Patents by Inventor Jamil S. Saad

Jamil S. Saad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral screening method to identify inhibitors of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P] binding to the HIV gag matrix (MA) protein
    Patent number: 8318419
    Abstract: The present invention provides for testing methods to determine an effective testing agent that affects the activity of the HIV Gag protein at the plasma membrane of a cell, and specifically, effecting changes in the structural conformation of at least one fatty acid of PI(4,5)P2, a member of a family of differentially phosphorylated phosphatidylinositides, wherein inhibition of the extension of such fatty acid into the MA domain of the Gag protein reduces binding of Gag to the plasma membrane, thereby inhibiting virus particle assembly and subsequent replication of the HIV virus.
    Type: Grant
    Filed: July 18, 2008
    Date of Patent: November 27, 2012
    Assignee: University of Maryland, Baltimore County
    Inventors: Michael F. Summers, Jamil S. Saad
  • STRUCTURAL BASIS FOR TARGETING HIV-1 GAG PROTEINS TO THE PLASMA MEMBRANE FOR VIRUS ASSEMBLY
    Publication number: 20090023161
    Abstract: The present invention provides for testing methods to determine an effective testing agent that affects the activity of the HIV Gag protein at the plasma membrane of a cell, and specifically, effecting changes in the structural conformation of at least one fatty acid of PI(4,5)P2, a member of a family of differentially phosphorylated phosphatidylinositides, wherein inhibition of the extension of such fatty acid into the MA domain of the Gag protein reduces binding of Gag to the plasma membrane, thereby inhibiting virus particle assembly and subsequent replication of the HIV virus.
    Type: Application
    Filed: July 18, 2008
    Publication date: January 22, 2009
    Inventors: Michael F. Summers, Jamil S. Saad