Patents by Inventor Jan Adamus

Jan Adamus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of quaternary pyridinium compounds for vasoprotection and/or hepatoprotection
    Patent number: 8377972
    Abstract: The invention relates to a method for the treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury comprising the administration to a patient in a need of such treatment or prevention of a therapeutically or prophylactically effective amount of a compound selected from the group consisting of: wherein R represents hydrogen atom, CH3, OH, pyridyl (C5H4N), 1-methylpyridyl (C5H4N—CH3) or pyridyl substituted with hydroxy group ((OH)C5H3N), and X represents a physiologically acceptable counterion.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: February 19, 2013
    Assignee: Trigendo Sp. zo.o.
    Inventors: Andrzej Marcinek, Stefan Chłopicki, Jerzy Gȩbicki, Jan Adamus
  • Use of Quaternary Pyridinium Compounds for Vasoprotection and/or Hepatoprotection
    Publication number: 20110118316
    Abstract: The invention relates to a method for the treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury comprising the administration to a patient in a need of such treatment or prevention of a therapeutically or prophylactically effective amount of a compound selected from the group consisting of: wherein R represents hydrogen atom, CH3, OH, pyridyl (C5H4N), 1-methylpyridyl (C5H4N—CH3) or pyridyl substituted with hydroxy group ((OH)C5H3N), and X represents a physiologically acceptable counterion.
    Type: Application
    Filed: January 21, 2011
    Publication date: May 19, 2011
    Applicant: TRIGENDO sp. z o.o.
    Inventors: Andrzej MARCINEK, Stefan Chlopicki, Jerzy Gebicki, Jan Adamus
  • N'-NITROXYALKYLNICOTINAMIDES FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
    Publication number: 20110082177
    Abstract: The invention relates to the novel N?-nitroxyalkylnicotinamide derivatives represented by the general formula I wherein R1 is C1-C4 alkyl; R2 is hydrogen. C1-C4 alkyl, CH2OH or CH2ONO2; R3 is ONO2, CH2ONO2 or OH; provided that when R3 is OH, R2 is CH2ONO2; and X? is an organic or inorganic anion; as well as pharmaceutical compositions thereof and their use as a medicament, in particular, in the treatment of diseases of the cardiovascular system.
    Type: Application
    Filed: June 26, 2009
    Publication date: April 7, 2011
    Inventors: Jerzy Gebicki, Andrzej Marcinek, Jan Adamus, Malgorzata Urbaniak, Stefan Chlopicki
  • Use of quaternary pyridinium compounds for vasoprotection and/or hepatoprotection
    Patent number: 7893095
    Abstract: The invention relates to a method for the treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury comprising the administration to a patient in a need of such treatment or prevention of a therapeutically or prophylactically effective amount of a compound selected from the group consisting of: wherein R represents hydrogen atom, CH3, OH, pyridyl (C5H4N), 1-methylpyridyl (C5H4N—CH3) or pyridyl substituted with hydroxy group ((OH)C5H3N), and X represents a physiologically acceptable counterion.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: February 22, 2011
    Assignee: TRIGENDO sp. z o.o.
    Inventors: Andrzej Marcinek, Stefan ChŁopicki, Jerzy GĘbicki, Jan Adamus
  • Use of Quaternary Pyridinium Compounds for Vasoprotection and/or Hepatoprotection
    Publication number: 20080221172
    Abstract: The invention relates to a method for the treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury comprising the administration to a patient in a need of such treatment or prevention of a therapeutically or prophylactically effective amount of a compound selected from the group consisting of: wherein R represents hydrogen atom, CH3, OH, pyridyl (C5H4N), 1-methylpyridyl (C5H4N—CH3) or pyridyl substituted with hydroxy group ((OH)C5H3N), and X represents a physiologically acceptable counterion.
    Type: Application
    Filed: February 27, 2008
    Publication date: September 11, 2008
    Inventors: Andrzej MARCINEK, Stefan Chlopicki, Jerzy Gebicki, Jan Adamus