Patents by Inventor Jan HAVLIK

Jan HAVLIK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanodiamonds as artificial proteins for regulation of a cell signalling system
    Patent number: 11744855
    Abstract: Nanodiamonds having a positive ?-potential of at least 1 mV for use in sequestration of at least one FGF family member in organisms in vivo and in vitro. It has been found that nanodiamonds with a positive ?-potential show an extremely strong and selective binding to FGF family members, thus leading to their usability in the treatment of diseases related to aberrant FGF-FGFR signalling and/or interaction.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: September 5, 2023
    Assignees: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I, MASARYKOVA UNIVERZITA, FAKULTNI NEMOCNICE U SV, ANNY V BRNE
    Inventors: Petr Cigler, Lukas Balek, Jan Havlik, Pavel Krejci, Lukas Trantirek, Silvie Trantirkova
  • METHOD OF PRODUCTION OF IRRADIATED PARTICLES
    Publication number: 20210283568
    Abstract: The present invention relates to a process for ion irradiation of a particulate substrate containing the steps of embedding particulate substrate in a solid matrix having 10B atoms, and exposing the matrix obtained in the previous step to a neutron flux to give irradiated particulate substrate. The process is extremely effective and amenable to large scale and is particularly suitable for producing irradiated nanodiamonds and irradiated SiC particles.
    Type: Application
    Filed: July 8, 2019
    Publication date: September 16, 2021
    Applicants: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I., USTAV MAKROMOLEKULARNI CHEMIE AV CR, V. V. I.
    Inventors: Petr CIGLER, Jan HAVLIK, Martin HRUBY, Jan KUCKA
  • NANODIAMONDS AS ARTIFICIAL PROTEINS FOR REGULATION OF A CELL SIGNALLING SYSTEM
    Publication number: 20210015856
    Abstract: Nanodiamonds having a positive ?-potential of at least 1 mV for use in sequestration of at least one FGF family member in organisms in vivo and in vitro. It has been found that nanodiamonds with a positive ?-potential show an extremely strong and selective binding to FGF family members, thus leading to their usability in the treatment of diseases related to aberrant FGF-FGFR signalling and/or interaction.
    Type: Application
    Filed: March 26, 2019
    Publication date: January 21, 2021
    Applicants: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I., MASARYKOVA UNIVERZITA, FAKULTNI NEMOCNICE U SV. ANNY V BRNE
    Inventors: Petr CIGLER, Lukas BALEK, Jan HAVLIK, Pavel KREJCI, Lukas TRANTIREK, Silvie TRANTIRKOVA