Patents by Inventor Jan Jiricek

Jan Jiricek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5,6-FUSED-BICYCLIC COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES
    Publication number: 20220324863
    Abstract: The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: May 13, 2022
    Publication date: October 13, 2022
    Inventors: Jan Jiricek, Isabelle K. Lerario, Fang Liang, Xiaodong Liu, Valentina Molteni, Advait Suresh Nagle, Shuyi Pearly NG, Maxim Ratnikov, Jeffrey M. Smith, Yongping Xie
  • 5,6-fused-bicyclic compounds and compositions for the treatment of parasitic diseases
    Patent number: 11384078
    Abstract: The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: July 12, 2022
    Assignee: Novartis AG
    Inventors: Jan Jiricek, Isabelle K. Lerario, Fang Liang, Xiaodong Liu, Valentina Molteni, Advait Suresh Nagle, Shuyi Pearly Ng, Maxim Ratnikov, Jeffrey M. Smith, Yongping Xie
  • CYANOTRIAZOLE COMPOUNDS AND USES THEREOF
    Publication number: 20220106296
    Abstract: The present invention provides a compound of Formula (I), or a pharmaceutically acceptable salt thereof: (I) wherein R1, R2, R3, and R4 are as defined herein. The present invention further provides therapeutic uses of these compounds, for example against human African typanosomiasis; pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.
    Type: Application
    Filed: June 18, 2019
    Publication date: April 7, 2022
    Inventors: Jan Jiricek, Shuyi Pearly Ng, Srinivasa P S Rao
  • INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF
    Publication number: 20210032202
    Abstract: A compound of Formula (1) is provided that has been shown to be useful for treating a disease, disorder or syndrome that is mediated by the transportation of essential molecules in the mmpL3 pathway: wherein R1, R2, R3, R4, R5 and R6 are as defined herein.
    Type: Application
    Filed: June 12, 2020
    Publication date: February 4, 2021
    Inventors: Jan JIRICEK, Ravinder Reddy KONDREDDI, Paul William SMITH
  • 5,6-FUSED-BICYCLIC COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES
    Publication number: 20200109142
    Abstract: The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: May 29, 2018
    Publication date: April 9, 2020
    Inventors: Jan Jiricek, Isabelle K. Lerario, Fang Liang, Xiaodong Liu, Valentina Molteni, Advait Suresh Nagle, Pearly NG, Maxim Ratnikov, Jeffrey M. Smith, Yongping Xie
  • INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF
    Publication number: 20160355477
    Abstract: A compound of Formula (I) is provided that has been shown to be useful for treating a disease, disorder or syndrome that is mediated by the transportation of essential molecules in the mmpL3 pathway: wherein R1, R2, R3, R4, R5 and R6 are as defined herein.
    Type: Application
    Filed: August 19, 2016
    Publication date: December 8, 2016
    Applicant: NOVARTIS AG
    Inventors: Jan Jiricek, Ravinder Reddy Kondreddi, Paul William Smith
  • Indole carboxamide derivatives and uses thereof
    Patent number: 9447039
    Abstract: A compound of Formula (I) is provided that has been shown to be useful for treating a disease, disorder or syndrome that is mediated by the transportation of essential molecules in the mmpL3 pathway: wherein R1, R2, R3, R4, R5 and R6 are as defined herein.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: September 20, 2016
    Assignee: Novartis AG
    Inventors: Jan Jiricek, Ravinder Reddy Kondreddi, Paul William Smith
  • INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF
    Publication number: 20150175539
    Abstract: A compound of Formula (I) is provided that has been shown to be useful for treating a disease, disorder or syndrome that is mediated by the transportation of essential molecules in the mmpL3 pathway: wherein R1, R2, R3, R4, R5 and R6 are as defined herein.
    Type: Application
    Filed: September 5, 2013
    Publication date: June 25, 2015
    Applicant: Novartis AG
    Inventors: Jan Jiricek, Ravinder Reddy Kondreddi, Paul William Smith
  • Nitroimidazole Compounds
    Publication number: 20080275035
    Abstract: The present invention relates to certain nitroimidazole compounds, which have interesting pharmaceutical properties. In particular, the compounds are useful in the treatment and/or prevention of infections such as those caused by Mycobacterium tuberculosis, Trypanosoma cruzi or Leishmania donovani. The invention also relates to pharmaceutical compositions containing the compounds, as well as processes for their preparation.
    Type: Application
    Filed: December 22, 2006
    Publication date: November 6, 2008
    Inventors: Jan Jiricek, Sejal Patel, Thomas Hugo Keller, Clifton E. Barry, Cynthia S. Dowd