Abstract: Methods for computing hemodynamic quantities include: (a) acquiring angiography data from a patient; (b) calculating a flow and/or calculating a change in pressure in a blood vessel of the patient based on the angiography data; and (c) computing the hemodynamic quantity based on the flow and/or the change in pressure. Systems for computing hemodynamic quantities and computer readable storage media are described.

Abstract: A method and system for virtual percutaneous valve implantation is disclosed. A patient-specific anatomical model of a heart valve is estimated based on 3D cardiac medical image data and an implant model representing a valve implant is virtually deployed into the patient-specific anatomical model of the heart valve. A library of implant models, each modeling geometrical properties of a corresponding valve implant, is maintained. The implant models maintained in the library are virtually deployed into the patient specific anatomical model of the heart valve to select an implant type and size and deployment location and orientation for percutaneous valve implantation.

Abstract: Methods for computing hemodynamic quantities include: (a) acquiring angiography data from a patient; (b) calculating a flow and/or calculating a change in pressure in a blood vessel of the patient based on the angiography data; and (c) computing the hemodynamic quantity based on the flow and/or the change in pressure. Systems for computing hemodynamic quantities and computer readable storage media are described.

Abstract: A method and system for autoregressive model based pigtail catheter motion prediction in a fluoroscopic image sequence is disclosed. Parameters of an autoregressive model are estimated based on observed pigtail catheter tip positions in a plurality of previous frames of a fluoroscopic image sequence. A pigtail catheter tip position in a current frame of the fluoroscopic image sequence is predicted using the fitted autoregressive model. The predicted pigtail catheter tip position can be used to constrain pigtail catheter tip detection in the current frame. The predicted pigtail catheter tip position may also be used to predict abnormal motion in the fluoroscopic image sequence.

Abstract: A method and system for fusion of multi-modal volumetric images is disclosed. A first image acquired using a first imaging modality is received. A second image acquired using a second imaging modality is received. A model and of a target anatomical structure and a transformation are jointly estimated from the first and second images. The model represents a model of the target anatomical structure in the first image and the transformation projects a model of the target anatomical structure in the second image to the model in the first image. The first and second images can be fused based on estimated transformation.

Abstract: A method and system for aorta segmentation in a 3D volume, such as a C-arm CT volume is disclosed. The aortic root is detected in the 3D volume using marginal space learning (MSL) based segmentation. The aortic arch is detected in the 3D volume using MSL based segmentation. The ascending aorta is tracked from the aortic root to the aortic arch in the 3D volume, and the descending aorta is tracked from the aortic arch in the 3D volume.

Abstract: A method and system for registering ultrasound images and physiological models to x-ray fluoroscopy images is disclosed. A fluoroscopic image and an ultrasound image, such as a Transesophageal Echocardiography (TEE) image, are received. A 2D location of an ultrasound probe is detected in the fluoroscopic image. A 3D pose of the ultrasound probe is estimated based on the detected 2D location of the ultrasound probe in the fluoroscopic image. The ultrasound image is mapped to a 3D coordinate system of a fluoroscopic image acquisition device used to acquire the fluoroscopic image based on the estimated 3D pose of the ultrasound probe. The ultrasound image can then be projected into the fluoroscopic image using a projection matrix associated with the fluoroscopic image. A patient specific physiological model can be detected in the ultrasound image and projected into the fluoroscopic image.

Abstract: A method and system for extracting a silhouette of a 3D mesh representing an anatomical structure is disclosed. The 3D mesh is projected to two dimensions. Silhouette candidate edges are generated in the projected mesh by pruning edges and mesh points based on topology analysis of the projected mesh. Each silhouette candidate edge that intersects with another edge in the projected mesh is split into two silhouette candidate edges. The silhouette is extracted using an edge following process on the silhouette candidate edges.

Abstract: The left ventricle epicardium is estimated in medical diagnostic imaging. C-arm x-ray data is used to detect an endocardium at different phases. The detected endocardium at the different phases is compared to sample endocardiums at different phases. The sample endocardiums have corresponding sample epicardiums. The transformation between the most similar sample endocardium or endocardiums over time and the detected endocardium over time is applied to the corresponding sample epicardium or epicardiums. The transformed sample epicardium over time is the estimated epicardium over time for the C-arm x-ray data.

