Abstract: An asphalt mixture comprising an oligoterpene composition and reclaimed asphalt and/or virgin asphalt, a method of preparing said asphalt mixture, a bituminous binder-oligoterpene blend and a method for rejuvenating reclaimed asphalt or treating virgin asphalt are disclosed, wherein the oligoterpene composition comprises at least one oligoterpene with at least two isoprene moieties selected from a diterpene, a triterpene, a tetraterpene, a pentaterpene and a hexaterpene. The method of preparing an asphalt mixture comprises mixing the oligoterpene composition with reclaimed asphalt and/or virgin asphalt. The oligoterpene-bituminous binder blend, comprises 0.5-50 wt. % of the oligoterpene composition based on the total weight of the blend. The method for rejuvenating reclaimed asphalt or treating virgin asphalt comprises mixing the oligoterpene composition with reclaimed asphalt or virgin asphalt to form a modified asphalt.

Abstract: The invention provides a process for the production of a (particulate) luminescent material comprising particles, especially substantially spherical particles, having a porous inorganic material core with pores, especially macro pores, which are at least partly filled with a polymeric material with a first material embedded therein, wherein the process comprises (i) impregnating the particles of a particulate porous inorganic material with pores with a first liquid (“ink”) comprising the first material and a curable or polymerizable precursor of the polymeric material, to provide pores that are at least partly filled with said first material and curable or polymerizable precursor; and (ii) curing or polymerizing the curable or polymerizable precursor within pores of the porous material, as well as a product obtainable thereby.

Abstract: A method and apparatus for cleaning the inside of an immersion lithographic apparatus is disclosed. In particular, a liquid supply system of the lithographic apparatus may be used to introduce a cleaning fluid into a space between the projection system and the substrate table of the lithographic apparatus. Additionally or alternatively, a cleaning device may be provided on the substrate table and an ultrasonic emitter may be provided to create an ultrasonic cleaning liquid.

Abstract: One aspect of the invention relates to a biocompatible, covalently cross-linked, polymer that is obtained by reacting an electrophilically activated polyoxazoline (EL-POX) with a nucleophilic cross-linking agent, said electrophilically activated POX comprising m electrophilic groups; and said nucleophilic cross-linking agent comprising n nucleophilic groups, wherein the m electrophilic groups are capable of reaction with the n nucleophilic groups to form covalent bonds; wherein m?2, n?2 and m+n?5; wherein at least one of the m electrophilic groups is a pendant electrophilic group and/or wherein m?3; and wherein the EL-POX comprises an excess amount of electrophilic groups relative to the amount of nucleophilic groups contained in the nucleophilic cross-linking agent. The invention further relates to biocompatible medical products comprising such a cross-linked POX-polymer. Also provided is a kit for producing a biocompatible, cross-linked POX-polymer.

Abstract: A biocompatible, covalently cross-linked, polymer that is obtained by reacting an electrophilically activated polyoxazoline (EL-PDX) with a nucleophilic cross-linking agent is disclosed. The EL-PDX comprises m electrophilic groups; and the nucleophilic cross-linking agent comprises n nucleophilic groups, wherein the m electrophilic groups are capable of reacting with the n nucleophilic groups to form covalent bonds; wherein m?2, n?2 and m+n?5; wherein at least one of the m electrophilic groups is a pendant electrophilic group and/or wherein m?3; and wherein the EL-PDX comprises an excess amount of electrophilic groups relative to the amount of nucleophilic groups contained in the nucleophilic cross-linking agent. Biocompatible medical products and kits comprising the cross-linked PDX-polymers are also disclosed.

Abstract: A method and apparatus for cleaning the inside of an immersion lithographic apparatus is disclosed. In particular, a liquid supply system of the lithographic apparatus may be used to introduce a cleaning fluid into a space between the projection system and the substrate table of the lithographic apparatus. Additionally or alternatively, a cleaning device may be provided on the substrate table and an ultrasonic emitter may be provided to create an ultrasonic cleaning liquid.

Abstract: A measuring device for measuring physiological data of a mammal comprising a measuring unit, to be worn by the mammal, with a first and second module. The first module comprises a light source and the second module comprises a sensor unit for measuring an intensity of a fraction of the light delivering a measuring signal. There is a synchronization means for pulsewise activating the light source synchronously with the second module, wherein the measuring signal is indicative of the value of the intensity measured during the pulsewise activation. The synchronization means comprises an energy transmitting unit and a detector which is part of the other one of the first and the second module, in an operating condition the energy transmitting unit pulsewise generates an electromagnetic field, and the detector receives this field and generates therefrom a supply voltage for use in that other module.

Abstract: The invention is generally directed to modified filamentous fungal host cells comprising one or more nucleic acids encoding one or more polypeptides under the control of one or more promoters that are functional in said cells. Methods of using the modified cells to express one or more polypeptides are also disclosed, including methods of screening cells transformed with one or more expression vectors comprising nucleic acids derived from synthetic or genomic nucleic acids including, cDNAs. Methods of purifying one or more polypeptides or complexes comprising one or more polypeptides expressed in the modified cells, intended for use as substrates in structure/function studies, as therapeutic agents, as diagnostic reagents, or as human or animal vaccines, are also disclosed.

Abstract: Psicose is converted into 5-hydroxymethylfurfural or an alkyl ether thereof in a process for the catalysed conversion of psicose, including the steps of: a. forming a feed including psicose and water or at least one alkanol or a mixture thereof and b. converting the psicose in the feed at a temperature in the range of 50 to 300 degrees Celsius in the presence of a catalyst.

