Patents by Inventor Jan Robert Krähling

Jan Robert Krähling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLIC CHEMERIN-9 DERIVATIVES
    Publication number: 20230303647
    Abstract: The present invention relates to cyclic chemerin-9 derivatives of general formula (I) as described and defined herein, methods of preparing said peptides, and the use of said compounds for the treatment or prophylaxis of diseases, in particular cancer, diabetes, obesity and inflammatory disorders.
    Type: Application
    Filed: August 10, 2021
    Publication date: September 28, 2023
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jan Robert KRÄHLING, Bernd RIEDL, Annette BECK-SICKINGER, Tobias FISCHER, Anne CZERNIAK, Sylvia ELS-HEINDL
  • METHODS TO DETERMINE WHETHER A SUBJECT IS SUITABLE OF BEING TREATED WITH AN AGONIST OF SOLUBLE GYANYLYL CYCLASE (SGC)
    Publication number: 20220128561
    Abstract: The present invention provides a method for determining whether a human or animal subject suffers from oxidative stress, is suitable of being treated with an antioxidant and/or free radical scavenger, and/or is suitable of being treated with an agonist of soluble Guanylyl Cyclase (sGC), in particular with an activator of sGC, said method comprising the steps of providing a tissue or liquid sample from said subject, and determining whether or not said sample is characterized by the presence, upregulation or overexpression of sGC comprising a heme free ?1 subunit.
    Type: Application
    Filed: January 16, 2020
    Publication date: April 28, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Rene Hoet, Peter Sandner, Jan Robert Krähling, Agnes Benardeau, Ana Lúcia Freitas de Mesquita Barbas, Ligia Nobre, Hugo Soares, Gabriela Silva