Patents by Inventor Jan Kieleczawa

Jan Kieleczawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for promoting specific alignment of short oligonucleotides on nucleic acids
    Patent number: 5547843
    Abstract: Disclosed is a method for promoting specific alignment of short oligonucleotides on a nucleic acid polymer. The nucleic acid polymer is incubated in a solution containing a single-stranded DNA-binding protein and a plurality of oligonucleotides which are perfectly complementary to distinct but adjacent regions of a predetermined contiguous nucleotide sequence in the nucleic acid polymer. The plurality of oligonucleotides anneal to the nucleic acid polymer to form a contiguous region of double stranded nucleic acid. Specific application of the methods disclosed include priming DNA synthesis and template-directed ligation.
    Type: Grant
    Filed: October 18, 1994
    Date of Patent: August 20, 1996
    Assignee: Associated Universities, Inc.
    Inventors: F. William Studier, Jan Kieleczawa, John J. Dunn