Abstract: The present invention relates to the field of molecular biochemistry and medicine, and in particular to ligands comprising modified amino acid residues, targeting the amyloid-? peptide associated with Alzheimer's disease for prevention of aggregation, neurotoxicity and use thereof as drugs for treatment of Alzheimer's disease.

Abstract: A method of small cell discovery in a wireless network deployment using a Channel State Information Reference System (CSI-RS) is proposed. First, a wireless communication system allocates pairs of resource elements in each resource block of a subframe to a CSI-RS configuration. A first of two orthogonal cover codes is applied to the first CSI-RS. The CSI-RS is transmitted by a small cell to a user equipment (UE). The UE utilizes the CSI-RS to perform small cell discovery and measurement of the small cell.

Abstract: The present document discloses an apparatus for receiving Physical Uplink Control Channel (PUCCH) in Long Term Evolution (LTE) system, comprising: blocks of system FFT performing system FFT on data from a plurality of antennas, blocks of PUCCH RB processing units receiving the allocated logic resource index table and the local base sequence and output of the blocks of system FFT, and generating DMRS despread outputs and data values; a block of SR detection for receiving the data values and the DMRS despread outputs, and for generating SR detection results; blocks of user data extraction receiving data values and DMRS despread outputs, and performing user data extraction; blocks of PUCCH user processing units receiving an orthogonal sequence index, the data values and an output from blocks of user extraction, and generating a ACK/NAK/CQI signal for a concerned UE.

Abstract: A new approach to generating a probing signal by a cell in a heterogeneous network (HetNet) deployment is proposed. A small cell in the HetNet may be switched off by a base station when the small cell is not needed. The small cell is configured to alternate between an off-state and on-state. The small cell maintains the on-state for a predetermined probing period and maintains the off-state for a predetermined off period. The small cell may switch between the on-state and the off-state periodically. The small cell may be activated during a predetermined off period to transmit data to a user device.

Abstract: A gyratory crusher includes a spider supported at a top shell, the spider having a pair of spider arms protected by respective arm shields. The shields are mounted and dismounted at the respective arms via a locking flange and notch and lug arrangement to avoid attachment by welding or attachment bolts.

Abstract: The proposed approach comtemplates systems and methods configured to utilize a modified reference signal to facilitate efficient discovery of as many cells as possible within one channel state information reference signal (CSI-RS) sub-frame while maintaining certain detection and measurement performance. The proposed approach is configured to unambiguously discover at least the number of anticipated small cells within one cluster and to further identify all small cells within the coverage area of a base station/macro cell. In some embodiments, frequency multiplexing is utilized to allow different cells to transmit their discovery signals on different physical resource blocks (PRBs) rather than one cell using every PRB over the entire system bandwidth.

Abstract: The present invention provides a family of non-naturally occurring polypeptides having cholesterol efflux activity that parallels that of full-length apolipoproteins (e.g., Apo AI and Apo E), and having high selectivity for ABCA1 that parallels that of full-length apolipoproteins. Further, the peptides of the invention have little or no toxicity when administered at therapeutic and higher doses. The invention also provides compositions comprising such polypeptides, methods of identifying, screening and synthesizing such polypeptides, and methods of treating, preventing or diagnosing diseases and disorders associated with dyslipidemia, hypercholesterolemia and inflammation.

Abstract: The proposed approach contemplates systems and methods configured to transmit signals irregularly (sparsely) over a mobile communication network (carrier) in which reception gaps apply while increasing the likelihood that receivers will receive a signal at least once during a certain time period, called irregular signal period. First, a set of transmission offsets is selected, the transmission offsets defining a relative transmission time in a burst, such that if a burst would be transmitted using the selected transmission offsets, a receiver with any valid reception gap configuration would receive at least one signal in its whole duration. Then, during an irregular signal period, signals are transmitted in a sequence of one or more consecutive bursts using each of the transmission offsets in the selected set at least once, wherein the sequence of bursts may be preceded and/or followed by a period of no signal transmission.

Abstract: An isolated protein selected from the group consisting of (i) proteins comprising an amino acid sequence having at least 70% identity to the C-terminal domain of lung surfactant protein C precursor (CTproSP-C, “CTC”) from a mammal; and (ii) proteins comprising an amino acid sequence having at least 70% identity to the Brichos domain of CTproSP-C from a mammal, is disclosed for treatment of Alzheimer's disease in a mammal, including man.

Abstract: A method and system for transmitting data to user equipment (UE) is disclosed. In one embodiment, the system includes: a downlink transmitter configured to transmit a first data unit to the UE using a first transmission process assigned to the UE; an uplink receiver configured to receive a status signal indicating either a successful or unsuccessful reception of the first data unit by the UE; and a downlink scheduler, communicatively coupled to the downlink transmitter and uplink receiver, and configured to receive the status signal from the uplink receiver, wherein the downlink scheduler is further configured to schedule transmission of a second data unit to the UE and transmit a corresponding scheduling decision to the downlink transmitter prior to receiving the status signal, and wherein upon receiving the scheduling decision, the downlink transmitter transmits the second data unit to the UE using a second transmission process assigned to the UE.

