Patents by Inventor Jan Bastiaan Bouwstra
Jan Bastiaan Bouwstra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7645737Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types.Type: GrantFiled: June 28, 2007Date of Patent: January 12, 2010Assignee: Fuji Film Manufacturing Europe B.V.Inventors: Jan Bastiaan Bouwstra, Andries Johannes Jozef Van Es, Yuzo Toda
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Publication number: 20090264625Abstract: A composition comprising a purified collagen-like polypeptide suitable as a peptizer, said polypeptide comprising [Gly-X-Y]n repeats, wherein Gly stands for glycine, X and Y represent any amino acid and n is an integer and selected such that the length of the [Gly-X-Y]n repeat is at least 2.5 kDa and wherein the amino acid sequence of said [Gly-X-Y]n repeats comprises more than 4 different amino acids and wherein said purified polypeptide is free of helix structure.Type: ApplicationFiled: May 25, 2007Publication date: October 22, 2009Applicant: FUJI MANUFACTURING EURPOE B.V.Inventors: George Valentino Van Heerde, Alexis Comelus Van Rijn, Jan Bastiaan Bouwstra, Frederik Anton De Wolf, Andreas Mooibroek, Marc Willem Theodoor Werten, Richele Deodata Wind, Tanja Jacoba Van Den Bosch
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Patent number: 7598347Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types.Type: GrantFiled: June 28, 2007Date of Patent: October 6, 2009Assignee: Fuji Film Manufacturing Europe B.V.Inventors: Jan Bastiaan Bouwstra, Andries Johannes Jozef Van Es, Yuzo Toda
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Patent number: 7579314Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types.Type: GrantFiled: June 28, 2007Date of Patent: August 25, 2009Assignee: Fuji Film Manufacturing Europe B.V.Inventors: Jan Bastiaan Bouwstra, Andries Johannes Jozef Van Es, Yuzo Toda
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Publication number: 20090186089Abstract: The invention relates to collagenous polypeptide films on which cells are cultivated. In particular the invention relates to such films that are used to treat wounds such as severe burns or physical or chemical injury. The invention also related to methods for producing such films.Type: ApplicationFiled: April 6, 2006Publication date: July 23, 2009Inventors: Raymond Lurvink, Peter Franciscus Theresius Maria van Asten, Jan Bastiaan Bouwstra, Sebastianus Gerardus Johannes Maria Kluijtmans
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Publication number: 20090182063Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types.Type: ApplicationFiled: June 28, 2007Publication date: July 16, 2009Applicant: FUJIFILM MANUFACTURING EUROPE B.V.Inventors: Jan Bastiaan BOUWSTRA, Andries Johannes Jozef VAN ES, Yuzo TODA
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Patent number: 7560427Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types.Type: GrantFiled: June 28, 2007Date of Patent: July 14, 2009Assignee: Fuji Film Manufacturing Europe B.V.Inventors: Jan Bastiaan Bouwstra, Andries Johannes Jozef Van Es, Yuzo Toda
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Publication number: 20090130033Abstract: The invention relates to UV-absorbing polymers, said UV-absorbing polymer comprising a synthetic amine rich polymer to which is covalently linked to an aminobutadiene represented by the general formula (I) wherein the UV-absorbing polymer has a number average molecular weight Mn of 1000 g/mol to 100.000 g/mol; and said UV-absorbing polymer having a UV-absorption of at least 5.6 a.u./g.L at 375 nm.Type: ApplicationFiled: July 25, 2005Publication date: May 21, 2009Inventors: Sebastianus Gerardus Kluijtmans, Jan Bastiaan Bouwstra
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Patent number: 7533629Abstract: The present invention provides an arrangement and method for generating a uniform and stable plasma. The arrangement comprises a discharge space (7) between at least a pair of electrodes (1, 2), which electrodes (1, 2) are arranged for providing an electric field and for generating a plasma in the electric field. At least one of the electrodes (1) has a boundary surface (6) with the discharge space (7). The boundary surface is comprised of one or more alternately arranged conductive (4) and insulating regions (5). The invention further relates to an electrode (1) for use in the arrangement described. The invention may, for example, be used in dielectric barrier discharge configurations, or in arrangements for generating plasmas at atmospheric pressures, or for generating plasmas at low temperatures, such as generating atmospheric pressure glow plasmas (APG) for material processing or surface (3) treatment purposes.Type: GrantFiled: August 13, 2004Date of Patent: May 19, 2009Assignee: Fuji Photo Film B.V.Inventors: Hindrik Willem DeVries, Jan Bastiaan Bouwstra, Eugen Aldea, Mauritius Cornelius Maria Van De Sanden
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Patent number: 7517954Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor dependant cell types.Type: GrantFiled: March 26, 2004Date of Patent: April 14, 2009Assignee: Fuji Film Manufacturing Europe B.V.Inventors: Jan Bastiaan Bouwstra, Andries Johannes Jozef Van Es, Yuzo Toda
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Patent number: 7485205Abstract: Method of generating an atmospheric pressure glow discharge plasma (APG), wherein said plasma is generated in a discharge space formed between at least one first electrode surface and at least one second electrode surface. The method comprises at least the steps of supplying a gaseous substance to said discharge space and powering said first and said second electrode surface for generating said plasma. Said step of supplying a gaseous substance to the discharge space comprises providing at least one intermediate gas supply stream from at least one of said first and second electrode surfaces. The step of supplying said gaseous substance to the discharge space further comprises providing a main gas supply stream for forcing the at least one intermediate gas supply stream in a direction along the first and second electrode surfaces.Type: GrantFiled: August 31, 2004Date of Patent: February 3, 2009Assignee: Fuji Photo Film B.V.Inventors: Hindrik Wilem DeVries, Jan Bastiaan Bouwstra
