Patents by Inventor Jan T. Poolman

Jan T. Poolman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccine Protection Assay
    Publication number: 20080064057
    Abstract: The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular N. meningitidis. The SBA assay is the most important method for measuring functional activity of serum antibodies against meningococcus. In order to determine whether a subject or a population is seropositive against invasive meningococcus the SBA test should ideally be both sensitive and specific. The inventors have found the standard N. meningitidis serotype A and W SBAs can be significantly improved in this regard.
    Type: Application
    Filed: August 31, 2006
    Publication date: March 13, 2008
    Inventors: Isabel De Vleeschauwer, Nathalie Durant, Jan T. Poolman, Vincent Weynants
  • Recombinant microorganism expressing meningococcal class 1 outer membrane protein
    Patent number: 7238345
    Abstract: Outer-membrane vesicles, Class 1 outer membrane proteins of Neisseria meningitidis, fragments or oligopeptides containing epitopes of the Class I OMP can be used to immunize against meningococcal disease.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 3, 2007
    Assignee: Wyeth Holdings Corporation
    Inventors: Robert C. Seid, Jr., Peter R. Paradiso, Jan T. Poolman, Peter Hoogerhout, Emmanuel J. H. J. Wiertz, Peter van der Ley, John Edward Heckels, Ian Nicholas Clarke
  • Meningococcal class 1 outer-membrane protein vaccine
    Patent number: 7118757
    Abstract: Outer-membrane vesicles, Class 1 outer membrane proteins of Neisseria meningitidis, fragments or oligopeptides containing epitopes of the Class I OMP can be used to immunize against meningococcal disease.
    Type: Grant
    Filed: February 15, 1994
    Date of Patent: October 10, 2006
    Assignees: Wyeth Holdings Corporation, De Staat der Nederlanden Vertegenwoordigd Door de Minister Van Welzijn, Volksgezondheid en Cultuur
    Inventors: Robert C. Seid, Jr., Peter R. Paradiso, Jan T. Poolman, Peter Hoogerhout, Emmanuel J. H. J. Wiertz, Peter van der Ley, John Edward Heckels, Ian Nicholas Clarke
  • Oligosaccharides, immunogens and vaccines, and methods for preparing such oligosaccharides, immunogens and vaccines
    Patent number: 5034519
    Abstract: The invention relates to new oligosaccharides comprising the structure (D-ribose-D-ribitol-phosphate).sub.m, (D-ribitol-phosphate-D-ribose).sub.m or (phosphate-D-ribose-D-ribitol).sub.m, m being 2,3,4 . . . 19 or 20, to immunogens containing such oligosaccharide, to vaccines containing such immunogens and to methods for preparing such oligosaccharides, immunogens and vaccines. The vaccine is very suitable for treating infections caused by Haemophilus influenzae type b.
    Type: Grant
    Filed: December 29, 1987
    Date of Patent: July 23, 1991
    Assignee: De Staat Der Nederlanden
    Inventors: Eduard C. Beuvery, Adolf Evenberg, Jan T. Poolman, Jacobus H. van Boom, Peter Hoogerhout, Constant A. A. van Boeckel