Patents by Inventor Jan Holgersson

Jan Holgersson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Inhibiting Viral Adhesion
    Publication number: 20140256019
    Abstract: The present invention provides compositions and methods for treating or preventing viral infections.
    Type: Application
    Filed: March 4, 2014
    Publication date: September 11, 2014
    Applicant: RECOPHARMA AB
    Inventor: Jan Holgersson
  • Blood group antigens of different types for diagnostic and therapeutic applications
    Patent number: 8404456
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection and blood typing.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: March 26, 2013
    Assignee: AbSorber AB
    Inventors: Jan Holgersson, Jining Liu, Linda Lindberg, Per Grufman
  • Tear Substitutes
    Publication number: 20120165272
    Abstract: The invention features ophthalmic formulations of mucin polypeptides to treat or prevent dry eye.
    Type: Application
    Filed: December 21, 2011
    Publication date: June 28, 2012
    Applicant: Recopharma AB
    Inventors: Jan Holgersson, Anki Nilsson, Nathalie Chatzissavidou, Tomas Johansson
  • Mucin Fusion Polypeptide Vaccines, Compositions And Methods Of Use Thereof
    Publication number: 20120034220
    Abstract: The present invention provides compositions and methods for augmenting vaccine immunogenicity using mucin-immunoglobulin fusion proteins.
    Type: Application
    Filed: October 11, 2011
    Publication date: February 9, 2012
    Applicant: Recopharma AB
    Inventor: Jan Holgersson
  • Compositions And Methods For Inhibiting Viral Adhesion
    Publication number: 20120020969
    Abstract: The present invention provides compositions and methods for treating or preventing viral infections.
    Type: Application
    Filed: September 29, 2011
    Publication date: January 26, 2012
    Applicant: Recopharma AB
    Inventor: Jan Holgersson
  • BLOOD GROUP ANTIGENS OF DIFFERENT TYPES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
    Publication number: 20110287556
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection and blood typing.
    Type: Application
    Filed: February 28, 2011
    Publication date: November 24, 2011
    Applicant: AbSorber AB
    Inventors: Jan Holgersson, Jining Liu, Linda Lindberg, Per Grufman
  • Mucin fusion polypeptide vaccines, compositions and methods of use thereof
    Patent number: 8034351
    Abstract: The present invention provides compositions and methods for augmenting vaccine immunogenicity using mucin-immunoglobulin fusion proteins.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: October 11, 2011
    Assignee: Recopharma AB
    Inventor: Jan Holgersson
  • Immortalized Human Fetal Liver Cells
    Publication number: 20110136101
    Abstract: The present invention provides immortalized fetal liver cells that express the oncogene Simian virus (SV 40) large T-antigen and specific hepatocyte markers and a method for producing same.
    Type: Application
    Filed: December 6, 2010
    Publication date: June 9, 2011
    Inventors: Jan Holgersson, Suchitra Holgersson, Setara Begum, Marika I. Kleman, Monica Ek
  • Blood group antigens of different types for diagnostic and therapeutic applications
    Patent number: 7897328
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection and blood typing.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: March 1, 2011
    Assignee: AbSorber AB
    Inventors: Jan Holgersson, Jining Liu, Linda Lindberg, Per Grufman
  • Compositions and methods for inhibiting adhesion and infection
    Patent number: 7658919
    Abstract: The present invention provides compositions and methods for treating or preventing bacterial infections. Also provide by the invention are genetically modified cell expressing Lewisb carbohydrate epitope.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: February 9, 2010
    Assignee: Recopharma AB
    Inventors: Jan Holgersson, Jining Liu, Anki Gustafsson, Jonas Lofling
  • Fusion proteins and methods of producing same
    Patent number: 7638323
    Abstract: The present invention provides compositions and methods for treating or preventing hyperacute rejection.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: December 29, 2009
    Assignee: Recopharma AB
    Inventors: Jan Holgersson, Jining Liu, Anki Gustafsson
  • ANTIGENIC FUSION PROTEIN CARRYING GAL ALPHA1,3GAL EPITOPES
    Publication number: 20090286963
    Abstract: The present invention relates to an antigenic fusionprotein, which carries multiple Gal?1,3Gal epitopes. The fusion protein according to the invention may also be comprised of a heavily glycosylated mucin part, which mediates binding to selectins, such as PSGL-1, and a part, which exhibits immunoglobulin properties, such as the Fc part of IgG. The fusionprotein according to the invention is preferably used as an absorber to prevent a hyperacute rejection of a xenotransplant, such as a pig tissue or organ transplanted into a human patient. In addition, the invention relates to a method for the prevention of a hyperacute rejection reaction in a patient who is to receive a xenotransplant.
