Patents by Inventor Jan H. Spaas

Jan H. Spaas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for isolation and purification of epithelial stem cells from skin
    Patent number: 9963676
    Abstract: The current invention concerns a method for obtaining a cellular composition comprising epithelial stem cells (EpSCs) from mammalian skin, whereby said composition comprises at least 90% of viable EpSCs, comprising the steps of: —obtaining a mammalian skin sample; —obtaining a cell suspension from said skin sample by performing at least one enzymatic dissociation step; and —culturing said cell suspension under low-attachment conditions. Preferably cellular composition comprises epithelial stem cells derived from the epidermal layer. In a second aspect, the current invention provides for a cellular composition obtained by the method according to the invention.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: May 8, 2018
    Assignee: Pell Cell Medicals NV
    Inventors: Sarah Y. Broeckx, Jan H. Spaas
  • METHOD FOR ISOLATION AND PURIFICATION OF EPITHELIAL STEM CELLS FROM SKIN
    Publication number: 20150232807
    Abstract: The current invention concerns a method for obtaining a cellular composition comprising epithelial stem cells (EpSCs) from mammalian skin, whereby said composition comprises at least 90% of viable EpSCs, comprising the steps of:—obtaining a mammalian skin sample;—obtaining a cell suspension from said skin sample by performing at least one enzymatic dissociation step; and—culturing said cell suspension under low-attachment conditions. Preferably cellular composition comprises epithelial stem cells derived from the epidermal layer. In a second aspect, the current invention provides for a cellular composition obtained by the method according to the invention.
    Type: Application
    Filed: August 20, 2013
    Publication date: August 20, 2015
    Inventors: Sarah Y. Broeckx, Jan H. Spaas