Patents by Inventor Jan Ljunggren

Jan Ljunggren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070060740
    Abstract: The present invention is in the fields of biotechnology, protein purification and crystallization, x-ray diffraction analysis, three-dimensional computer molecular modelling and rational drug design. The invention is directed to the Liver X receptor and ligands for this receptor, and in particular to crystalline Liver X receptor beta (LXR?) and to methods of identifying ligands utilizing LXR?, as well as to compounds, compositions and methods for selecting, making, and using therapeutic or diagnostic agents having LXR? modulating or binding activity.
    Type: Application
    Filed: December 24, 2003
    Publication date: March 15, 2007
    Inventors: Mathias Farnegardh, Tornas Bonn, Sherry Sun, Jan Ljunggren, Harri Ahola, Mats Carlquist
  • Patent number: 6476196
    Abstract: The present invention is directed to crystals of ER&bgr; ligand binding domain complexed with (1) N-(n-butyl)-11-[3,17&bgr;-dihydroxyestra-1,3,5(10)-trien-7&agr;-yl]N-methylundecanamide; estradiol and a peptide comprising the amino acid sequence LXXLL; or 17-epiestriol and a peptide comprising the amino acid sequence LXXLL.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: November 5, 2002
    Assignee: Kara Bio AB
    Inventors: Jan Ljunggren, Ann-Gerd Thorsell, Owe Engstrom, Tomas Bonn, Mats Carlquist, Andrzeji Brzozowski, Ashley Pike, Roderick Hubbard
  • Patent number: 6228990
    Abstract: The application relates to a crystal comprising at least 150 amino acid residues of the estrogen receptor-&bgr; (ER&bgr;) ligand binding domain complexed with a ligand which is an antagonist or a partial agonist.
    Type: Grant
    Filed: February 12, 1999
    Date of Patent: May 8, 2001
    Assignee: Kara Bio AB
    Inventors: Jan Ljunggren, Ann-Gerd Thorsell, Owe Engstrom, Tomas Bonn, Mats Carlquist, Andrzej M. Brzozowski, Ashley C. W. Pike, Roderick E. Hubbard