Patents by Inventor Jan J. Lewandowski
Jan J. Lewandowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9125969Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.Type: GrantFiled: March 16, 2012Date of Patent: September 8, 2015Assignee: NANOMIMETICS, INC.Inventors: Jan J. Lewandowski, Yubiao Liu, Roger Marchant, Tianhong Zhang, Yongxing Qiu, Mark A. Ruegsegger
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Patent number: 8945664Abstract: A biomimetic surfactant polymer modified with various crosslinking embodiments is described. The crosslinking embodiments provide a biomimetic surfactant coating that is designed to resist cracking, scratching, spalling and chemical dissolution. The crosslinking embodiments comprise the use of various hydrophilic and hydrophobic functional groups. The modified biomimetic surfactant adheres to different substrate surfaces, particularly the surfaces of medical devices.Type: GrantFiled: October 28, 2011Date of Patent: February 3, 2015Assignee: Greatbatch Ltd.Inventors: Jan J. Lewandowski, Yubiao Liu
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Patent number: 8765113Abstract: A comb-like surfactant polymer for changing the surface properties of biomaterials is described. The surfactant polymer comprises a polymeric backbone of repeating monomeric units having functional groups for chemically attaching to side chains, a plurality of hydrophobic side chains attached to the backbone via the functional groups and a plurality of hydrophilic side chains chemically attached via functional groups to the polymeric backbone. The hydrophilic side chains providing anti-thrombogenic properties to the surfactant. An antimicrobial agent selectively attached to some hydrophilic side chains thereby providing additional antimicrobial properties to the surfactant. The surfactant polymer may be applied to the surface of medical devices to reduce the surfaces thrombogenicity and decrease the number of microorganisms on the surface.Type: GrantFiled: June 27, 2012Date of Patent: July 1, 2014Assignee: Greatbatch Ltd.Inventors: Jan J. Lewandowski, Yubaio Liu
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Publication number: 20120328556Abstract: A comb-like surfactant polymer for changing the surface properties of biomaterials is described. The surfactant polymer comprises a polymeric backbone of repeating monomeric units having functional groups for chemically attaching to side chains, a plurality of hydrophobic side chains attached to the backbone via the functional groups and a plurality of hydrophilic side chains chemically attached via functional groups to the polymeric backbone. The hydrophilic side chains providing anti-thrombogenic properties to the surfactant. An antimicrobial agent selectively attached to some hydrophilic side chains thereby providing additional antimicrobial properties to the surfactant. The surfactant polymer may be applied to the surface of medical devices to reduce the surfaces thrombogenicity and decrease the number of microorganisms on the surface.Type: ApplicationFiled: June 27, 2012Publication date: December 27, 2012Applicant: Greatbatch Ltd.Inventors: Jan J. Lewandowski, Yubiao Liu
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Publication number: 20120245288Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.Type: ApplicationFiled: March 16, 2012Publication date: September 27, 2012Applicant: NANOMIMETICS, INC.Inventors: Jan J. LEWANDOWSKI, Yubiao LIU
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Publication number: 20080262614Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.Type: ApplicationFiled: April 4, 2008Publication date: October 23, 2008Applicant: NANOMIMETICS, INC.Inventors: Roger E. MARCHANT, Jan J. LEWANDOWSKI, Yubiao LIU
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Publication number: 20070261494Abstract: Detection apparatus can include a positioning device with a wall including a substantially conical inner surface and a detection device configured to send and receive signals and move along the conical inner surface. Detection apparatus are also provided that comprise a positioning device and an end portion with an image port, a light device, and a detection device configured to send and receive signals. Ultrasonic transducer devices are also provided with a transducer material layer, a contact plating layer including a convex portion with an array of transducer elements, an acoustic matching layer, and a top plating layer.Type: ApplicationFiled: April 3, 2007Publication date: November 15, 2007Applicant: BIOMEC, INC.Inventors: William R. Fuller, Daniel N. Kelsch, Jan J. Lewandowski, Grazyna Palczewska, Alexander K. Smith
