Patents by Inventor Jan Holinsky

Jan Holinsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8715952
    Abstract: In general, the present invention provides a reliable assay for the quantitative determination of p-aminophenol in an aqueous sample. More particularly, the present invention provides a rapid enzyme-based assay for the quantitative determination of acetaminophen in a sample. The assay employs a xylenol chromophore and a catalyst that is preferably a weak oxidizer. The assay provides reliable results in the presence or absence of N-acetylcystiene (NAC) and can therefore be used to monitor acetaminophen levels during NAC treatment. Methods and kits for determining acetaminophen concentration in an aqueous sample are also provided.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: May 6, 2014
    Assignee: Sekisui Diagnostics LLC
    Inventors: Michael Bulger, Jan Holinsky
  • Publication number: 20120301969
    Abstract: In general, the present invention provides a reliable assay for the quantitative determination of p-aminophenol in an aqueous sample. More particularly, the present invention provides a rapid enzyme-based assay for the quantitative determination of acetaminophen in a sample. The assay employs a xylenol chromophore and a catalyst that is preferably a weak oxidizer. The assay provides reliable results in the presence or absence of N-acetylcystiene (NAC) and can therefore be used to monitor acetaminophen levels during NAC treatment. Methods and kits for determining acetaminophen concentration in an aqueous sample are also provided.
    Type: Application
    Filed: July 9, 2012
    Publication date: November 29, 2012
    Applicant: Sekisui Diagnostics, LLC
    Inventors: Michael Bulger, Jan Holinsky
  • Patent number: 8236519
    Abstract: In general, the present invention provides a reliable assay for the quantitative determination of p-aminophenol in an aqueous sample. More particularly, the present invention provides a rapid enzyme-based assay for the quantitative determination of acetaminophen in a sample. The assay employs a xylenol chromophore and a catalyst that is preferably a weak oxidizer. The assay provides reliable results in the presence or absence of N-acetylcystiene (NAC) and can therefore be used to monitor acetaminophen levels during NAC treatment. Methods and kits for determining acetaminophen concentration in an aqueous sample are also provided.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: August 7, 2012
    Assignee: Sekisui Diagnostics, LLC
    Inventors: Michael Bulger, Jan Holinsky
  • Publication number: 20090269792
    Abstract: In general, the present invention provides a reliable assay for the quantitative determination of p-aminophenol in an aqueous sample. More particularly, the present invention provides a rapid enzyme-based assay for the quantitative determination of acetaminophen in a sample. The assay employs a xylenol chromophore and a catalyst that is preferably a weak oxidizer. The assay provides reliable results in the presence or absence of N-acetylcystiene (NAC) and can therefore be used to monitor acetaminophen levels during NAC treatment. Methods and kits for determining acetaminophen concentration in an aqueous sample are also provided.
    Type: Application
    Filed: April 17, 2009
    Publication date: October 29, 2009
    Inventors: Michael Bulger, Jan Holinsky