Abstract: The present disclosure relates to treating a subject comprising administering to the subject a therapy (e.g., a cell therapy, e.g., an adoptive cell therapy, e.g., a CAR-T cell therapy), wherein, prior to the administration, the subject has been preconditioned with a personalized amount of a chemotherapeutic agent. The personalized amount provides an optimal exposure to the chemotherapeutic agent.

Abstract: The invention relates to a process for the preparation of hydrocarbons by a catalytic reaction of a mixture of carbon monoxide and hydrogen, comprising the steps of:(i) providing a gas mixture comprising carbon monoxide and hydrogen;(ii) washing the mixture with an aqueous solution for the removal of impurities from the mixture;(iii) removing the washing solution containing the impurities from the mixture;(iv) contacting the washed mixture with a catalyst whereby hydrocarbons and reaction water are formed;(v) separating the reaction water from the hydrocarbons; and(vi) using reaction water as aqueous solution in washing step (ii)and to hydrocarbons obtained therewith.