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Publication number: 20030209450Abstract: An electrochemical sensor (A, A′) is specific for the detection of peroxyacetic acid in a solution which also contains hydrogen peroxide. A potential is applied between a reference electrode (120, 120′) and a working electrode (118, 118′). A read voltage (FIG. 7) is selectively pulsed across a counter electrode (122, 122′) and the working electrode. The current flowing between the working electrode and the counter electrode is dependent on the peroxyacetic acid concentration in the solution (FIG. 6). By careful selection of the read voltage, the contribution of hydrogen peroxide to the current flow is virtually negligible. The sensor effectively measures peroxyacetic acid concentrations in the range generally employed in sterilization and disinfection baths (100-3000 ppm.).Type: ApplicationFiled: April 1, 2003Publication date: November 13, 2003Inventors: Iain F. McVey, Brian J. DeSantis, Jan J. Lewandowski, Karen L. Thomas, Brian E. Schindly
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Patent number: 6592730Abstract: An electrochemical analysis system includes a chamber (34) that defines a fluid receiving reservoir therein. A working electrode (40), a reference electrode (42), and a counter electrode (44) is mounted to the chamber. An electrochemical analysis circuit (38) applies appropriate voltages to the electrodes and reads appropriate currents from the electrodes to provide an indication of the peroxyacetic acid concentration in a sample. The working electrode includes a glassy carbon rod (60) which is surrounded by a compressible polymeric sleeve (64) and a metal sleeve (66). One end of the metal sleeve is swaged (68) to form a fluid tight compression seal with the insulating sleeve and the glassy carbon rod. An electrically conductive thermal extension joint between the glassy carbon rod and an electrically conductive rod (70) includes a bore (72) in the conductive rod in which the glassy carbon rod is slidably received and a compressed spring (74) in the bore.Type: GrantFiled: February 7, 2000Date of Patent: July 15, 2003Assignee: Steris Inc.Inventors: Daniel N. Kelsch, Iain F. McVey, Jan J. Lewandowski
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Patent number: 6558529Abstract: An electrochemical sensor (A, A′) is specific for the detection of peroxyacetic acid in a solution which also contains hydrogen peroxide. A potential is applied between a reference electrode (120, 120′) and a working electrode (118, 118′). A read voltage (FIG. 7) is selectively pulsed across a counter electrode (122, 122′) and the working electrode. The current flowing between the working electrode and the counter electrode is dependent on the peroxyacetic acid concentration in the solution (FIG. 6). By careful selection of the read voltage, the contribution of hydrogen peroxide to the current flow is virtually negligible. The sensor effectively measures peroxyacetic acid concentrations in the range generally employed in sterilization and disinfection baths (100-3000 ppm.).Type: GrantFiled: February 7, 2000Date of Patent: May 6, 2003Assignee: Steris Inc.Inventors: Iain F. McVey, Brian J. DeSantis, Jan J. Lewandowski, Karen L. Thomas, Brian E. Schindly
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Patent number: 5304203Abstract: Tissue extracting forceps are disclosed which have been designed for use in laparoscopic surgery. The forceps firmly grasp tissue or organs which are to be moved or removed during the procedure. The grasping members of the forceps are aligned such that fragmentation damage to the grasped tissue is minimized. The mechanical layout of the forceps allows the user to manipulate the working end for a distance, so that the user's fingers do not get in the way of the surgical procedure. The working end of the forceps is adaptable to be used with grasping members of different shapes, or with disposable cutting instruments. Any of these working ends may be incorporated in the same overall mechanical design.Type: GrantFiled: October 20, 1992Date of Patent: April 19, 1994Assignee: NuMed Technologies, Inc.Inventors: Amin El-Mallawany, Jan J. Lewandowski
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Patent number: D388874Type: GrantFiled: December 23, 1996Date of Patent: January 6, 1998Assignee: ViAtro, Corp.Inventors: Jan J. Lewandowski, Nick A. Deeter
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Patent number: D389964Type: GrantFiled: December 20, 1996Date of Patent: January 27, 1998Assignee: ViAtro, Corp.Inventors: Jan J. Lewandowski, Nick A. Deeter, John A. Engelhardt
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Patent number: D390668Type: GrantFiled: December 23, 1996Date of Patent: February 10, 1998Assignee: ViAtro, Corp.Inventors: Jan J. Lewandowski, Nick A. Deeter