Patents by Inventor Jan Lessem

Jan Lessem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating medical conditions
    Publication number: 20090005358
    Abstract: The invention features methods, compositions, and kits for the treatment of pain or pruritus in a patient. In one embodiment, the methods, compositions, and kits of the invention provide for a combination therapy including a tricyclic compound and a tetra-substituted pyrimidopyrimidine.
    Type: Application
    Filed: June 24, 2008
    Publication date: January 1, 2009
    Inventor: Jan Lessem
  • Methods and compositions for the treatment of diseases or conditions associated with increased C-reactive protein levels
    Publication number: 20080025965
    Abstract: The invention features methods and compositions for reducing the serum C-reactive protein (CRP) level in a patient in need thereof, and for treating diseases and conditions associated with an increased serum CRP level. The invention also features methods and compositions for treating a patient diagnosed with, or at risk of developing, periodontal disease by administering a tricyclic compound or an analog thereof and/or a tetra-substituted pyrimidopyrimidine or an analog thereof. The invention also features methods and compositions for reducing the serum CRP level in a patient in need thereof, and for treating diseases and conditions associated with an increased serum CRP level.
    Type: Application
    Filed: June 6, 2007
    Publication date: January 31, 2008
    Inventor: Jan Lessem
  • Methods and compositions for the treatment of diseases or conditions associated with increased C-reactive protein, interleukin-6, or interferon-gamma levels
    Publication number: 20080003213
    Abstract: The invention features methods and compositions for reducing the serum C-reactive protein (CRP), IL-6, and/or IFN-? levels in a patient in need thereof, and for treating diseases and conditions associated with an increased serum CRP, IL-6, and/or IFN-? levels. The invention also features methods and compositions for treating a patient diagnosed with, or at risk of developing, periodontal disease by administering a corticosteroid or an analog thereof and/or a tetra-substituted pyrimidopyrimidine or an adenosine analog upregulator.
    Type: Application
    Filed: May 21, 2007
    Publication date: January 3, 2008
    Inventor: Jan Lessem
  • Methods, compositions, and kits for the treatment of musculoskeletal disorders and symptoms associated therewith
    Publication number: 20070213308
    Abstract: The invention features methods, compositions, and kits for treating a musculoskeletal disorder, e.g., osteoarthritis, or pain, fatigue, tenderness, impairment in mobility, soft tissue swelling, or bony swelling associated therewith, by administering to a patient diagnosed with or at risk of developing such pain, fatigue, tenderness, impairment in mobility, soft tissue swelling, or bony swelling a tetra-substituted pyrimidopyrimidine, e.g., dipyridamole, or an adenosine activity upregulator, in combination with one or more additional agents. The invention further features methods, compositions, and kits for treating a patient diagnosed with or at risk of developing a musculoskeletal disorder by administering to the patient a tetra-substituted pyrimidopyrimidine or an adenosine activity upregulator in combination with one or more additional agents.
    Type: Application
    Filed: January 25, 2007
    Publication date: September 13, 2007
    Inventors: Jan Lessem, Yanzhen Zhang