Abstract: A novel methacrylic copolymer contains units derived from at least one alkyl methacrylate and methacrylamide. The units derived from methacrylamide are present in at least 34 wt.-%, based on the total weight of the methacrylic copolymer. A method can be used for preparing these novel methacylic copolymers. Pharmaceutical compositions, nutraceutical compositions, coated pharmaceutical or nutraceutical dosage forms, as well as nano- or microparticles can contain the methacrylic copolymer. The methacrylic copolymer can be used as a coating, as a carrier, and as a matrix for an amorphous solid dispersion.

Abstract: A dosage form contains a polymeric matrix, containing one or more polymer(s) and a biologically active ingredient. The polymeric matrix contains 10% by weight or more of the one or more polymer(s). The one or more polymer(s) are polymerized from a monomer mixture containing the monomers (a) 70 to 95% by weight of 2-ethylhexyl methacrylate (EHMA) and ethyl methacrylate (EMA), or 2-ethylhexyl methacrylate (EHMA) and methyl methacrylate (MMA); (b) 0 to 25% by weight of a C2 to C6 hydroxy-alkylester of acrylic acid or methacrylic acid; and (c) 2.5 to 20% by weight of a C2 to C8 alkyl ester of acrylic acid or of methacrylic acid with a quaternary cationic group in the alkyl group.

Abstract: A process can prepare a bio-resorbable polyester as a granulate or powder by bulk polymerization of one or more monomer(s). The process involves a) filling a monomer granulate, containing the one or more monomer(s), into a container; b) adding a polymerization catalyst and a chain length moderator on top of the monomer granulate; c) adding further monomer granulate on top; d) closing the container; e) carrying out a polymerization reaction in the closed container at a temperature in the range of 50° C. to 170° C., wherein a solid polymer in the form of a polymer block is formed; f) removing the polymer block from the container; and g) comminuting the polymer block to a granulate or powder; wherein the container is an unstirred container, wherein steps b) and c) are carried out once or are repeated, and wherein steps a) to e) are carried out under inert atmosphere.

Abstract: A polymer mixture includes 10 to 90 wt. % of polymer 1 and 10 to 90 wt. % of polymer 2, the total being 100 wt. %. Polymer 1 is polymerized from (a1) 70-95 wt. % of C1-C12 alkylester of (meth)acrylic acid, and (b1) 5-30% wt. % of C2-C8 alkyl ester of (meth)acrylic acid with a quaternary cationic group in the alkyl group. Polymer 2 is polymerized from (a2) 70-95 wt. % of C1-C12 alkylester of (meth)acrylic acid, and (c2) 5-30 wt. % of C2-C6 hydroxy-alkylester of (meth)acrylic acid. Monomers (a1) and (b1) add up to 98-100 wt. %, and most preferred to 100 wt. %. Monomers (a2) and (c2) add up to 98-100 wt. %, most preferred to 100 wt %.

Abstract: A polymer is polymerized from a monomer mixture containing (a) 70 to 95% by weight of 2-ethylhexyl methacrylate (EHMA) and ethyl methacrylate (EMA) or 2-ethylhexyl methacrylate (EHMA) and methyl methacrylate (MMA), (b) 2.5 to 25% by weight of one or more C2 to C6 hydroxy-alkyl esters of acrylic acid or methacrylic acid, (c) 2.5 to 15% by weight of one or more C2 to C8 alkyl esters of acrylic acid or of methacrylic acid with a quaternary cationic group in the alkyl group. The polymer is useful for preparing a dosage form with a sustained release profile and resistance against the influence of ethanol.

Abstract: The invention relates to a coating composition suitable for the coating of a pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerization process, wherein either the core of the core/shell polymer composition is formed by a water-insoluble, not cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer or vice versa.