Abstract: Methods for computing hemodynamic quantities include: (a) acquiring angiography data from a patient; (b) calculating a flow and/or calculating a change in pressure in a blood vessel of the patient based on the angiography data; and (c) computing the hemodynamic quantity based on the flow and/or the change in pressure. Systems for computing hemodynamic quantities and computer readable storage media are described.

Abstract: Methods, systems, and apparatus for obtaining a sequence of x-ray images are disclosed. An object of interest in a first x-ray image is detected and an area of interest, based on a predicted motion of the object of interest, is determined. A second x-ray image of the area of interest is acquired using spatial x-ray modification to control an x-ray to pass through a portion of a patient corresponding to the area of interest.

Abstract: Methods for computing hemodynamic quantities include: (a) acquiring angiography data from a patient; (b) calculating a flow and/or calculating a change in pressure in a blood vessel of the patient based on the angiography data; and (c) computing the hemodynamic quantity based on the flow and/or the change in pressure. Systems for computing hemodynamic quantities and computer readable storage media are described.

Abstract: A method (10) to compensate for cardiac and respiratory motion in cardiac imaging during minimal invasive (e.g., trans-catheter) AVI procedures by image-based tracking (20, 25) on fluoroscopic images.

Abstract: An X-ray imaging apparatus has at least one X-ray image system rotatable about an examination volume. The X-ray image system is controlled such that during a continuous rotation of the system, at least one 2D projection image is recorded. An image generation facility generates the 2D projection image from the measured data. The X-ray source includes an X-ray focus which can be changed in terms of position, which, during the recording of the 2D projection image, moves counter to the direction of rotation of the X-ray image system such that its spatial position in a fixed coordinate system does not change. The X-ray detector records several 2D partial images, from which the 2D projection image is calculated with the rotational movement of the X-ray detector being at least approximately compensated. The 2D projection images have significantly reduced image blur.

Abstract: Background information is subtracted from projection data in medical diagnostic imaging. The background is removed using data acquired in a single rotational sweep of a C-arm. The removal may be by masking out a target, leaving the background, in the data as constructed into a volume. For subtraction, the masked background information is projected to a plane and subtracted from the data representing the plane.

Abstract: A method and system for adaptive discriminant learning and measurement fusion for image based catheter tracking is disclosed. An adaptive discriminant model is trained online based on a tracked object, such as a pigtail catheter tip, in at least one previous frame of a fluoroscopic image sequence. The object is tracked in the current frame of the fluoroscopic image sequence based at least on the adaptive discriminant model trained online. The object may be tracked in the current frame based on a fusion of three types of measurement models including the adaptive discriminant model trained online, an object detection model trained offline, and an online appearance model.

Abstract: A system and method for performing shape-constrained aortic valve landmark detection using 3D medical images is provided. A rigid global shape defining initial positions of a plurality of aortic valve landmarks is detected within a 3D image. Each of the plurality of aortic valve landmarks is detected based on the initial positions.

Abstract: The invention relates to a mapping catheter for determination of data of an area of an organ embodied as a flat surface, especially of the heart, to be presented graphically, with at least one thermosensor essentially aligned in the direction of the longitudinal axis of the mapping catheter for determination of temperature-related data which is arranged at a tip of the mapping catheter being provided in the distal area of the mapping catheter for introduction into the organ.

Abstract: A method and system for estimating 3D cardiac motion from a single C-arm angiography scan is disclosed. An initial 3D volume is reconstructed from a plurality of 2D projection images acquired in a single C-arm scan. A static mesh is extracted by segmenting an object in the initial 3D volume. The static mesh is projected to each of the 2D projection images. A cardiac phase is determined for each of the 2D projection images. A deformed mesh is generated for each of a plurality of cardiac phases based on a 2D contour of the object and the projected mesh in each of the 2D projection images of that cardiac phase.

Abstract: The invention relates to an operating method for an imaging system for the time-resolved mapping of an iteratively moving examination object. First recordings of the object are generated by the imaging system from various angles while simultaneously recording a phase signal. Multiple static 3D-image data sets corresponding to a sequence of defined phases are reconstructed from the first recordings. Three-dimensional motion fields are calculated from the 3D-image data sets, by which two 3D-image data sets are mapped onto one another. Second recordings of the object are generated by the imaging system from various angles while simultaneously recording a phase signal. 3D-image data sets from the second recordings in a previously determined reference phase of the phase signal using the motion fields is generated which is a sequence of motion-compensated 3D-image data sets.