Patents by Inventor Jan-Ingmar Flock

Jan-Ingmar Flock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fibrinogen binding protein originating from coagulase-negative staphylococcus
    Publication number: 20040209326
    Abstract: A new fibrinogen binding protein or polypeptide originating from coagulase negative staphylococci, biotechnological methods for producing the protein or polypeptide having fibrinogen binding activity and a recombinant DNA molecule coding for the protein (or fragments thereof), and micro-organisms (including viruses) containing this recombinant DNA molecule. The present invention further comprises the therapeutic and diagnostic use of the protein and/or DNA, e.g., a diagnostic kit for determining the presence and/or type of coagulase negative staphylococci and a vaccine composition, comprising the protein or DNA.
    Type: Application
    Filed: March 23, 2004
    Publication date: October 21, 2004
    Inventors: Bengt Guss, Martin Nilsson, Lars Frykberg, Jan-Ingmar Flock, Martin Lindberg
  • Fibrinogen binding protein originating from coagulase-negative staphylococcus
    Patent number: 6733758
    Abstract: A new fibrinogen binding protein or polypeptide originating from coagulase negative staphylococci, biotechnological methods for producing the protein or polypeptide having fibrinogen binding activity and a recombinant DNA molecule coding for the protein (or fragments thereof), and micro-organisms (including viruses) containing this recombinant DNA molecule. The present invention further comprises the therapeutic and diagnostic use of the protein and/or DNA, e.g., a diagnostic kit for determining the presence and/or type of coagulase negative staphylococci and a vaccine composition, comprising the protein or DNA.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: May 11, 2004
    Inventors: Bengt Guss, Martin Nilsson, Lars Frykberg, Jan-Ingmar Flock, Martin Lindberg
  • Specificity exchangers that redirect antibodies to a pathogen
    Publication number: 20030225251
    Abstract: Specificity exchangers and methods of making and using specificity exchangers are disclosed. Specificity exchangers are useful for preventing and treating human diseases including cancer and those resulting from pathogens such as bacteria, yeast, parasites, fungus, viruses, and the like. More specifically, specificity exchangers can redirect existing antibodies in a subject to pathogens and cancer cells.
    Type: Application
    Filed: February 21, 2003
    Publication date: December 4, 2003
    Inventors: Matti Sallberg, Jan-Ingmar Flock
  • Use of a composition
    Publication number: 20030105020
    Abstract: A method of treatment of a mammal suffering from an inflammatory condition by administration of an anti-inflammatory drug comprising a protein or a peptide fraction of said protein comprising at least one repeating unit thereof, said protein being selected from a group of proteins designated Eap (Extracellular adherence protein). The inflammatory condition may be a non-bacterial or bacterial inflammation.
    Type: Application
    Filed: November 18, 2002
    Publication date: June 5, 2003
    Inventors: Jan-Ingmar Flock, Triantafyllos Chavakis, Mathias Herrmann, Klaus T. Preissner
  • Fibrinogen binding protein
    Publication number: 20020173462
    Abstract: The present invention relates to fibrinogen binding proteins, and agents comprising those proteins, for use in immunization, for therapeutics and for diagnostic purposes.
    Type: Application
    Filed: August 27, 2001
    Publication date: November 21, 2002
    Inventors: Maria K. Boden Wastfelt, Jan-Ingmar Flock
  • Methods of immunization by administering fibrinogen binding protein or fragments thereof
    Patent number: 6299879
    Abstract: The present invention provides a method for immunizing a mammal against Staphylococcus infection comprising administering to that mammal a protein or fragment thereof comprising the amino acid sequence: (SEQ ID NO:8) SEGYGPREKK PVSINHNIVE YNDGTFKYQS RPKFNSTPKY IKFKHDYNIL EFNDGTFEYG ARPQFNKPAA KTDATIKKEQ KLIQAQNLVR EFEKTHTVSA HRKAQKAVNL VSFEYKVKKM VLQERIDNVL KQGLVR, or a fragment thereof retaining that portion of the sequence responsible for fibrinogen binding activity.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: October 9, 2001
    Assignee: Alfa Laval Agri International Aktiebolag
    Inventors: Maria K. Bodén Wästfält, Jan-Ingmar Flock
  • Method and means for producing an immunoglobulin-binding protein
    Patent number: 5976861
    Abstract: Method for producing a protein having the same IgG specificity as protein G from group G Streptococci, strain G148. The invention also relates to a recombinant DNA molecule coding for said protein, and to microorganisms containing this recombinant DNA molecule. The invention also relates to a recombinant DNA molecule coding for a protein having the IgG binding specificity of both protein G and protein A.
    Type: Grant
    Filed: May 16, 1989
    Date of Patent: November 2, 1999
    Assignee: Pharmacia Biotech Aktiebolag
    Inventors: Bengt Mikael Guss, Jan Ingmar Flock, Martin Kjell Lindberg, Mathias Carl Erik Uhlen
  • Method and means for producing an immunoglobulin-binding protein
    Patent number: 5756670
    Abstract: Method for producing a protein having the same IgG specificity as protein G from group G Streptococci, strain G148. The invention also relates to a recombinant DNA molecule coding for said protein, and to microorganisms containing this recombinant DNA molecule. The invention also relates to a recombinant DNA molecule coding for a protein having the IgG binding specificity of both protein G and protein A.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 26, 1998
    Assignee: Pharmacia Biotech Aktiebolag
    Inventors: Bengt Mikael Guss, Jan Ingmar Flock, Martin Kjell Lindberg, Mathias Carl Erik Uhlen