Patents by Inventor Jan Edward Thirkettle

Jan Edward Thirkettle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing crystallized pleuromutilins
    Patent number: 7556948
    Abstract: Invented are non-peptide TPO mimetics. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: July 7, 2009
    Assignee: Glaxo Group Limited
    Inventors: Michael John Rees, Keith Graham Robins, Anna Louisa Stefanska, Jan Edward Thirkettle, Michael Sidney Verrall, David Alan Yeandle
  • Process for preparing clavam derivatives by using polypeptides having ?-lactam synthetase activity
    Patent number: 6905849
    Abstract: The present invention relates to a new process for the synthesis of clavam compounds, in particular clavulanic acid. In one aspect, the invention relates to Streptomyces clavuligerus ?-lactam synthetase polypeptide sand Streptomyces clavuligerus ?-lactam synthetase polynucleotides, recombinant materials thereof and methods for their production. In another aspect, the invention relates to methods for using such polypeptides and polynucleotides.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: June 14, 2005
    Assignee: SmithKline Beecham plc
    Inventors: Barry Barton, Heather Jane McNaughton, Christopher Joseph Schofield, Jan Edward Thirkettle