Abstract: An intravascular imaging device may include a shaft with proximal and distal end regions, and an imaging assembly movably disposed within the shaft. The imaging assembly may comprise a drive cable, a housing coupled to the drive cable's distal end, a transducer within the housing, and a coaxial cable extending through the drive cable and electrically coupled to the transducer. The coaxial cable may be electrically coupled to a connection point on an upper surface of the transducer and electrically coupled to the housing. The device may include different configurations of the coaxial cable, such as a first member electrically coupled to the connection point and a second member electrically coupled to the housing. The housing may have various regions, including a cavity for receiving the transducer.

Abstract: An intravascular imaging device may include a shaft with proximal and distal end regions, and an imaging assembly movably disposed within the shaft. The imaging assembly may comprise a drive cable, a housing coupled to the drive cable's distal end, a transducer within the housing, and a coaxial cable extending through the drive cable and electrically coupled to the transducer. The device may feature electrical connections between the coaxial cable components and the transducer or housing, and may include specific housing configurations to accommodate the transducer and facilitate electrical connections.

Abstract: Intravascular imaging devices and backing layers are disclosed. An example intravascular imaging device may include an elongate shaft having a lumen formed therein. An imaging core may be disposed within the lumen. An imaging transducer may be coupled to a distal end region of the imaging core. The imaging transducer may include an active layer and a backing layer. The backing layer may include an electrically conductive adhesive and tungsten particles dispersed therein. The backing layer may have an attenuation of 70 dB or greater.

Abstract: An intravascular imaging device may include a shaft with proximal and distal end regions, and an imaging assembly movably disposed within the shaft. The imaging assembly may comprise a drive cable, a housing coupled to the drive cable's distal end, a transducer within the housing, and a coaxial cable extending through the drive cable and electrically coupled to the transducer. The housing may include a proximal end region with a first inner diameter, an intermediate region with a cavity for receiving the transducer, and a distal end region with a substantially solid cross-section. The intermediate region may have a generally planar inner surface extending at a non-parallel angle relative to the imaging assembly's longitudinal axis.

Abstract: Imaging medical device systems and methods for making and using imaging medical device systems are disclosed. An example imaging medical device system may include an elongate shaft having a distal end region. An imaging assembly may be disposed within the elongate shaft. The imaging assembly may include a drive cable, a housing coupled to the drive cable, and a transducer coupled to the housing. A bubble-reducing member may be disposed adjacent to the drive cable.

Abstract: The present disclosure relates generally to controlled extension medical stents, and more particularly to controlled extension devices positioned in the body to stent the ureter and facilitate drainage from the kidney to the bladder.

Abstract: The present disclosure relates generally to controlled extension medical stents, and more particularly to controlled extension devices positioned in the body to stent the ureter and facilitate drainage from the kidney to the bladder.

Abstract: The present disclosure relates generally to controlled extension medical stents, and more particularly to controlled extension devices positioned in the body to stent the ureter and facilitate drainage from the kidney to the bladder.

Abstract: The present disclosure relates generally to controlled extension medical stents, and more particularly to controlled extension devices positioned in the body to stent the ureter and facilitate drainage from the kidney to the bladder.

Abstract: Imaging medical device systems and methods for making and using imaging medical device systems are disclosed. An example imaging medical device system may include an elongate shaft having a distal end region. An imaging assembly may be disposed within the elongate shaft. The imaging assembly may include a drive cable, a housing coupled to the drive cable, and a transducer coupled to the housing. A bubble-reducing member may be disposed adjacent to the drive cable.

Abstract: In one aspect, the present disclosure pertains to lubricous coating compositions that comprise (a) a higher molecular weight polyvinylpyrrolidone, (b) a lower molecular weight polyvinylpyrrolidone, (c) a copolymer of sodium acrylate and acrylamide or a copolymer of acrylic acid and acrylamide, and (d) a polyfunctional unsaturated crosslinking agent. In some embodiments, such lubricous coating compositions are present in crosslinked form on the surface of a medical article. In some embodiments, the lubricous coating compositions further comprise a solvent, in which case such compositions may be, for example, applied to a substrate in the form of a layer and subsequently crosslinked, thereby forming a lubricious coating on the substrate.

