Patents by Inventor Jan Maciejewski

Jan Maciejewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS TO CNS TISSUE
    Publication number: 20250223597
    Abstract: Disclosed herein are compounds comprising lipid PK/PD modulators for delivery of oligonucleotide-based agents, e.g., double-stranded RNAi agents, to certain cell types, such for example, CNS cells, in vivo. The PK/PD modulators disclosed herein, when conjugated to an oligonucleotide-based therapeutic or diagnostic agent, such as an RNAi agent, can enhance the delivery of the composition to the specified cells being targeted to facilitate the inhibition of gene expression in those cells.
    Type: Application
    Filed: December 13, 2024
    Publication date: July 10, 2025
    Inventors: Xiaokai Li, Tao Pei, Phillip Lazzara, Susan Phan, Teng Ai, Feng Liu, George Naclerio, III, Andrei V. Blokhin, Susan Ramos-Hunter, Jan Maciejewski
  • Auxiliary apparatus for manufacturing strips and sheets, coated on one side with a protective coating
    Patent number: 4461419
    Abstract: An apparatus which performs both the joining and the separating of juxtaposed strips to be coated including a stretcher leveller with two seam welders positioned between the entry and exit bridle rolls. Such an arrangement permits continuous stretch leveling of the juxtaposed strips during welding.
    Type: Grant
    Filed: June 23, 1981
    Date of Patent: July 24, 1984
    Assignee: Instytut Metalurgii Zelaza IM. Stanislawa Staszica
    Inventors: Boleslaw Mitka, Tadeusz Prajsnar, Karol Mniszek, Wilhelm Gorecki, Franciszek E. Kolodziejczyk, Jan Madry, Ryszard Kielpinski, Boguslaw Gorecki, Kazimierz Kucharski, Edmund Richta, Jan Maciejewski