Abstract: Composition including a first component, including furfuryl alcohol and humins and a second component including an acidic polymerization initiator. The composition can be oligomerized to a resin, which has a viscosity in the range of 0.1 to 10,000 Pa·s at 25° C., determined according to ISO3219. The resin, or a blend of furfuryl alcohol and humins as a component A and an acidic polymerization initiator as a component B, separated from each other, may form a kit for an adhesive or impregnation agent.

Abstract: A flat-bottomed vessel for transporting persons or goods, the vessel including a drag reduction system attached to the bottom of the vessel. The drag reduction system includes: two or more turbulence members extending perpendicular to the longitudinal direction of the vessel for generating an area with turbulent flow downstream to the turbulence members at the bottom of the vessel during movement. Additionally, for each turbulence member an air injector can be used to inject an air flow at or near to the turbulence members.

Abstract: One aspect of the invention relates to a biocompatible medical product comprising at least 1% by weight of dry matter of a covalently cross-linked polymer that is obtained by reacting a nucleophilically activated polyoxazoline (NU-PDX) with an electrophilic cross-linking agent other than an electrophilically activated polyoxazoline, said NU-PDX comprising m nucleophilic groups; and said electrophilic cross-linking agent comprising n electrophilic groups, wherein the m nucleophilic groups are capable of reaction with the n electrophilic groups to form covalent bonds; wherein m?2, n?2 and m+n?5; and wherein the NU-PDX comprises at least 30 oxazoline units in case the electrophilic cross-linking agent is an isocyanate. Also provided is a kit for producing the aforementioned biocompatible cross-linked polymer. The biocompatible cross-linked polymers according to the invention have excellent implant and/or sealing characteristics.

Abstract: In a process for carrying out a reaction, a liquid reaction mixture is contacted with a catalyst that includes silica and/or a silicate, in which process a silicon compound that is soluble in the liquid reaction mixture is added to the reaction mixture before being contacted with the catalyst. The aqueous reaction mixture suitably contains water, an alcohol or a mixture thereof.

Abstract: One aspect of the invention relates to a biocompatible medical product comprising at least 1% by weight of dry matter of a covalently cross-linked polymer that is obtained by reacting a nucleophilically activated polyoxazoline (NU-POX) with an electrophilic cross-linking agent other than an electrophilically activated polyoxazoline, said NU-POX comprising m nucleophilic groups; and said electrophilic cross-linking agent comprising n electrophilic groups, wherein the m nucleophilic groups are capable of reaction with the n electrophilic groups to form covalent bonds; wherein m?2, n?2 and m+n?5; and wherein the NU-POX comprises at least 30 oxazoline units in case the electrophilic cross-linking agent is an isocyanate. Also provided is a kit for producing the aforementioned biocompatible cross-linked polymer. The biocompatible cross-linked polymers according to the invention have excellent implant and/or sealing characteristics.

Abstract: The invention relates to a substituted azadibenzocyclooctyne compound according to Formula (5): The invention also relates to a conjugate wherein a substituted azadibenzocyclooctyne according to the invention is conjugated to a label, and to the use of these conjugates for bioorthogonal labeling, imaging or modification of a target molecule, e.g. surface modification. The invention further relates to a method for the modification of a target molecule, wherein a conjugate according to the invention is reacted with a compound comprising a 1,3-dipole or a 1,3-(hetero)diene.

Abstract: The invention provides a process for the production of a (particulate) luminescent material comprising particles, especially substantially spherical particles, having a porous inorganic material core with pores, especially macro pores, which are at least partly filled with a polymeric material with luminescent quantum dots embedded therein, wherein the process comprises (i) impregnating the particles of a particulate porous inorganic material with pores with a first liquid (“ink”) comprising the luminescent quantum dots and a curable or polymerizable precursor of the polymeric material, to provide pores that are at least partly filled with said luminescent quantum dots and curable or polymerizable precursor; and (ii) curing or polymerizing the curable or polymerizable precursor within pores of the porous material, as well as a product obtainable thereby.

Abstract: The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ?-glucanase and endogenous cellobiohydrolase is less than 20% of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75%, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed.

Abstract: A method of data communication with a selected sensor of multiple liquid level detection sensors connected to a central processing unit includes the steps of: a) transmitting by the central processing unit directly or indirectly a communication signal to the selected sensor of the series of multiple sensors, b) upon receipt of the communication signal by the selected sensor, processing the communication signal in the selected sensor. A liquid level detection system, in particular a liquid overfill prevention system for multi compartment liquid tank trucks, includes two or more liquid level detection sensors, preferably arranged in series, and a central processing unit, where at least one of the two or more sensors includes a sensor processing unit comprising a storage unit.

Abstract: An optical liquid level detection sensor includes a light source for emitting a light beam, a liquid contact surface, and a light detector, where the light source is arranged to emit a light beam towards the liquid contact surface, which liquid contact surface reflects or transmits the light beam in dependence of liquid being present on the liquid contact surface, where the light detector is arranged to receive the light beam after reflection on the liquid contact surface, where the sensor includes an at least partially transparent ring element, and where the liquid contact surface is formed by an outer surface of the ring element.

Abstract: The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ?-glucanase and endogenous cellobiohydrolase is less than 20% of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75%, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed.