleaving the cleavable agent for enhanced magnetic resonance.
    Type: Application
    Filed: November 27, 2019
    Publication date: June 4, 2020
    Applicants: Board of Trustees of Southern Illinois University, Vanderbilt University
    Inventors: Boyd M. Goodson, Eduard Y. Chekmenev, Bryce E. Kidd, Jamil A. Mashni, Miranda Limbach, Yuqing Hou, Fan Shi