Abstract: A printing process for dosage forms selected from hard or soft capsules, the process comprising the steps of: (i) providing a plurality of said dosage forms, preferably filled with a liquid composition, in a reservoir; (ii) transferring a predetermined number of the dosage forms from said reservoir to a printing station; (iii) printing indicia over each of the dosage forms; (iv) transferring the printed dosage forms to an inspection station arranged to sense a predetermined characteristic of the indicia; (v) sorting the dosage forms based on the sensed predetermined characteristic of the indicia by separating dosage forms that meet the predetermined characteristics from dosage forms that do not meet the predetermined characteristics; wherein the dosage forms that do not meet the predetermined characteristics are collected and further processed through a regenerating unit arranged to remove the indicia from the dosage forms in a regeneration step, and further re-processed according to steps (i) to (v).

Abstract: A printing process for dosage forms selected from hard or soft capsules, the process comprising the steps of: (i) providing a plurality of said dosage forms, preferably filled with a liquid composition, in a reservoir; (ii) transferring a predetermined number of the dosage forms from said reservoir to a printing station; (iii) printing indicia over each of the dosage forms; (iv) transferring the printed dosage forms to an inspection station arranged to sense a predetermined characteristic of the indicia; (v) sorting the dosage forms based on the sensed predetermined characteristic of the indicia by separating dosage forms that meet the predetermined characteristics from dosage forms that do not meet the predetermined characteristics; wherein the dosage forms that do not meet the predetermined characteristics are collected and further processed through a regenerating unit arranged to remove the indicia from the dosage forms in a regeneration step, and further re-processed according to steps (i) to (v).

Abstract: A novel gelatin comprising dosage form article for oral administration and for containing therein a fill composition, the fill composition comprising one or more active materials capable of reacting with gelatin, and optionally one or more excipient materials, wherein the dosage form is made of a gelatin material and one or more plasticizers, the gelatin material having a mean molecular weight of less than about 130,000 g/mol and a low microgel content, wherein the fraction of microgel is of less than about 10% of the total number of gelatin chains of the gelatin material.

Abstract: Novel delivery systems for highly hygroscopic active materials is disclosed. The delivery system comprising a hard capsule filled with a liquid composition consisting of a hygroscopic active material dispersed in a non-aqueous carrier. The carrier comprising, or consisting of, one or more lipophilic lipid substances and one or more rheology modifiers.

Abstract: A novel gelatin comprising dosage form article for oral administration and for containing therein a fill composition, the fill composition comprising one or more active materials capable of reacting with gelatin, and optionally one or more excipient materials, wherein the dosage form is made of a gelatin material and one or more plasticizers, the gelatin material having a mean molecular weight of less than about 130,000 g/mol and a low microgel content, wherein the fraction of microgel is of less than about 10% of the total number of gelatin chains of said gelatin material.

Abstract: The present invention relates to a novel liquid delivery carrier comprising a specific grade of glyceryl caprylate and PEG-40 hydrogenated castor oil in particular amounts. This carrier can be loaded with slightly or poorly water soluble substances and filled into hard gelatin capsule shells for final administration to a subject. Also disclosed are filling compositions comprising such delivery carrier and hard gelatin capsules filled with the carrier and the composition of the invention. The delivery carrier of the invention proved to be compatible with both the hard gelatin capsule shells and the substances loaded into it.

Abstract: The present invention relates to a novel liquid delivery carrier comprising a specific grade of glyceryl caprylate and PEG-40 hydrogenated castor oil in particular amounts. This carrier can be loaded with slightly or poorly water soluble substances and filled into hard gelatin capsule shells for final administration to a subject. Also disclosed are filling compositions comprising such delivery carrier and hard gelatin capsules filled with the carrier and the composition of the invention. The delivery carrier of the invention proved to be compatible with both the hard gelatin capsule shells and the substances loaded into it.