Abstract: In a heterogeneous network deployment that includes a macro base station and one or more low power nodes, a discovery signal is transmitted to facilitate the identification of low power nodes. The discovery signal is transmitted on a selected subset of resource elements, previously unused, to maintain backward compatibility with legacy user equipment. The transmission sequence and/or the locations of resource elements used for transmitting the discovery signal can identify the low power node to a user equipment.

Abstract: An auxiliary cell identity (ACI) is proposed besides the conventional physical cell identity carried on the synchronization channels. The ACI is designed and configured to be transmitted in one or more primary regions and one or more secondary regions and transmitted by a base station/cell to a plurality of user equipment (UEs) located within coverage of the cell in one or more transmissions. Each of the UEs is configured to detects the transmitted ACI and identifies the cell based on the detected ACI.

Abstract: In a heterogeneous wireless network that includes a macro base station and one or more micro base stations, a wireless device to wirelessly transmit, in a first time slot at a first position in a first transmission subframe, data over a first physical communication channel. An ACK/NACK control message is received over a backhaul network connection a first time period after the first time slot. A response message is transmitted to the wireless device such that when the control message is received prior to the second time slot, then the response message uses data reception information from the control message and when the control message is not received prior to the second time slot, then the response message indicates that the data was successfully received.

Abstract: Provided is a synchronization cell used in a wireless communication system. Also provided is an SCI, synchronization cell indicator. A mobile network includes a processor that identifies one or more suitable synchronization cells for a user equipment (UE) and sends the SCI to the UE so that the UE can at least partially synchronize with a synchronization cell. The SCI advantageously includes a cell-id and other synchronization parameters and characteristics in various embodiments. The SCI may include a cell-directed UE action for the UE to carry out with a target cell. The UE carries out cell-directed UE actions with the target cell either after having obtained synchronization with the synchronization cell or to continue the synchronization process.

Abstract: In a heterogeneous network deployment that includes one or more macro base stations and one or more low power nodes, a technique can be provided to encode network operational information using phase differences in synchronization signals transmitted by a network node. The synchronization signals may be one of the first signals that a user equipment (UE) attempts to locate when attempting to join a wireless network. The phase-encoded network operational information indicates to the UE where to locate a geometry indicator transmission from a low power node that is a part of the network, but is not the node that transmits the synchronization signals. The geometry indicator transmission may include identity information for the transmitting node and may be transmitted at a pre-determined nominal transmit power.

Abstract: A cellular telecommunications system and method of scheduling a group of user equipments is provided. The system includes a macro cell with a macro base station and multiple associated low power nodes (LPN's). The macro base station and the LPN's share the same cell ID. The system and method provide for scheduling a group of UE's by grouping a plurality of the UE's together, assigning a group identifier to the group, notifying the group and encoding a control channel with the group identifier. A single control channel is delivered to each UE in the group of UE's. The UE's of the group of UE's may be processed by different LPN's. The transmitted control channel may be included in a DCI (downlink control information) and delivers uplink scheduling grants to the UE's. Based on the transmitted control channel, the UE's are scheduled for uplink transmission.

Abstract: A gyratory crusher outer crushing shell and a crushing shell assembly. The crushing shell includes a radially inward facing crushing surface and a radially outward facing mount surface provided with radially outward projecting contact regions to contact the topshell or an intermediate spacer ring. A ledge or groove providing an abutment face is positioned at or axially above the upper contact region to positionally support a sealing ring for positioning between the crushing shell and the topshell or intermediate spacer ring.

Abstract: A protein structure capable of selective interaction with an organic target is provided. The protein structure is a polymer comprising as a repeating structural unit a recombinant fusion protein that is capable of selective interaction with the organic target. The fusion protein is comprising the moieties B, REP and CT, and optionally NT. B is a non-spidroin moiety of more than 30 amino acid residues, which provides the capacity of selective interaction with the organic target. REP is a moiety of from 70 to 300 amino acid residues and is derived from the repetitive fragment of a spider silk protein. CT is a moiety of from 70 to 120 amino acid residues and is derived from the C-terminal fragment of a spider silk protein. NT is an optional moiety of from 100 to 160 amino acid residues and is derived from the N-terminal fragment of a spider silk protein. The fusion protein and protein structure thereof is useful as an affinity medium and a cell scaffold material.

Abstract: In a heterogeneous network deployment that includes a macro base station and one or more low power nodes, a geometry indicator signal is transmitted to facilitate the determination of geometry or location at a user equipment. The geometry indicator, in general, is transmitted on the same or different frequency as the data signal transmission and is transmitted over a range that is same or different from that of the data signal transmission. The geometry indicator signal may be transmitted by the macro base station, the low power nodes or both.

Abstract: A heterogeneous wireless communication network includes a macrocell base station that one or more low power nodes. The location of a wireless device is estimated based on feedback reports received from the wireless device in response to downlink transmissions of a reference signal. Based on the estimated location, a schedule for future transmissions of the reference signal to the wireless device are determined. The schedule specifies a frequency of transmission of the reference signals. The schedule specifies downlink transmission antenna configuration to be used for the reference signal transmissions.