Abstract: The invention discloses a gastric resistant pharmaceutical or nutraceutical composition, comprising a core, comprising a pharmaceutical or nutraceutical active ingredient and a gastric resistant coating layer onto the core, wherein the gastric resistant coating layer comprises at least 30% by weight of a (meth)acrylate copolymer comprising polymerized units of 10 to 40% by weight of acrylic or methacrylic acid, 10 to 80% by weight of a C4- to C18-alkyl ester of acrylic or methacrylic acid and optionally 0 to 60% by weight of another vinylic monomer, whereby the release of the pharmaceutical or nutraceutical active ingredient is not more than 10% under in-vitro conditions at pH 1.2 after 2 hours in medium according to USP with and without the addition of 20% (v/v) ethanol.

Abstract: The invention relates to a coating composition suitable for the coating of pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerization process, wherein the core of the core/shell polymer composition is formed by a water-insoluble, cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer.

Abstract: The present invention relates to dispersion-based paints or varnishes, more particularly for use as coating material (architectural paint), which have a low pigment volume concentration (PVC), lower than the critical pigment volume concentration (CPVC). The varnishes have high water vapour permeability and low water absorption. They are notable for good weathering resistance and resistance to wet abrasion, shade stability and chalking stability, and a variable, adjustable gloss.

Abstract: The invention relates to plastisols which even without the addition of adhesion promoters exhibit high adhesion to metallic and cathodically deposition-coated substrates.

Abstract: The invention relates to pulverulent core/shell polymers for the preparation of a plastisol, which have surprisingly low water absorption. The invention further relates to the plastisol pastes which are prepared from these polymers and likewise have low water absorption and additionally possess good storage stability, good mechanical properties and good plasticizer compatibility. The core/shell polymers consist of latex particles having a primary particle size of at least 250 nm, the core consisting of methyl methacrylate, (meth)acrylic esters with C2 to C8 or aromatic alcohol radicals and optionally further monomers, and the shells(s) comprising, in addition to these components, also amides of (meth)acrylic acid and/or amine-substituted alkyl esters of (meth)acrylic acid.

Abstract: The invention discloses a gastric resistant pharmaceutical or nutraceutical composition, comprising a core, comprising a pharmaceutical or nutraceutical active ingredient and a gastric resistant coating layer onto the core, wherein the gastric resistant coating layer comprises at least 30% by weight of a (meth)acrylate copolymer comprising polymerized units of 10 to 40% by weight of acrylic or methacrylic acid, 10 to 80% by weight of a C4- to C18-alkyl ester of acrylic or methacrylic acid and optionally 0 to 60% by weight of another vinylic monomer, whereby the release of the pharmaceutical or nutraceutical active ingredient is not more than 10% under in-vitro conditions at pH 1.2 after 2 hours in medium according to USP with and without the addition of 20% (v/v) ethanol.

Abstract: The invention relates to a coating composition suitable for the coating of a pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerisation process, wherein either the core of the core/shell polymer composition is formed by a water-insoluble, not cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer or vice versa.

Abstract: The invention relates to a coating composition suitable for the coating of pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerisation process, wherein the core of the core/shell polymer composition is formed by a water-insoluble, cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer.

Abstract: The invention relates to hybrid materials comprising polymers which envelop nanoscale, superparamagnetic, ferromagnetic, ferrimagnetic or paramagnetic powders, to a process for producing these materials and to their use.

Abstract: The present invention relates to the use of different-sized polymeric microparticles in hydraulically setting building material mixtures for the purpose of enhancing their frost resistance and cyclical freeze/thaw durability.

Abstract: The invention relates to a method of bonding different materials of construction using hybrid materials comprising nanoscale, superparamagnetic, ferromagnetic, ferrimagnetic or paramagnetic powders enveloped or in part not enveloped by poly(meth)acrylates, and to their use.

Abstract: The invention relates to plastisols which even without the addition of adhesion promoters exhibit high adhesion to metallic and cathodically deposition-coated substrates.

Abstract: The invention relates to a process for preparing binders for plastisols that ensures high and consistent product quality over a multiplicity of batches. The binders obtained from this process allow the formulation of plastisols which possess improved stability on storage and, after gelling, improved mechanical properties.

Abstract: The invention relates to plastisol systems with improved adhesion and with lower water absorption.