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Publication number: 20080317974Abstract: Method and arrangement for controlling a discharge plasma in a discharge space (11) having at least two spaced electrodes (13, 14). A gas or gas mixture is introduced in the discharge space (11), and a power supply (15) for energizing the electrodes (13, 14) is provided for applying an AC plasma energizing voltage to the electrodes (13, 14). At least one current pulse is generated and causes a plasma current and a displacement current. Means for controlling the plasma are provided and arranged to apply a displacement current rate of change for controlling local current density variations associated with a plasma variety having a low ratio of dynamic to static resistance, such as filamentary discharges. By damping such fast variations using a pulse forming circuit (20), a uniform glow discharge plasma is obtained.Type: ApplicationFiled: August 24, 2006Publication date: December 25, 2008Inventors: Hindrik Willem de Vries, Eugen Aldea, Jan Bastiaan Bouwstra, Mauritius Cornelius Maria van de Sanden
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Patent number: 7459431Abstract: The invention relates to compositions suitable for plasma substitution comprising as a plasma expander a recombinant gelatin-like protein. Characteristic is that the gelatin-like protein essentially is free of hydroxyproline. This absence of hydroxyproline prevents the composition from gelling and thus allows the use of high-molecular weight proteins in order to establish a suitable colloid osmotic pressure. Specific advantage of the gelatin-like proteins is that these avoid the risk of anaphylactic shock that exists in conjunction with the use of commercially available preparations.Type: GrantFiled: March 6, 2002Date of Patent: December 2, 2008Assignee: Fuji Film Manufacturing Europe B.V.Inventors: Jan Bastiaan Bouwstra, Yuzo Toda
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Publication number: 20080271748Abstract: The present invention relates to a method of and arrangement for removing contaminants from a surface of a substrate by subjecting said substrate surface to an atmospheric pressure glow plasma. Said plasma is generated in a discharge space comprising a plurality of electrodes, by applying an alternating plasma energizing voltage to said electrodes causing a plasma current and a displacement current. Said plasma is stabilised by controlling said displacement current during plasma generation such that modification of properties of said substrate surface is prevented.Type: ApplicationFiled: December 22, 2004Publication date: November 6, 2008Applicant: Fuji Photo Film B.V.Inventors: Hindrik Willem De Vries, Eugen Aldea, Jan Bastiaan Bouwstra, Mauritius Cornelius Maria Van De Sanden
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Publication number: 20080274957Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types.Type: ApplicationFiled: June 28, 2007Publication date: November 6, 2008Applicant: FUJIFILM MANUFACTURING EUROPE B.V.Inventors: Jan Bastiaan BOUWSTRA, Andries Johannes Jozef VAN ES, Yuzo TODA
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Publication number: 20080260661Abstract: The invention relates to the use of an UV-absorbing compound for the preparation of a cosmetic composition for protection against UV radiation said compound being represented by the general formula (I) wherein less than 10% of the total absorption between 250 and 600 nm of said UV-absorbing compound according to formula (I) is above 400 nm. The invention also relates to sunscreen compositions comprising the UV-absorbing compound according to formula (I).Type: ApplicationFiled: August 10, 2005Publication date: October 23, 2008Inventors: Sebastianus Gerardus Johannes Maria Kluijtmans, Akihiko Ikegawa, Jan Bastiaan Bouwstra
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Patent number: 7399944Abstract: The present invention is directed to a method and arrangement for controlling a glow discharge plasma in a gas or gas mixture under atmospheric conditions, in a plasma discharge space comprising at least two spaced electrodes in which at least one plasma pulse having an absolute pulse maximum is generated by applying an AC plasma energizing voltage to the electrodes causing a plasma current and a displacement current. The plasma is controlled by providing a relative decrease of the displacement current after the pulse maximum. In a preferred embodiment, the energizing voltage is applied through a series circuit including a choke coil and a non-saturable inductor.Type: GrantFiled: August 12, 2005Date of Patent: July 15, 2008Assignee: Fuji Photo Film B.V.Inventors: Hindrik Willem DeVries, Yoichiro Kamiyama, Jan Bastiaan Bouwstra, Mauritius Cornelius Maria Van de Sanden, Eugen Aldea, Paul Peeters
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Publication number: 20080167446Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types.Type: ApplicationFiled: June 28, 2007Publication date: July 10, 2008Applicant: FUJIFILM MANUFACTURING EUROPE B.V.Inventors: Jan Bastiaan BOUWSTRA, Andries Johannes Jozef VAN ES, Yuzo TODA
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Publication number: 20080113910Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types.Type: ApplicationFiled: June 28, 2007Publication date: May 15, 2008Applicant: FUJIFILM MANUFACTURING EUROPE B.V.Inventors: Jan Bastiaan BOUWSTRA, Andries Johannes Jozef VAN ES, Yuzo TODA
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Publication number: 20080114078Abstract: The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types.Type: ApplicationFiled: June 28, 2007Publication date: May 15, 2008Applicant: FUJIFILM MANUFACTURING EUROPE B.V.Inventors: Jan Bastiaan BOUWSTRA, Andries Johannes Jozef VAN ES, Yuzo TODA