    Type: Application
    Filed: July 22, 2009
    Publication date: November 19, 2009
    Applicant: Recopharma AB
    Inventors: Jan Holgersson, Jining Liu
  • COMPOSITIONS AND METHODS FOR INHIBITING TOXIN A FROM CLOSTRIDIUM DIFFICILE
    Publication number: 20090280134
    Abstract: The present invention provides compositions and methods for treating or preventing infection by Toxin A producing bacteria.
    Type: Application
    Filed: May 11, 2009
    Publication date: November 12, 2009
    Applicant: RECOPHARMA AB
    Inventors: Jan Holgersson, Anki Gustafsson
  • COMPOSITIONS AND METHODS FOR INHIBITING SHIGA TOXIN AND SHIGA-LIKE TOXIN
    Publication number: 20090280104
    Abstract: The present invention provides compositions and methods for treating or preventing infection by shiga toxin producing bacteria.
    Type: Application
    Filed: May 11, 2009
    Publication date: November 12, 2009
    Applicant: RECOPHARMA AB
    Inventors: Jan Holgersson, Anki Gustafsson
  • Production of proteins carrying oligomannose or human-like glycans in yeast and methods of use thereof
    Publication number: 20090181041
    Abstract: Cell lines having genetically modified glycosylation pathways that allow them to carry out a sequence of enzymatic reactions, which mimic the processing of glycoproteins in humans, have been developed. Recombinant proteins expressed in these engineered hosts yield glycoproteins more similar, if not substantially identical, to their human counterparts. The lower eukaryotes, which ordinarily produce high-mannose containing N-glycans, including unicellular and multicellular fungi are modified to produce O-glycans or other structures along human glycosylation pathways.
    Type: Application
    Filed: September 18, 2008
    Publication date: July 16, 2009
    Inventors: Jan Holgersson, Anki Gustafsson, Magnus Sjoholm, Ulrika Rova
  • Blood group antigen fusion polypeptides and methods of use thereof
    Publication number: 20080319173
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection.
    Type: Application
    Filed: January 30, 2008
    Publication date: December 25, 2008
    Inventors: Jonas Lofling, Jan Holgersson
  • Compositions and methods for inhibiting microbial adhesion
    Publication number: 20080096806
    Abstract: The present invention provides compositions and methods for treating or preventing microbial infections.
    Type: Application
    Filed: November 5, 2007
    Publication date: April 24, 2008
    Inventors: Jan Holgersson, Jonas Lofling
  • Blood group antigen fusion polypeptides and methods of use thereof
    Patent number: 7355017
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: April 8, 2008
    Assignee: Absorber AB
    Inventors: Jonas Lofling, Jan Holgersson
  • Blood Group Antigens of Different Types for Diagnostic and Therapeutic Applications
    Publication number: 20070224652
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection and blood typing.
    Type: Application
    Filed: March 23, 2007
    Publication date: September 27, 2007
    Inventors: Jan Holgersson, Jining Liu, Linda Bjornstrom, Per Grufman
  • Production of Proteins Carrying Oligomannose or Human-Like Glycans in Yeast and Methods of Use Thereof
    Publication number: 20070184063
    Abstract: Cell lines having genetically modified glycosylation pathways that allow them to carry out a sequence of enzymatic reactions, which mimic the processing of glycoproteins in humans, have been developed. Recombinant proteins expressed in these engineered hosts yield glycoproteins more similar, if not substantially identical, to their human counterparts. The lower eukaryotes, which ordinarily produce high-mannose containing N-glycans, including unicellular and multicellular fungi are modified to produce O-glycans or other structures along human glycosylation pathways.
    Type: Application
    Filed: January 23, 2007
    Publication date: August 9, 2007
    Inventors: Jan Holgersson, Anki Gustafsson