Patents by Inventor Jan Groen

Jan Groen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9834824
    Abstract: Provided is an isolated mammalian negative strand RNA virus, metapneumovirus (MPV), within the sub-family Pneumoviridae, of the family Paramyxoviridae. Also provided are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. In particular, provided is a mammalian MPV, subgroups and variants thereof. Also provided are genomic nucleotide sequences of different isolates of mammalian MPV, in particular, human MPV. Disclosed is the use of the sequence information of different isolates of mammalian MPV for diagnostic and therapeutic methods. Provided are nucleotide sequences encoding the genome of an MPV or a portion thereof, including both mammalian and avian MPV. Further described are chimeric or recombinant viruses encoded by the nucleotide sequences and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: December 5, 2017
    Assignee: ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM
    Inventors: Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Cornelius De Jong, Jan Groen
  • Patent number: 9803252
    Abstract: The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: October 31, 2017
    Assignee: ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM
    Inventors: Jan Cornelius De Jong, Ronaldus Adrianus Maria Fouchier, Jan Groen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Bernadetta Gerarda Van Den Hoogen
  • Publication number: 20170183747
    Abstract: The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
    Type: Application
    Filed: March 8, 2017
    Publication date: June 29, 2017
    Applicant: Erasmus University Medical Center Rotterdam
    Inventors: Jan Cornelius De Jong, Ronaldus Adrianus Maria Fouchier, Jan Groen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Bernadetta Gerarda Van Den Hoogen
  • Publication number: 20170137899
    Abstract: Provided is an isolated mammalian negative strand RNA virus, metapneumovirus (MPV), within the sub-family Pneumoviridae, of the family Paramyxoviridae. Also provided are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. In particular, provided is a mammalian MPV, subgroups and variants thereof. Also provided are genomic nucleotide sequences of different isolates of mammalian MPV, in particular, human MPV. Disclosed is the use of the sequence information of different isolates of mammalian MPV for diagnostic and therapeutic methods. Provided are nucleotide sequences encoding the genome of an MPV or a portion thereof, including both mammalian and avian MPV. Further described are chimeric or recombinant viruses encoded by the nucleotide sequences and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences.
    Type: Application
    Filed: January 12, 2017
    Publication date: May 18, 2017
    Applicant: Erasmus University Medical Center Rotterdam
    Inventors: Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Cornelius De Jong, Jan Groen
  • Patent number: 9593386
    Abstract: The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: March 14, 2017
    Assignee: ERASMUS UNIVERSITEIT MEDICAL CENTER ROTTERDAM
    Inventors: Jan Cornelius De Jong, Ronaldus Adrianus Maria Fouchier, Jan Groen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Bernadetta Gerarda Van Den Hoogen
  • Patent number: 9567653
    Abstract: Provided is an isolated mammalian negative strand RNA virus, metapneumovirus (MPV), within the sub-family Pneumoviridae, of the family Paramyxoviridae. Also provided are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. In particular, provided is a mammalian MPV, subgroups and variants thereof. Also provided are genomic nucleotide sequences of different isolates of mammalian MPV, in particular, human MPV. Disclosed is the use of the sequence information of different isolates of mammalian MPV for diagnostic and therapeutic methods. Provided are nucleotide sequences encoding the genome of an MPV or a portion thereof, including both mammalian and avian MPV. Further described are chimeric or recombinant viruses encoded by the nucleotide sequences and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: February 14, 2017
    Assignee: Erasmus University Medical Center Rotterdam
    Inventors: Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Cornelius De Jong, Jan Groen
  • Publication number: 20160244850
    Abstract: The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
    Type: Application
    Filed: May 5, 2016
    Publication date: August 25, 2016
    Applicant: Erasmus Universiteit Medical Center Rotterdam
    Inventors: Jan Cornelius De Jong, Ronaldus Adrianus Maria Fouchier, Jan Groen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Bernadetta Gerarda Van Den Hoogen
  • Patent number: 9334543
    Abstract: The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: May 10, 2016
    Assignee: Erasmus University Medical Center Rotterdam
    Inventors: Jan Cornelius De Jong, Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus D M E Osterhaus, Jan Groen
  • Publication number: 20150343605
    Abstract: A method of manufacturing a flexible grinding product comprises the steps: a) preparing an open cloth of knitted or woven fabric; b) applying a coating to one surface of the cloth, wherein the coated surface of the cloth has one or more flat portions; c) applying a grinding agent to the coated surface of the cloth. Further, a flexible grinding product has an open cloth, wherein a surface of the cloth is provided with a coating such that the coated surface has one or more flat areas which are at least partially provided with a grinding agent.
    Type: Application
    Filed: September 5, 2012
    Publication date: December 3, 2015
    Inventors: Göran Höglund, Hans HEDE, Nicolas SCHUMACHER, Mats SUNDELL, Jan GRÖN
  • Publication number: 20150093746
    Abstract: The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
    Type: Application
    Filed: November 25, 2014
    Publication date: April 2, 2015
    Inventors: Jan Cornelius De Jong, Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus D M E Osterhaus, Jan Groen
  • Patent number: 8927206
    Abstract: The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single stranded RNA virus (MPV) within the sub-family Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: January 6, 2015
    Assignee: ViroNovative B.V.
