Abstract: The present invention resides in a multichannel head of a pipetting device for aspirating and dispensing liquid via a plurality of pipetting tips. The multichannel head comprises a connector block (110) having an array of m*n connectors (120), whereby each connector comprises an internal passageway (125) that is fluidically connectable to a pipetting tip, and further includes a plunger block having a corresponding array of m*n channels. Each channel accommodates a plunger and has an opening that is fluidically connected to the internal passageway (125) of a corresponding connector. The multichannel head further comprises a sealing mat (150) arranged between the connector block (110) and the plunger block, wherein the sealing mat comprises a corresponding array of men annular sealing elements for providing an airtight seal of the fluidic connection between the internal passageway of each connector and each opening of the corresponding plunger channel.