Patents by Inventor Jan Mous

Jan Mous has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150216942
    Abstract: The present invention relates to insulin- and insulin analogue-carrying nanoparticles formulated together with or for use with free insulin or with an insulin analogue, such as a rapidly-acting insulin analogue. The compositions of the present invention find use in medicine, particularly in glycemic control, e.g. for controlling blood glucose levels in diabetic subjects. Nanoparticle compositions of the invention, formulated together with or for use with free insulin or with an insulin analogue, comprise a nanoparticle comprising a core comprising a metal and/or a semiconductor; and a corona comprising a plurality of ligands covalently linked to the core, wherein said plurality of ligands comprise at least one carbohydrate moiety; and at least one insulin peptide and/or insulin analogue peptide that is non-covalently bound to the corona.
    Type: Application
    Filed: January 29, 2015
    Publication date: August 6, 2015
    Inventors: Thomas Rademacher, Jan Mous
  • Publication number: 20150190476
    Abstract: A therapeutic or bioeffecting film delivery system which includes nanoparticles having actives bound to or associated with the nanoparticles and which when administered allow the active to perform a therapeutic or bioeffecting function.
    Type: Application
    Filed: February 9, 2015
    Publication date: July 9, 2015
    Inventors: Alexander M. Schobel, Garry L. Myers, Keith Joseph Kendall, Thomas Rademacher, Jan Mous, Justin N. W. Barry, Phillip Williams, Africa Garcia Barrientos
  • Patent number: 8974826
    Abstract: A therapeutic or bioeffecting film delivery system which includes nanoparticles having actives bound to or associated with the nanoparticles and which when administered allow the active to perform a therapeutic or bioeffecting function.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: March 10, 2015
    Assignees: Monosol RX, LLC, Midatech Limited
    Inventors: Alexander M. Schobel, Garry L. Myers, Keith Joseph Kendall, Thomas Rademacher, Jan Mous, Justin N. W. Barry, Phillip Williams, Africa Garcia Barrientos
  • Publication number: 20120009260
    Abstract: A therapeutic or bioeffecting film delivery system which includes nanoparticles having actives bound to or associated with the nanoparticles and which when administered allow the active to perform a therapeutic or bioeffecting function.
    Type: Application
    Filed: June 10, 2011
    Publication date: January 12, 2012
    Inventors: Alexander M. Schobel, Garry L. Myers, Keith Joseph Kendall, Thomas Rademacher, Jan Mous, Justin N. W. Barry, Phillip Williams, Africa Garcia Barrientos
  • Patent number: 7358049
    Abstract: The present invention relates to methods of identifying genes involved in memory formation. This is accomplished by performing a gene chip identification of those genes expressed during transcription-dependent memory formation but not during transcription-independent memory formation. A statistical analysis of the gene chip identification output yields a set of genes that are involved in transcription-dependent memory formation.
    Type: Grant
    Filed: August 8, 2005
    Date of Patent: April 15, 2008
    Assignees: Cold Spring Harbor Laboratory, Emory University, Hoffmann-La Roche Inc.
    Inventors: Timothy P. Tully, Joshua I. Dubnau, Michael Davis, Jan Mous, Ulrich Certa
  • Publication number: 20060068422
    Abstract: The present invention relates to methods of identifying genes involved in memory formation. This is accomplished by performing a gene chip identification of those genes expressed during transcription-dependent memory formation but not during transcription-independent memory formation. A statistical analysis of the gene chip identification output yields a set of genes that are involved in transcription-dependent memory formation.
    Type: Application
    Filed: August 8, 2005
    Publication date: March 30, 2006
    Inventors: Timothy Tully, Joshua Dubnau, Michael Davis, Jan Mous, Ulrich Certa
  • Patent number: 7005256
    Abstract: The present invention relates to methods of identifying genes involved in memory formation. This is accomplished by performing a gene chip identification of those genes expressed during transcription-dependent memory formation but not during transcription-independent memory formation. A statistical analysis of the gene chip identification output yields a set of genes that are involved in transcription-dependent memory formation.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: February 28, 2006
    Assignees: Cold Spring Harbor Laboratory, Emory University, Hoffmann-La Roche Inc.
    Inventors: Timothy P. Tully, Joshua I. Dubnau, Michael Davis, Jan Mous, Ulrich Certa
  • Patent number: 5874533
    Abstract: Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A method for the detection of HIV antibodies or HIV viruses in human sera or in other biological fluids is also provided.
    Type: Grant
    Filed: March 15, 1994
    Date of Patent: February 23, 1999
    Assignee: Roche Diagnostic Systems, Inc.
    Inventors: Wilhelm Bannwarth, Patrick Caspers, Stuart Le Grice, Jan Mous
  • Patent number: 5780038
    Abstract: Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A method for the detection of HIV antibodies or HIV viruses in human sera or in other biological fluids is also provided.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: July 14, 1998
    Assignee: Roche Diagnostic Systems, Inc.
    Inventors: Wilhelm Bannwarth, Patrick Caspers, Stuart Le Grice, Jan Mous
  • Patent number: 5702918
    Abstract: Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A method for the detection of HIV antibodies or HIV viruses in human sera or in other biological fluids is also provided.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: December 30, 1997
    Assignee: Roche Diagnostic Systems, Inc.
    Inventors: Wilhelm Bannwarth, Patrick Caspers, Stuart Le Grice, Jan Mous