Patents by Inventor Jan Mengler

Jan Mengler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW PLATINUM IV COMPLEXES WITH SUBSTANTIALLY INCREASED ANTITUMOR EFFICACY
    Publication number: 20220289781
    Abstract: Invention relates to new platinum (IV) complexes with substantially increased antitumor efficacy. A process for preparing said new platinum (IV) complexes is described. A pharmaceutical composition and a final dosage form for oral administration of the new platinum (IV) complexes is described. The use of the new platinum (IV) complex in a method to treat a tumor disease, preferably a heavy-to-treat cancer, most preferably pancreatic cancer, preferably by oral administration, is described.
    Type: Application
    Filed: September 5, 2019
    Publication date: September 15, 2022
    Inventors: Vladimír KYSILKA, Jan MENGLER, Milos MIKOSKA
  • Process for preparing trichloroammineplatinate salt and the products obtained therein
    Patent number: 8580212
    Abstract: The present invention relates to a process for preparing a trichloroammineplatinate salt by reacting a tetrachloroplatinate salt in aqueous solution in the presence of ammonium chloride and an alkali chloride with one or more carbonate salts selected from the group consisting of potassium, sodium and ammonium carbonate while keeping the pH value below 7 during the reaction; the product obtained therein and a use thereof.
    Type: Grant
    Filed: June 20, 2009
    Date of Patent: November 12, 2013
    Assignee: VUB Pharma A.S.
    Inventors: Vladimir Kysilka, Jan Mengler, Petr Kacer, Libor Cerveny, Karel Havlovic, Lucie Potucka
  • PROCESS FOR PREPARING TRICHLOROAMMINEPLATINATE SALT AND THE PRODUCTS OBTAINED THEREIN
    Publication number: 20120149907
    Abstract: The present invention relates to a process for preparing a trichloroammineplatinate salt by reacting a tetrachloroplatinate salt in aqueous solution in the presence of ammonium chloride and an alkali chloride with one or more carbonate salts selected from the group consisting of potassium, sodium and ammonium carbonate while keeping the pH value below 7 during the reaction; the product obtained therein and a use thereof.
    Type: Application
    Filed: June 20, 2009
    Publication date: June 14, 2012
    Applicant: VUB Pharma A.S.
    Inventors: Vladimir Kysilka, Jan Mengler, Petr Kacer, Libor Cerveny, Karel Havlovic, Lucie Potucka
  • Process for the preparation of an oxaliplatin
    Patent number: 7872150
    Abstract: The present invention relates to an improved process for the preparation of oxaliplatin, the obtained oxaliplatin preparation and its use in cancer therapy.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: January 18, 2011
    Assignee: Vuab Pharma A.S.
    Inventors: Vladimir Kysilka, Jan Mengler, Petr Kacer, Libor Cerveny
  • PROCESS FOR THE PREPARATION OF AN OXALIPLATIN
    Publication number: 20100174102
    Abstract: The present invention relates to an improved process for the preparation of oxaliplatin, the obtained oxaliplatin preparation and its use in cancer therapy.
    Type: Application
    Filed: June 8, 2006
    Publication date: July 8, 2010
    Inventors: Vladimir Kysilka, Jan Mengler, Petr Kacer, Libor Cerveny