    Inventors: Jan Cornelius De Jong, Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Groen
  • Publication number: 20140370497
    Abstract: Provided is an isolated mammalian negative strand RNA virus, metapneumovirus (MPV), within the sub-family Pneumoviridae, of the family Paramyxoviridae. Also provided are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. In particular, provided is a mammalian MPV, subgroups and variants thereof. Also provided are genomic nucleotide sequences of different isolates of mammalian MPV, in particular, human MPV. Disclosed is the use of the sequence information of different isolates of mammalian MPV for diagnostic and therapeutic methods. Provided are nucleotide sequences encoding the genome of an MPV or a portion thereof, including both mammalian and avian MPV. Further described are chimeric or recombinant viruses encoded by the nucleotide sequences and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences.
    Type: Application
    Filed: August 14, 2014
    Publication date: December 18, 2014
    Inventors: Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Cornelius De Jong, Jan Groen
  • Patent number: 8841433
    Abstract: Provided is an isolated mammalian negative strand RNA virus, metapneumovirus (MPV), within the sub-family Pneumoviridae, of the family Paramyxoviridae. Also provided are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. In particular, provided is a mammalian MPV, subgroups and variants thereof. Also provided are genomic nucleotide sequences of different isolates of mammalian MPV, in particular, human MPV. Disclosed is the use of the sequence information of different isolates of mammalian MPV for diagnostic and therapeutic methods. Provided are nucleotide sequences encoding the genome of a MPV or a portion thereof, including both mammalian and avian MPV. Further described are chimeric or recombinant viruses encoded by the nucleotide sequences, and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: September 23, 2014
    Assignee: ViroNovative BV
    Inventors: Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Cornelius De Jong, Jan Groen
  • Patent number: 8715922
    Abstract: The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: May 6, 2014
    Assignee: ViroNovative
    Inventors: Jan Cornelius De Jong, Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Groen
  • Patent number: 8318423
    Abstract: The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of human rhinovirus (HRV) in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved 5? untranslated region of the HRV genome. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: November 27, 2012
    Assignee: Focus Diagnostics, Inc.
    Inventors: Ming-Chou Lee, Lilly I Kong, Jan Groen
  • Patent number: 8119338
    Abstract: The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of human rhinovirus (HRV) in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved 5? untranslated region of the HRV genome. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention.
    Type: Grant
    Filed: October 15, 2007
    Date of Patent: February 21, 2012
    Assignee: Focus Diagnostics, Inc.
    Inventors: Ming Chou Lee, Lilly Kong, Jan Groen
  • Publication number: 20090246855
    Abstract: The present invention provides an isolated mammalian negative strand RNA virus, metapneumovirus (MPV), within the sub-family Pneumoviridae, of the family Paramyxoviridae. The invention also provides isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. In particular the invention provides a mammalian MPV, subgroups and variants thereof. The invention relates to genomic nucleotide sequences of different isolates of mammalian metapneumoviruses, in particular human metapneumoviruses. The invention relates to the use of the sequence information of different isolates of mammalian metapneumoviruses for diagnostic and therapeutic methods. The present invention relates to nucleotide sequences encoding the genome of a metapneumovirus or a portion thereof, including both mammalian and avian metapneumovirus. The invention further encompasses chimeric or recombinant viruses encoded by said nucleotide sequences.
    Type: Application
    Filed: September 18, 2008
    Publication date: October 1, 2009
    Inventors: Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Cornelius De Jong, Jan Groen
  • Patent number: 7516863
    Abstract: A liner for a container has an upper wall, a bottom wall as well as a front wall, a rear wall and side walls interconnecting the upper wall and the bottom wall. Straps extending over the front wall are provided, which straps are provided with extensions extending outside the front wall, which extensions can be attached to inner walls of the container with their free ends.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: April 14, 2009
    Assignee: Dacro B.V.
    Inventors: Terence Dieter Siegers, Philip Jan Groen
  • Patent number: 7449324
    Abstract: The present invention provides an isolated mammalian negative strand RNA virus, metapneumovirus (MPV), within the sub-family Pneumoviridae, of the family Paramyxoviridae. The invention also provides isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. In particular the invention provides a mammalian MPV, subgroups and variants thereof. The invention relates to genomic nucleotide sequences of different isolates of mammalian metapneumoviruses, in particular human metapneumoviruses. The invention relates to the use of the sequence information of different isolates of mammalian metapneumoviruses for diagnostic and therapeutic methods. The present invention relates to nucleotide sequences encoding the genome of a metapneumovirus or a portion thereof, including both mammalian and avian metapneumovirus. The invention further encompasses chimeric or recombinant viruses encoded by said nucleotide sequences.
    Type: Grant
    Filed: February 21, 2003
    Date of Patent: November 11, 2008
    Assignees: ViroNovative BV, MedImmune, LLC
    Inventors: Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Cornelius De Jong, Jan Groen
  • Publication number: 20080102444
    Abstract: The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of human rhinovirus (HRV) in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved 5? untranslated region of the HRV genome. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention.
    Type: Application
    Filed: October 15, 2007
    Publication date: May 1, 2008
    Inventors: Ming Lee, Lilly Kong, Jan Groen