Abstract: The present disclosure relates generally to controlled extension medical stents, and more particularly to controlled extension devices positioned in the body to stent the ureter and facilitate drainage from the kidney to the bladder.

Abstract: A biocompatible polyisobutylene urethane, urea, and urethane/urea copolymer including hard segments, soft segments and that is free of urethane, urea or urethane/urea solvents. The hard include diisocyanate residue. The soft segments include at least one polyisobutylene diol or diamine and optionally a polyether diol.

Abstract: In one aspect, the present disclosure pertains to lubricous coating compositions that comprise (a) a higher molecular weight polyvinylpyrrolidone, (b) a lower molecular weight polyvinylpyrrolidone, and (c) a polyfunctional unsaturated crosslinking agent. In some embodiments, such lubricous coating compositions are present in crosslinked form on the surface of a medical article. In some embodiments, the lubricous coating compositions further comprise a solvent, in which case such compositions may be, for example, applied to a substrate in the form of a layer and subsequently crosslinked, thereby forming a lubricious coating on the substrate. In another aspect, the present disclosure is directed to methods for forming various medical articles.

Abstract: A medical electrical lead may include an insulative lead body, a conductor disposed within the insulative lead body, an electrode disposed on the insulative lead body and in electrical contact with the conductor and a fibrous matrix disposed at least partially over the electrode. The fibrous matrix may be formed from a polyisobutylene urethane, urea or urethane/urea copolymer.

Abstract: A stent delivery system which includes a stent delivery catheter, the stent delivery catheter having a stent mounting region, the stent mounting region having an inflatable portion. A stent is disposed about the stent mounting region, the stent having an unexpanded position and an expanded position. At least one stent retaining sleeve is also included having first and second ends, the first end being attached to the stent delivery catheter, the at least one stent retaining sleeve disposed about at least a portion of the stent in the unexpanded position, the stent retaining sleeve being constructed and arranged to retract toward the attached first end when the stent is expanded.

Abstract: According to an aspect of the present invention, a medical device is provided which comprises a metallic substrate and polymeric region disposed over and in contact with the metallic substrate. The polymeric region comprises (a) a block copolymer that comprises (i) a hard polymer block that comprises a high Tg monomer and (ii) a soft polymer block that comprises a low Tg monomer, (b) an adhesion promoting copolymer that comprises (i) a first monomer that covalently or non-covalently bonds with the metallic substrate and (ii) a second monomer that is compatible with the low Tg monomer and/or the high Tg monomer and (c) a therapeutic agent. The polymeric region may further comprise an optional polymer that is used to tailor the release rate of the therapeutic agent.

Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain one or more polymeric regions. These polymeric regions, in turn, contain one or more polymers, at least one of which is a copolymer that includes a styrene monomer and an isobutylene monomer. Moreover, the styrene monomer content of the copolymer typically ranges from 25 to 50 mol %.

Abstract: According to an aspect of the present invention, a medical device is provided which comprises a metallic substrate and polymeric region disposed over and in contact with the metallic substrate. The polymeric region comprises (a) a block copolymer that comprises (i) a hard polymer block that comprises a high Tg monomer and (ii) a soft polymer block that comprises a low Tg monomer, (b) an adhesion promoting copolymer that comprises (i) a first monomer that covalently or non-covalently bonds with the metallic substrate and (ii) a second monomer that is compatible with the low Tg monomer and/or the high Tg monomer and (c) a therapeutic agent. The polymeric region may further comprise an optional polymer that is used to tailor the release rate of the therapeutic agent.

Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain one or more polymeric regions. These polymeric regions, in turn, contain one or more polymers, at least one of which is a copolymer that includes a styrene monomer and an isobutylene monomer. Moreover, the styrene monomer content of the copolymer typically ranges from 25 to 50 mol %.