Patents by Inventor JAN KRÖNKE

JAN KRÖNKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • X-RAY IMAGE PROCESSING SYSTEM, X-RAY IMAGING SYSTEM AND METHOD FOR PROCESSING AN X-RAY IMAGE
    Publication number: 20250072853
    Abstract: The invention relates to an X-ray image processing system (4) comprising an X-ray image input interface (8), a computing unit (9) and an X-ray image output interface (11). The X-ray image input interface (8) is configured to receive original X-ray images taken by an X-ray imaging system (1) comprising an X-ray source (2) and an X-ray detector (3). The computing unit (9) is connected to the X-ray image input interface (8) and is configured to obtain at least one original X-ray image from the X-ray image input interface (8), obtain information relating to the relative detector pose of the X-ray detector (3) relative to the X-ray source (2) and obtain a point of interest (P) in the original X-ray image, wherein the point of interest (P) is an anatomical structure or a part within an anatomical structure.
    Type: Application
    Filed: December 6, 2022
    Publication date: March 6, 2025
    Inventors: DANIEL BYSTROV, LENA CHRISTINA, SVEN KROENKE-HILLE, ANDRE GOOBEN, JAN MAREK MAY, JENS VON BERG, STEWART YOUNG, HEINER MATTHIAS BRUECK
  • Disease biomarkers and treatment methods related thereto
    Patent number: 11785925
    Abstract: The present invention features a knock-in mouse comprising a mutation in an endogenous CRBN locus and methods of use thereof.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: October 17, 2023
    Assignees: THE BROAD INSTITUTE, INC., THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Benjamin Levine Ebert, Jan Krönke, Steven A. Carr, Namrata D. Udeshi, Emma Fink
  • KNOCK-IN RODENT COMPRISING A MUTATION IN AN ENDOGENOUS CRBN LOCUS AND METHODS OF USE THEREOF
    Publication number: 20190274292
    Abstract: The present invention features a knock-in mouse comprising a mutation in an endogenous CRBN locus and methods of use thereof.
    Type: Application
    Filed: May 10, 2019
    Publication date: September 12, 2019
    Applicants: THE BROAD INSTITUTE, INC., THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: BENJAMIN LEVINE EBERT, JAN KRÖNKE, STEVEN A. CARR, NAMRATA D. UDESHI, EMMA FINK
  • IMiD screening methods IMiD-sensitive cells with mutant CRBN
    Patent number: 10334829
    Abstract: The present invention features a knock-in mouse comprising a mutation in an endogenous CRBN locus and methods of use thereof.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: July 2, 2019
    Assignees: The Broad Institute, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Benjamin Levine Ebert, Jan Krönke, Steven A. Carr, Namrata D. Udeshi, Emma Fink
  • KNOCK-IN RODENT COMPRISING A MUTATION IN AN ENDOGENOUS CRBN LOCUS AND METHODS OF USE THEREOF
    Publication number: 20180343839
    Abstract: The present invention features a knock-in mouse comprising a mutation in an endogenous CRBN locus and methods of use thereof.
    Type: Application
    Filed: April 17, 2018
    Publication date: December 6, 2018
    Applicants: THE BROAD INSTITUTE, INC., THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: BENJAMIN LEVINE EBERT, JAN KRÖNKE, STEVEN A. CARR, NAMRATA D. UDESHI, EMMA FINK
  • Knock-in rodent comprising a mutation in an endogenous CRBN locus and methods of use thereof
    Patent number: 9974289
    Abstract: The present invention features a knock-in mouse comprising a mutation in an endogenous CRBN locus and methods of use thereof.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: May 22, 2018
    Assignees: The Broad Institute, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Benjamin Levine Ebert, Jan Krönke, Steven A. Carr, Namrata D. Udeshi, Emma Fink
  • KNOCK-IN RODENT COMPRISING A MUTATION IN AN ENDOGENOUS CRBN LOCUS AND METHODS OF USE THEREOF
    Publication number: 20160338326
    Abstract: The present invention features a knock-in mouse comprising a mutation in an endogenous CRBN locus and methods of use thereof.
    Type: Application
    Filed: March 18, 2016
    Publication date: November 24, 2016
    Applicants: THE BROAD INSTITUTE, INC., THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: BENJAMIN LEVINE EBERT, JAN KRÖNKE, STEVEN A. CARR, NAMRATA D. UDESHI, EMMA FINK
  • COMPOSITIONS AND METHODS FOR SELECTING A TREATMENT FOR B-CELL NEOPLASIAS
    Publication number: 20160282354
    Abstract: The present invention features compositions and methods for identifying a subject having a B cell neoplasia or related condition responsive to treatment with lenalidomide and lenalidoinide-related compounds.
    Type: Application
    Filed: November 7, 2014
    Publication date: September 29, 2016
    Applicants: THE BROAD INSTITUTE, INC., THE BRIGHAM & WOMEN'S HOSPITAL, INC.
    Inventors: BENJAMIN LEVINE EBERT, STEVEN A. CARR, JAN KRÖNKE, NAMRATA D. UDESHI, EMMA FINK